METTL23, a transcriptional partner of GABPA, is essential for human cognition.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Human Molecular Genetics

• Publication date

  2014-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/hmg/ddu054PMID 24501276PMCID PMC4049305
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Downregulation of the Expression of Mitochondrial Electron Transport Complex Genes in Autism Brains

  2013cited by this paper
• A Newly Uncovered Group of Distantly Related Lysine Methyltransferases Preferentially Interact with Molecular Chaperones to Regulate Their Activity

  2013cited by this paper
• Haploinsufficiency of SOX5, a member of the SOX (SRY-related HMG-box) family of transcription factors is a cause of intellectual disability.

  2013cited by this paper
• Parent–child exome sequencing identifiesa de novo truncating mutation in TCF4 in non‐syndromic intellectual disability

  2013cited by this paper
• Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain

  2012cited by this paper
• Lysine methylation of VCP by a member of a novel human protein methyltransferase family

  2012cited by this paper
• Haploinsufficiency of ARID1B, a member of the SWI/SNF-a chromatin-remodeling complex, is a frequent cause of intellectual disability.

  2012cited by this paper
• Sequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.

  2012cited by this paper
• Prevalence of intellectual disability: a meta-analysis of population-based studies.

  2011cited by this paper
• Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

  2010cited by this paper
• PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.

  2010cited by this paper
• ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

  2010cited by this paper
• Haploinsufficiency of HDAC4 causes brachydactyly mental retardation syndrome, with brachydactyly type E, developmental delays, and behavioral problems.

  2010cited by this paper
• Genetics of early onset cognitive impairment.

  2010cited by this paper
• The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans

  2009cited by this paper
• PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an N-dimethyl lysine demethylase

  2009cited by this paper
• DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

  2008cited by this paper
• PLINK: a tool set for whole-genome association and population-based linkage analyses.

  2007influential reference
• X-linked mental retardation: many genes for a complex disorder.

  2006cited by this paper
• ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation.

  2006cited by this paper
• Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation.

  2005cited by this paper
• The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation

  2005cited by this paper
• Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome

  2005cited by this paper
• Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

  2005cited by this paper
• Tissue-specific overexpression of the HSA21 gene GABPα: implications for DS

  2004cited by this paper
• Zinc finger 81 (ZNF81) mutations associated with X-linked mental retardation

  2004cited by this paper
• GA-binding protein transcription factor: a review of GABP as an integrator of intracellular signaling and protein-protein interactions.

  2004influential reference
• Tissue-specific overexpression of the HSA21 gene GABPalpha: implications for DS.

  2004cited by this paper
• Targeted recruitment of a histone H4-specific methyltransferase by the transcription factor YY1.

  2003cited by this paper
• GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells.

  2003cited by this paper
• Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation.

  2003cited by this paper
• Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor

  2002cited by this paper
• Merlin—rapid analysis of dense genetic maps using sparse gene flow trees

  2002influential reference
• Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter.

  2001cited by this paper
• Rett syndrome: a surprising result of mutation in MECP2.

  2000cited by this paper
• Primer3 on the WWW for general users and for biologist programmers.

  2000cited by this paper
• The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA

  1998cited by this paper
• The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA.

  1998cited by this paper
• Regulation of mitochondrial biogenesis in brown adipose tissue: nuclear respiratory factor-2/GA-binding protein is responsible for the transcriptional regulation of the gene for the mitochondrial ATP synthase beta subunit.

  1998cited by this paper
• The prevalence of mental retardation: a critical review of recent literature

  1997cited by this paper
• Characterization of the Human Thrombopoietin Gene Promoter

  1997cited by this paper
• The transcriptional coactivators p300 and CBP are histone acetyltransferases.

  1996cited by this paper
• Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

  1995cited by this paper
• Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome).

  1995cited by this paper
• Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins.

  1992cited by this paper
• Citation for Published Item: Use Policy the Genetic Basis of Non-syndromic Intellectual Disability: a Review

  year unknowncited by this paper

• The methyltransferase-like proteins as core regulators of nucleic acid modifications and post-translation modification of proteins in disease pathogenesis and therapeutic implications

  2025cites this paper
• Message from the chief executive officer

  2025cites this paper
• Identification of a novel METTL23 gene variant in a patient with an intellectual development disorder: a literature review and case report

  2024cites this paper
• The neuron-specific IIS/FOXO transcriptome in aged animals reveals regulatory mechanisms of cognitive aging

  2024cites this paper
• Association Analysis of METTL23 Gene Polymorphisms with Reproductive Traits in Kele Pigs

  2024cites this paper
• METTL23 Variants and Patients With Normal-Tension Glaucoma.

