Geometrical guidance and trapping transition of human sperm cells.

The guidance of human sperm cells under confinement in quasi-2D microchambers is investigated using a purely physical method to control their distribution. Transport property measurements and simulations are performed with diluted sperm populations, for which effects of geometrical guidance and concentration are studied in detail. In particular, a trapping transition at convex angular wall features is identified and analyzed. We also show that highly efficient microratchets can be fabricated by using curved asymmetric obstacles to take advantage of the spermatozoa specific swimming strategy.

• Publication year

  2014

• Venue

  Physical review. E, Statistical, nonlinear, and soft matter physics

• Publication date

  2014-01-11

• Fields of study

  Medicine, Physics

• Identifiers
  DOI 10.1103/PhysRevE.89.032720arXiv 1401.2551PMID 24730887
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2011cited by this paper
• Comment on the article by J. Elgeti, U. B. Kaupp, and G. Gompper: hydrodynamics of sperm cells near surfaces.

  2011cited by this paper
• Enhanced diffusion due to active swimmers at a solid surface.

  2010cited by this paper
• Hydrodynamics of sperm cells near surfaces.

  2010cited by this paper
• Accumulation of microswimmers near a surface mediated by collision and rotational Brownian motion.

  2009cited by this paper
• Bacterial growth and motility in sub-micron constrictions

  2009cited by this paper
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  2008cited by this paper
• Hydrodynamic attraction of swimming microorganisms by surfaces.

  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
• Rectification of swimming bacteria and self-driven particle systems by arrays of asymmetric barriers.

  2007cited by this paper
• A Wall of Funnels Concentrates Swimming Bacteria

  2007cited by this paper
• Lab on a chip

  2004cited by this paper
• Motility of spermatozoa at surfaces.

  2003cited by this paper
• How spermatozoa come to be confined to surfaces.

  2003cited by this paper
• Passively driven integrated microfluidic system for separation of motile sperm.

  2003cited by this paper
• Dictyostelium: Cell Motility and the Cytoskeleton

  2001cited by this paper
• Three-dimensional tracking of motile bacteria near a solid planar surface.

  1995cited by this paper
• Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques.

  1988cited by this paper
• Observations on the response of human spermatozoa to gravity, boundaries and fluid shear.

  1984cited by this paper
• Reproduction

  1975cited by this paper
• The Physics of Fluids

  1958cited by this paper

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  2025cites this paper
• Hydrodynamic interactions of two nearby flagellated microswimmers.

  2025cites this paper
• Geometry of obstructed pathway regulates upstream navigational pattern of sperm population.

  2025cites this paper
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  2024cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Dynamics of self-propelled particles under strong confinement.

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