eview daptation and learning of molecular networks as a description of ancer development at the systems-level : Potential use in nti-cancer therapies

ávid M. Gyurkóa,D. Veresa,Dezső Módosa,Katalin Lentib,amás Korcsmárosc,Péter Csermelya

Published 2013 in Unknown venue

ABSTRACT

No abstract is available for this paper.

PUBLICATION RECORD

Publication year
2013
Venue
Unknown venue
Publication date
Unknown publication date
Fields of study
Not labeled
Identifiers
No identifiers available.
External record
Open on Semantic Scholar
Source metadata
Semantic Scholar

CITATION MAP

EXTRACTION MAP

CLAIMS

No claims are published for this paper.

CONCEPTS

No concepts are published for this paper.

REFERENCES

Therapeutic Implications of Targeting Energy Metabolism in Breast Cancer
2013cited by this paper
Network, nodes and nexus: systems approach to multitarget therapeutics.
2013cited by this paper
Human diseases through the lens of network biology.
2013cited by this paper
Master transcription factors and mediator establish super-enhancers at key cell identity genes.
2013cited by this paper
Adaptation and learning of molecular networks as a description of cancer development at the systems-level: potential use in anti-cancer therapies.
2013cited by this paper
A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery.
2013cited by this paper
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
2013cited by this paper
Selective inhibition of tumor oncogenes by disruption of super-enhancers.
2013cited by this paper
MDM2, MDMX and p53 in oncogenesis and cancer therapy
2013cited by this paper
Beyond ‘furballs’ and ‘dumpling soups’ – towards a molecular architecture of signaling complexes and networks
2012cited by this paper
Navigating cancer network attractors for tumor-specific therapy
2012cited by this paper
Understanding cancer stem cell heterogeneity and plasticity
2012cited by this paper
Rigidity and flexibility of biological networks
2012cited by this paper
Crosstalk between transcription factors and microRNAs in human protein interaction network
2012cited by this paper
High-order chromatin architecture shapes the landscape of chromosomal alterations in cancer
2012cited by this paper
The Oncogenic Role of miR-155 in Breast Cancer
2012cited by this paper
TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers
2012cited by this paper
Structure and dynamics of molecular networks: A novel paradigm of drug discovery. A comprehensive review
2012cited by this paper
Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells
2012cited by this paper
Inter-cellular signaling network reveals a mechanistic transition in tumor microenvironment.
2012cited by this paper
Regulated noise in the epigenetic landscape of development and disease.
2012cited by this paper
Molecular signaling network complexity is correlated with cancer patient survivability
2012cited by this paper
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.
2012cited by this paper
Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.
2012cited by this paper
Rapid perturbation of free-energy landscapes: from in vitro to in vivo.
2012cited by this paper
Oncogene-mediated alterations in chromatin conformation
2012cited by this paper
Dynamics of DNA Damage Induced Pathways to Cancer
2012cited by this paper
Intra-tumour heterogeneity: a looking glass for cancer?
2012cited by this paper
Endosomal crosstalk: meeting points for signaling pathways
2012cited by this paper
microRNA Dysregulation in Prostate Cancer: Network Analysis Reveals Preferential Regulation of Highly Connected Nodes
2012cited by this paper
System level mechanisms of adaptation, learning, memory formation and evolvability: the role of chaperone and other networks.
2012cited by this paper
Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks
2012cited by this paper
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
2012cited by this paper
Differential network entropy reveals cancer system hallmarks
2012cited by this paper
Dynamics and control of state-dependent networks for probing genomic organization
2011cited by this paper
Mapping the disease protein interactome: toward a molecular medicine GPS to accelerate drug and biomarker discovery.
2011cited by this paper
A systems pharmacology analysis of major chemotherapy combination regimens used in gastric cancer treatment: predicting potential new protein targets and drugs.
2011cited by this paper
Temporal Networks
2011cited by this paper
Heat Shock Partially Dissociates the Overlapping Modules of the Yeast Protein-Protein Interaction Network: A Systems Level Model of Adaptation
2011cited by this paper
Systems biology and the future of medicine
2011cited by this paper
Do cancer proteins really interact strongly in the human protein-protein interaction network?
2011cited by this paper