  2024cites this paper
• Spectrum of genetic disorders and gene variants in the United Arab Emirates national population: insights from the CTGA database

  2023cites this paper
• VBASS enables integration of single cell gene expression data in Bayesian association analysis of rare variants

  2023cites this paper
• METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma

  2022cites this paper
• Entwined African and Asian genetic roots of medieval peoples of the Swahili coast

  2022cites this paper
• Active genic machinery for epigenetic RNA modifications in bees

  2021cites this paper
• Evolution of Methyltransferase-Like (METTL) Proteins in Metazoa: A Complex Gene Family Involved in Epitranscriptomic Regulation and Other Epigenetic Processes

  2021cites this paper
• Age-Associated DNA Methylation Patterns Are Shared Between the Hippocampus and Peripheral Blood Cells

  2020cites this paper
• Further delineation of METTL23‐associated intellectual disability

  2020cites this paper
• Exome sequencing revealed a novel homozygous METTL23 gene mutation leading to familial mild intellectual disability with dysmorphic features.

  2020cites this paper
• Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences

  2020cites this paper
• Two Cases of Recessive Intellectual Disability Caused by NDST1 and METTL23 Variants

  2020influential citation
• Protein lysine methylation is involved in modulating the response of sensitive and tolerant Arabidopsis species to cadmium stress

  2019cites this paper
• Evidence for the involvement of protein lysine methylation in the response of sensitive and tolerant Arabidopsis species to cadmium stress

  2019cites this paper
• Tensor Decomposition-Based Unsupervised Feature Extraction Applied to Single-Cell Gene Expression Analysis

  2019cites this paper
• Genome-Wide Identification and Transcriptional Expression of the METTL21C Gene Family in Chicken

  2019cites this paper
• Bi-allelic Variants in METTL5 Cause Autosomal-Recessive Intellectual Disability and Microcephaly.

  2019cites this paper
• Protein lysine methylation contributes to modulating the response of sensitive and tolerant Arabidopsis species to cadmium stress.

  2019cites this paper
• Spotlight into some Abnormalities of Human Chromosome in Saudi Arabia

  2018cites this paper
• Exploring gene expression biomarker candidates for neurobehavioral impairment from total sleep deprivation

  2018cites this paper
• Gene Expression Biomarkers for Neurobehavioral Impairment From Total Sleep Deprivation

  2017cites this paper
• GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma

  2017cites this paper
• METTL21B Is a Novel Human Lysine Methyltransferase of Translation Elongation Factor 1A: Discovery by CRISPR/Cas9 Knockout*

  2017cites this paper
• Characterization of Human Lysine-specific Protein Methyltransferases in the METTL 21 Subgroup Thesis for the degree of Philosophiae Doctor

  2017influential citation
• Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle

  2017cites this paper
• Jmjd6, a JmjC Dioxygenase with Many Interaction Partners and Pleiotropic Functions

  2017cites this paper
• Blood-Based Biomarkers Thrombopoietin is associated with d ’ s intercept , and only in Non-Hispanic Whites

  2016cites this paper
• Protein lysine methylation by seven-β-strand methyltransferases.

  2016cites this paper
• Thrombopoietin is associated with δ's intercept, and only in Non-Hispanic Whites

  2016cites this paper
• The Molecular Genetics of Autosomal Recessive Nonsyndromic Intellectual Disability: a Mutational Continuum and Future Recommendations

  2016cites this paper
• The activity of a yeast Family 16 methyltransferase, Efm2, is affected by a conserved tryptophan and its N‐terminal region

  2016cites this paper
• Identification and characterization of novel evolutionarily conserved protein methyltransferases

  2015cites this paper
• Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice

  2015cites this paper
• Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay

  2015cites this paper
• Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination.

  2015cites this paper
• Lysine Methylation of Non-Histone Proteins

  2015cites this paper
• A Novel Whole Exon Deletion in WWOX Gene Causes Early Epilepsy, Intellectual Disability and Optic Atrophy

  2014cites this paper
• The lysine multi-switch: the impact of lysine methylation on transcription factor properties

  2014influential citation
• Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects

  2014cites this paper
• Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability

  2014influential citation
• Genetics and genomic medicine in Saudi Arabia

  2014cites this paper
• Identification and Characterization of a Novel Evolutionarily Conserved Lysine-specific Methyltransferase Targeting Eukaryotic Translation Elongation Factor 2 (eEF2)*

  2014cites this paper