A Randomized, Placebo-controlled Trial of Preemptive Antifungal Therapy for the Prevention of Invasive Candidiasis Following Gastrointestinal Surgery for Intra-abdominal Infections

W. Knitsch,J. Vincent,S. Utzolino,B. François,T. Dinya,G. Dimopoulos,I. Özgünes,J. Valía,P. Eggimann,C. León,P. Montravers,Stephen Phillips,Lorraine Tweddle,A. Karas,Malcolm Brown,O. Cornely

Published 2015 in Clinical Infectious Diseases

ABSTRACT

Patients undergoing emergency gastrointestinal surgery for intra-abdominal infection are at high risk for invasive candidiasis. This exploratory clinical trial could not provide evidence that a preemptive antifungal treatment strategy was effective in this patient group.

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