Effects of different phenotypes of hyperlipoproteinemia and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation in humans.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  1995-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1161/01.ATV.15.8.1064PMID 7627697
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Verapamil

  2012cited by this paper
• Effects of bezafibrate on hepatic cholesterol metabolism

  2005cited by this paper
• Drug treatment of dyslipoproteinemia.

  1994cited by this paper
• Effect of aging on cholesterol 7 alpha-hydroxylation in humans.

  1993cited by this paper
• Regulation of bile acid synthesis in humans: Effect of treatment with bile acids, cholestyramine or simvastatin on cholesterol 7α‐hydroxylation rates in vivo

  1991cited by this paper
• Regulation of bile acid synthesis

  1991cited by this paper
• Effect of gemfibrozil administration on biliary lipid secretion in hyperlipidemic patients. A crossover study with clofibrate.

  1990cited by this paper
• Low density lipoprotein receptor-binding activity in human tissues: quantitative importance of hepatic receptors and evidence for regulation of their expression in vivo.

  1990cited by this paper
• Familial combined hyperlipidemia workshop

  1989cited by this paper
• Biliary lipid secretion in patients with heterozygous familial hypercholesterolemia and combined hyperlipidemia. Influence of bezafibrate and fenofibrate.

  1988cited by this paper
• Bile acid metabolism in heterozygous familial hypercholesterolaemia: a study comparing affected and unaffected siblings of four kindreds

  1988cited by this paper
• Effects of fibric acid derivatives on biliary lipid composition.

  1987cited by this paper
• Role of receptor-independent low density lipoprotein transport in the maintenance of tissue cholesterol balance in the normal and WHHL rabbit.

  1987cited by this paper
• Bile acid metabolism in hereditary forms of hypertriglyceridemia: evidence for an increased synthesis rate in monogenic familial hypertriglyceridemia.

  1987cited by this paper
• Effects of bezafibrate on apolipoprotein B metabolism in type III hyperlipoproteinemic subjects.

  1986cited by this paper
• In vivo evaluation of cholesterol 7 alpha-hydroxylation in humans: effect of disease and drug treatment.

  1986cited by this paper
• Effect of gemfibrozil on biliary lipid metabolism in normolipemic subjects.

  1985cited by this paper
• Influence of Gemfibrozil and Clofibrate on Metabolism of Cholesterol and Plasma Triglycerides in Man

  1984cited by this paper
• Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man.

  1984cited by this paper
• Gallstone dissolution and the cholesterol-bile acid-lipoprotein axis. Propitious effects of ursodeoxycholic acid

  1984cited by this paper
• Gallstone dissolution and the cholesterol--bile acid--lipoprotein axis. Propitious effects of ursodeoxycholic acid.

  1984cited by this paper
• Cholesterol and Bile Acid Synthesis in Two Families with Homozygous and Heterozygous Hypercholesterolemia

  1984cited by this paper
• Regulation of cholesterol metabolism in man and in other species

  1984cited by this paper
• Treatment of familial hypercholesterolemia by portacaval anastomosis: effect on cholesterol metabolism and pool sizes.

  1983cited by this paper
• Plasma lipoproteins in familial combined hyperlipidemia and monogenic familial hypertriglyceridemia.

  1983cited by this paper
• Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia.

  1981cited by this paper
• Elevated cholesterol and bile acid synthesis in an adult patient with homozygous familial hypercholesterolemia. Reduction by a high glucose diet.

  1981cited by this paper
• Hepatic cholesterol and bile acid metabolism in subjects with gallstones: comparative effects of short erm feeding of chenodeoxycholic and ursodeoxycholic acid.

  1980cited by this paper
• Very low density lipoprotein overproduction in genetic forms of hypertriglyceridaemia

  1980cited by this paper
• Cholesterol 7 alpha-hydroxylase.

  1977cited by this paper
• Familial hypercholesterolemia: A genetic defect in the low-density lipoprotein receptor.

  1976cited by this paper
• Rat-liver cholesterol 7 alpha-hydroxylase. 1. Development of a new assay based on the enzymic exchange of the tritium located on the 7 alpha position of the substrate.

  1975cited by this paper
• Bile acid kinetics in relation to sex, serum lipids, body weights, and gallbladder disease in patients with various types of hyperlipoproteinemia;.

  1974cited by this paper
• Effects of clofibrate and of an estrogen-progestin combination on fasting biliary lipids and cholic acid kinetics in man.

  1974cited by this paper
• Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia.

  1973cited by this paper
• The Effect of Clofibrate on the Elimination of Cholesterol as Bile Acids in Patients with Hyperlipoproteinaemia Type II and IV

  1973cited by this paper
• Stereospecific Syntheses of the 7-Deuterio- and 7-Tritiocholesterols. The Mechanism of Enzyme-catalyzed Hydroxylation at a Saturated Carbon Atom

  1959cited by this paper

• Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol

  2020cites this paper
• Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport.

  2019cites this paper
• Activation of PPAR&agr; decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion

  2018cites this paper
• Glyphosate, pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies

  2015cites this paper
• Integrated physiology and systems biology of PPARα

  2014cites this paper
• Increased appearance rate of 27-hydroxycholesterol in vivo in hypercholesterolemia: a possible compensatory mechanism.

