The requirement for the TCR to interact with coagonists, endogenous MHC–peptide complexes which do not themselves activate the T cell, decreases as the strength of the CD8–class I interaction increases.
Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide–MHC
John A. H. Hoerter,J. Brzostek,M. Artyomov,S. Abel,J. Casas,Vasily Rybakin,J. Ampudia,C. Lotz,J. Connolly,A. Chakraborty,K. Gould,N. Gascoigne
Published 2013 in Journal of Experimental Medicine
ABSTRACT
PUBLICATION RECORD
- Publication year
2013
- Venue
Journal of Experimental Medicine
- Publication date
2013-08-26
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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