Landscape, bifurcations, geometry for development

P. François,Laurent Jutras-Dubé

Published 2018 in Current Opinion in Systems Biology

ABSTRACT

Abstract We review recent advances in the mathematical modelling of development, with a special focus on the concepts from non linear physics applied to cellular differentiation and metazoan segmentation. Those models suggest that geometric descriptions with few parameters are sufficient to capture many of the non trivial aspects of development. We also describe open questions such as the connections to machine learning, from network enumeration/evolution to landscape reconstruction.

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REFERENCES

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