Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  American Journal of Physiology. Heart and Circulatory Physiology

• Publication date

  2000-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPHEART.2000.279.5.H2414PMID 11045979
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction.

  1999cited by this paper
• Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function

  1999cited by this paper
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• A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity.

  1998cited by this paper
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  1998cited by this paper
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• Beta-tropomyosin overexpression induces severe cardiac abnormalities.

  1998cited by this paper
• β-Tropomyosin Overexpression Induces Severe Cardiac Abnormalities

  1998cited by this paper
• Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.

  1997cited by this paper
• Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility.

  1997cited by this paper
• Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.

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  1996cited by this paper
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  1996cited by this paper
• Exchange of - for -Tropomyosin in Hearts of Transgenic Mice Induces Changes in Thin Filament Response to Ca, Strong Cross-bridge Binding, and Protein Phosphorylation (*)

  1996cited by this paper
• Clinical implications of hypertrophic cardiomyopathy associated with mutations in the alpha-tropomyosin gene.

  1996cited by this paper
• Altered interactions among thin filament proteins modulate cardiac function.

  1996cited by this paper
• Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Molecular and Physiological Effects of Overexpressing Striated Muscle β-Tropomyosin in the Adult Murine Heart (*)

  1995cited by this paper
• Novel missense mutation in alpha-tropomyosin gene found in Japanese patients with hypertrophic cardiomyopathy.

  1995cited by this paper
• Recent advances in the molecular genetics of hypertrophic cardiomyopathy.

  1995cited by this paper
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  1993cited by this paper
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  1979cited by this paper
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  1977cited by this paper
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  1976cited by this paper
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  2013cites this paper
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