Allo-network drugs: harnessing allostery in cellular networks.
2011cited by this paper
Heterogeneity maintenance in glioblastoma: a social network.
2011cited by this paper
Building Protein-Protein Interaction Networks with Proteomics and Informatics Tools*
2011cited by this paper
The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein*
2011cited by this paper
Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect
2011cited by this paper
Serine Biosynthesis with One Carbon Catabolism and the Glycine Cleavage System Represents a Novel Pathway for ATP Generation
2011cited by this paper
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation.
2011cited by this paper
An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer
2010cited by this paper
Reprogramming of miRNA networks in cancer and leukemia.
2010cited by this paper
Increased entropy of signal transduction in the cancer metastasis phenotype
2010cited by this paper
A Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Initially Mimicking Cutaneous Lupus Erythematosus
2010cited by this paper
Signal transduction networks in cancer: quantitative parameters influence network topology.
2010cited by this paper
Modeling Core Metabolism in Cancer Cells: Surveying the Topology Underlying the Warburg Effect
2010cited by this paper
Clonal evolution in cancer
2010cited by this paper
mTOR: from growth signal integration to cancer, diabetes and ageing
2010cited by this paper
Structure of Protein Interaction Networks and Their Implications on Drug Design
2009cited by this paper
Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective.
2009cited by this paper
The emergence of lineage-specific chromosomal topologies from coordinate gene regulation
2009cited by this paper
Defining network topologies that can achieve biochemical adaptation
2009cited by this paper
The basics of epithelial-mesenchymal transition.
2009cited by this paper
Dynamic modularity in protein interaction networks predicts breast cancer outcome
2009cited by this paper
Human Cancer Protein-Protein Interaction Network: A Structural Perspective
2009cited by this paper
Unfoldomics of human diseases: linking protein intrinsic disorder with diseases
2009cited by this paper
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
2008cited by this paper
Human metabolic network reconstruction and its impact on drug discovery and development.
2008cited by this paper
Protein co-evolution, co-adaptation and interactions
2008cited by this paper
Creative elements: network-based predictions of active centres in proteins and cellular and social networks.
2008cited by this paper
Regulatory network motifs and hotspots of cancer genes in a mammalian cellular signalling network.
2007cited by this paper
let-7 regulates self renewal and tumorigenicity of breast cancer cells.
2007cited by this paper
The Importance of Bottlenecks in Protein Networks: Correlation with Gene Essentiality and Expression Dynamics
2007cited by this paper
Human protein-protein interaction networks and the value for drug discovery.
2007cited by this paper
An integrated view of protein evolution
2006cited by this paper
Cancer: a Systems Biology disease.
2006cited by this paper
MicroRNA signatures in human cancers
2006cited by this paper
Evolution of cooperation among tumor cells
2006cited by this paper
Global topological features of cancer proteins in the human interactome
2006cited by this paper
Bioinformatics for Cancer Management in the Post-Genome Era
2006cited by this paper
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
2006cited by this paper
Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence.
2005cited by this paper
Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues
2005cited by this paper
Modularity and evolutionary constraint on proteins
2005cited by this paper
Cancer as a robust system: implications for anticancer therapy
2004influential reference
The efficiency of multi-target drugs: the network approach might help drug design.
2004cited by this paper
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004cited by this paper
Protein complexes and functional modules in molecular networks
2003cited by this paper
Network motifs: simple building blocks of complex networks.
2002cited by this paper
Intrinsic disorder in cell-signaling and cancer-associated proteins.
2002cited by this paper
Epithelial–mesenchymal transitions in tumour progression
2002cited by this paper
Analysis of a "phase transition" from tumor growth to latency.
2000cited by this paper
Surfing the p53 network
2000cited by this paper
Emergence of Scaling in Random Networks
1999cited by this paper
Cancer progression: The ultimate challenge
1989cited by this paper
Differentiation of malignant to benign cells.
1971cited by this paper
Seminars in Cancer Biology
year unknowncited by this paper

CITED BY

No citing papers are available for this paper.