Myocardial Na+/H+ exchanger-1 (NHE1) content is decreased by exercise training

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of physiology and biochemistry

• Publication date

  2012-10-05

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s13105-012-0214-7PMID 23055051
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• NHE-1 participates in isoproterenol-induced downregulation of SERCA2a and development of cardiac remodeling in rat hearts.

  2011cited by this paper
• Effect of N-2-mercaptopropionyl glycine on exercise-induced cardiac adaptations.

  2011cited by this paper
• The effect of different exercise‐testing protocols on atrial natriuretic peptide

  2011cited by this paper
• A novel chimeric natriuretic peptide reduces cardiomyocyte hypertrophy through the NHE-1-calcineurin pathway.

  2010cited by this paper
• Elevated Cytosolic Na+ Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes

  2010cited by this paper
• Endurance Training in the Spontaneously Hypertensive Rat: Conversion of Pathological into Physiological Cardiac Hypertrophy

  2009cited by this paper
• Cardiac anti‐remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice

  2009cited by this paper
• NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition.

  2008cited by this paper
• Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study.

  2008cited by this paper
• PROMOTING PHYSIOLOGICAL HYPERTROPHY IN THE FAILING HEART

  2008cited by this paper
• Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans.

  2008cited by this paper
• Enhanced Na+/H+ Exchange During Ischemia and Reperfusion Impairs Mitochondrial Bioenergetics and Myocardial Function

  2008cited by this paper
• Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury.

  2008cited by this paper
• Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise.

  2007cited by this paper
• Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium.

  2007cited by this paper
• Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction.

  2007cited by this paper
• Sodium-hydrogen exchanger, cardiac overload, and myocardial hypertrophy.

  2007cited by this paper
• Antihypertrophic Effect of Na+/H+ Exchanger Isoform 1 Inhibition Is Mediated by Reduced Mitogen-Activated Protein Kinase Activation Secondary to Improved Mitochondrial Integrity and Decreased Generation of Mitochondrial-Derived Reactive Oxygen Species

  2006cited by this paper
• Activation pattern of MAPK signaling in the hearts of trained and untrained rats following a single bout of exercise.

  2006cited by this paper
• NHE-1 inhibition improves cardiac mitochondrial function through regulation of mitochondrial biogenesis during postinfarction remodeling.

  2006cited by this paper
• Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.

  2006cited by this paper
• Reactive oxygen species-mediated regulation of the Na+–H+ exchanger 1 gene expression connects intracellular redox status with cells' sensitivity to death triggers

  2006cited by this paper
• Age‐associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging

  2005cited by this paper
• Effect of high-intensity intermittent training on lactate and H+ release from human skeletal muscle.

  2004cited by this paper
• The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.

  2004cited by this paper
• Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy

  2004cited by this paper
• The Insulin-like Growth Factor 1 Receptor Induces Physiological Heart Growth via the Phosphoinositide 3-Kinase(p110α) Pathway*

  2004cited by this paper
• Inhibition and reversal of myocardial infarction-induced hypertrophy and heart failure by NHE-1 inhibition.

  2004cited by this paper
• INFLUENCE OF AGE AND RUN TRAINING ON CARDIAC Na + -Ca 2+ EXCHANGE

  2003cited by this paper
• Regression of Hypertensive Myocardial Fibrosis by Na+/H+ Exchange Inhibition

  2003cited by this paper
• Influence of age and run training on cardiac Na+/Ca2+ exchange.

  2003cited by this paper
• Regression of Isoproterenol‐Induced Cardiac Hypertrophy by Na+/H+ Exchanger Inhibition

  2003cited by this paper
• Stimulation of the Plasma Membrane Na+/H+ Exchanger NHE1 by Sustained Intracellular Acidosis

  2003cited by this paper
• Mice With a Null Mutation in the NHE1 Na+-H+ Exchanger Are Resistant to Cardiac Ischemia-Reperfusion Injury

  2003cited by this paper
• Effects of body temperature during exercise training on myocardial adaptations.

  2001cited by this paper
• Increased contractility and calcium sensitivity in cardiac myocytes isolated from endurance trained rats.

  2001cited by this paper
• Expression of the Na(+)/H(+) exchanger isoform NHE1 in rat skeletal muscle and effect of training.

  2000cited by this paper
• Acute exercise can improve cardioprotection without increasing heat shock protein content.

  1999cited by this paper
• Acute exercise can improve cardioprotection without increasing heat shock protein content.

  1999cited by this paper
• Impact of different sports and training on cardiac structure and function.

  1997cited by this paper
• Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research.

  1997cited by this paper
• Bioenergetics in the aging Fischer 344 rat: effects of exercise and food restriction.

  1987cited by this paper
• Substrate dependence of metabolic state and coronary flow in perfused rat heart.

  1985cited by this paper
• The Tools of Biochemistry

  1977cited by this paper

• Editorial Special Issue: 2020 consortium for trans-pyrenean investigations on obesity and diabetes

  2022cites this paper
• Targeting NAD+: is it a common strategy to delay heart aging?

  2022cites this paper
• Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy

  2021cites this paper
• Exercise Attenuates Intermittent Hypoxia-Induced Cardiac Fibrosis Associated with Sodium-Hydrogen Exchanger-1 in Rats

  2016cites this paper
• Role of Sodium-Hydrogen Exchanger-1 (NHE-1) in the Effect of Exercise on Intermittent Hypoxia-Induced Left Ventricular Dysfunction.

  2015influential citation
• Physiological cardiac hypertrophy: critical role of AKT in the prevention of NHE-1 hyperactivity.

  2014cites this paper
• Exercise alters the regulation of myocardial Na(+)/H(+) exchanger-1 activity.

  2013cites this paper