  2012cites this paper
• The Use of Stable and Radioactive Sterol Tracers as a Tool to Investigate Cholesterol Degradation to Bile Acids in Humans in Vivo

  2012influential citation
• Peroxisome Proliferator-Activated Receptor Alpha Target Genes

  2010cites this paper
• Regulation of Bile Acid and Cholesterol Metabolism by PPARs

  2009cites this paper
• Nuclear receptors as potential molecular targets in cholesterol accumulation conditions: insights from evidence on hepatic cholesterol degradation and gallstone disease in humans.

  2008cites this paper
• Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT).

  2008cites this paper
• Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.

  2008cites this paper
• Therapeutic Effects of Fibrates in Postprandial Lipemia

  2008cites this paper
• PPARalpha and dyslipidemia.

  2007cites this paper
• Changes in bile acid synthesis in gallstone disease: Cause, consequence, or neither?

  2007cites this paper
• PPARα and dyslipidemia

  2007cites this paper
• Reply:

  2007cites this paper
• Decreased hepatic expression of PPAR‐γ coactivator‐1 in cholesterol cholelithiasis

  2006cites this paper
• Nutrition and Disease Fish Oil Increases Bile Acid Synthesis in Male Patients with Hypertriglyceridemia 1

  2006cites this paper
• Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.

  2006cites this paper
• Activation of the rat scavenger receptor class B type I gene by PPARalpha.

  2006cites this paper
• Fenofibrate Induces a Novel Degradation Pathway for Scavenger Receptor B-I Independent of PDZK1*

  2005cites this paper
• The gene encoding the human ileal bile acid-binding protein (I-BABP) is regulated by peroxisome proliferator-activated receptors.

  2005cites this paper
• Differential regulation of cytosolic and peroxisomal bile acid amidation by PPAR activation favors the formation of unconjugated bile acids

  2004cites this paper
• [Peroxisome proliferator-activated receptors (PPARs) in obesity and insulin resistance development].

  2004cites this paper
• Differential regulation of cytosolic and peroxisomal bile acid amidation by PPARα activation favors the formation of unconjugated bile acids Published, JLR Papers in Press, March 16, 2004. DOI 10.1194/jlr.M300291-JLR200

  2004cites this paper
• Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients

  2004cites this paper
• Peroxisome proliferator-activated receptor alpha target genes.

  2004cites this paper
• PPAR alpha, fibrates, lipid metabolism and inflammation.

  2004cites this paper
• Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes.

  2004cites this paper
• Los fibratos modifican la expresión hepática de colesterol 7-α-hidroxilasa, MDR3 y ABCG5 en pacientes con colelitiasis

  2004cites this paper
• Influence of newly synthesized cholesterol on bile acid synthesis during chronic inhibition of bile acid absorption

  2003cites this paper
• Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.

  2003cites this paper
• Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liver

  2002cites this paper
• PPARs: Transcription Factors Controlling Lipid and Lipoprotein Metabolism

  2002cites this paper
• Pleiotropic Actions of Peroxisome Proliferator-Activated Receptors in Lipid Metabolism and Atherosclerosis

  2002cites this paper
• Fibrates and coronary heart disease reduction in diabetes

  2002cites this paper
• Bile acid regulation of gene expression: roles of nuclear hormone receptors.

  2002cites this paper
• Fibrates Suppress Bile Acid Synthesis via Peroxisome Proliferator–Activated Receptor-&agr;–Mediated Downregulation of Cholesterol 7&agr;-Hydroxylase and Sterol 27-Hydroxylase Expression

  2001cites this paper
• Increase in hepatic expression of SREBP-2 by gemfibrozil administration to rats.

  2001cites this paper
• Antagonism of the Actions of Peroxisome Proliferator-activated Receptor-α by Bile Acids*

  2001cites this paper
• Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice

  2001cites this paper
• Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids.

  2001cites this paper
• Peroxisome proliferator-activated receptor a (PPAR a ) and agonist inhibit cholesterol 7 a -hydroxylase gene ( CYP7A1 ) transcription

  2000cites this paper
• The Murine and Human Cholesterol 7α-Hydroxylase Gene Promoters Are Differentially Responsive to Regulation by Fatty Acids Mediated via Peroxisome Proliferator-activated Receptor α*

  2000cites this paper
• The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.

  2000cites this paper
• Peroxisome proliferator-activated receptor alpha (PPARalpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription.

  2000cites this paper
• Regulation of bile acid synthesis.

  1998cites this paper
• Effect of hypolipidemic drugs on key enzyme activities related to lipid metabolism in normolipidemic rabbits.

  1998cites this paper
• Relationship between the serum concentration of 7 alpha-hydroxycholesterol and fecal bile acid excretion in humans.

  1996cites this paper
• AHA consensus panel statement. Preventing heart attack and death in patients with coronary disease. The Secondary Prevention Panel.

  1995cites this paper
• Regulation of bile acid synthesis in humans: studies on cholesterol 7 alpha-hydroxylation in vivo.

  1995cites this paper