Dysregulation of the Norepinephrine Transporter Sustains Cortical Hypodopaminergia and Schizophrenia-Like Behaviors in Neuronal Rictor Null Mice

M. Siuta,S. Robertson,Heidi E. Kocalis,C. Saunders,P. Gresch,V. Khatri,C. Shiota,J. P. Kennedy,C. Lindsley,L. Daws,D. Polley,J. Veenstra-VanderWeele,G. Stanwood,M. Magnuson,K. Niswender,A. Galli,E. Nestler

Published 2010 in PLoS Biology

ABSTRACT

A novel animal model highlights the link between Akt dysfunction, reduced cortical dopamine function, norepinephrine transporters, and schizophrenia-like behaviors.

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