HLA-DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self-perpetuating arthritis.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Arthritis & Rheumatism

• Publication date

  2009-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/art.25005PMID 19950279PMCID PMC2828865
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Emergence of chronic Lyme arthritis: Putting the breaks on CD28 costimulation

  2009cited by this paper
• Persistent arthritis in Borrelia burgdorferi-infected HLA-DR4-positive CD28-negative mice post-antibiotic treatment.

  2008cited by this paper
• HLA class II transgenic mice mimic human inflammatory diseases.

  2008cited by this paper
• Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis

  2008cited by this paper
• Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis.

  2008cited by this paper
• High levels of inflammatory chemokines and cytokines in joint fluid and synovial tissue throughout the course of antibiotic-refractory lyme arthritis.

  2007cited by this paper
• CD28 Deficiency Exacerbates Joint Inflammation upon Borrelia burgdorferi Infection, Resulting in the Development of Chronic Lyme Arthritis1

  2007cited by this paper
• Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex.

  2006cited by this paper
• Therapy for Lyme arthritis: strategies for the treatment of antibiotic-refractory arthritis.

  2006cited by this paper
• MHC class II proteins and disease: a structural perspective

  2006cited by this paper
• Gene Expression Profiling Reveals Unique Pathways Associated with Differential Severity of Lyme Arthritis1

  2006cited by this paper
• Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide

  2006cited by this paper
• Well differentiated thyroid carcinoma is associated with human lymphocyte antigen D‐related 11 in Eastern Hungarians

  2005cited by this paper
• Elucidation of Lyme arthritis

  2004cited by this paper
• Binding of outer surface protein A and human lymphocyte function-associated antigen 1 peptides to HLA-DR molecules associated with antibiotic treatment-resistant Lyme arthritis.

  2003cited by this paper
• T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MRL/lpr mice

  2003cited by this paper
• T cell recognition and therapeutic effect of a phosphorylated synthetic peptide of the 70K snRNP protein administered in MR/lpr mice.

  2003cited by this paper
• HLA class II genotypes in Mexican Mestizo patients with myasthenia gravis

  2003cited by this paper
• Gamma Interferon Inhibits Production of Anti-OspA Borreliacidal Antibody In Vitro

  2002cited by this paper
• Development of autoimmunity in Lyme arthritis.

  2002cited by this paper
• Autoimmune disease: why and where it occurs

  2001cited by this paper
• Identification of HLA-class-II-restricted epitopes of autoantigens in transgenic mice.

  2000cited by this paper
• Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers.

  2000cited by this paper
• Lack of Borrelia burgdorferi DNA in synovial samples from patients with antibiotic treatment-resistant Lyme arthritis.

  1999cited by this paper
• MHC structure and autoimmune T cell repertoire development.

  1999cited by this paper
• Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferi.

  1999cited by this paper
• T helper 1 response is dominant and localized to the synovial fluid in patients with Lyme arthritis.

  1998cited by this paper
• Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis.

  1998cited by this paper
• T-helper-cell cytokines in the early evolution of murine Lyme arthritis

  1997cited by this paper
• Sequencing of HLA class II genes based on the conserved diversity of the non-coding regions: sequencing based typing of HLA-DRB genes.

  1997cited by this paper
• HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis

  1996cited by this paper
• Role of IL-4 and IFN-gamma in modulation of immunity to Borrelia burgdorferi in mice.

  1995cited by this paper
• Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association

  1995cited by this paper
• Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme disease

  1995cited by this paper
• T helper phenotype and genetic susceptibility in experimental Lyme disease

  1995cited by this paper
• Treatment of Lyme arthritis.

  1994cited by this paper
• Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning

  1994cited by this paper
• Diverse Lyme disease spirochetes bind integrin alpha IIb beta 3 on human platelets

  1994cited by this paper
• Implication of HLA-DR residues at positions 67, 71, and 86 in interaction between HLA-DR11 and peptide HA306-320.

  1993cited by this paper
• Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets.

  1993cited by this paper
• Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi

  1993cited by this paper
• Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis

  1991cited by this paper

• Aspects of the Immunopathogenesis of Lyme Arthritis

  2025cites this paper
• Proposed Immunopathogenetic Mechanisms Underlying Lyme Arthritis.

  2024cites this paper
• Lyme Arthritis: A 50-Year Journey.

  2024cites this paper
• Genome-wide DNA Methylation Profiling in Lyme Neuroborreliosis Reveals Altered Methylation Patterns of HLA Genes

  2023cites this paper
• The Genetic Predisposition of Human and Laboratory Animals to Different Infections Transmitted by Ixodid Ticks

  2022cites this paper
• Lyme-Arthritis

  2022cites this paper
• Case Report: PANDAS and Persistent Lyme Disease With Neuropsychiatric Symptoms: Treatment, Resolution, and Recovery

  2021cites this paper
• Lyme arthritis: linking infection, inflammation and autoimmunity

  2021cites this paper
• A Review of Post-treatment Lyme Disease Syndrome and Chronic Lyme Disease for the Practicing Immunologist

  2021cites this paper
• Structure-Based Design of Diagnostics and Vaccines for Lyme Disease.

  2021cites this paper
• References

  2020cites this paper
• LIVING LYME

  2020cites this paper
• Lyme Disease Outside In

  2020cites this paper
• MAPPING THE LYME DISEASE CONTROVERSY

  2020cites this paper
• DIAGNOSING AND TREATING LYME

  2020cites this paper
• 5. Lyme Disease, Evidence-Based Medicine, and the Biopolitics of Truthmaking

  2020cites this paper
• Notes

  2020cites this paper
• Through Lyme’s Looking Glass

  2020cites this paper
• Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses.

  2020cites this paper
• PREVENTING LYME

  2020cites this paper
• Investigating disease severity in an animal model of concurrent babesiosis and Lyme disease.

  2019cites this paper
• Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs

  2019cites this paper
• Lyme Disease and Dementia, Alzheimer, Parkinson, Autism, an Easy Way to Destroy your Brain

  2018cites this paper
• 34 – Lyme Disease Vaccines

  2018cites this paper
• Chapter 29 – Experimental Models for Rheumatoid Arthritis

  2017cites this paper
• Effects of 670 Nm and 830 Nm Light on the Immune Response to Borrelia Burgdorferi

  2015cites this paper
• Evolutionary Aspects of Emerging Lyme Disease in Canada

  2015cites this paper
• Complex Population Structure of Borrelia burgdorferi in Southeastern and South Central Canada as Revealed by Phylogeographic Analysis

  2014cites this paper
• Tick-specific borrelial antigens appear to be upregulated in American but not European patients with Lyme arthritis, a late manifestation of Lyme borreliosis.

  2013cites this paper
• Natural killer cells and natural killer T cells in Lyme arthritis

  2013cites this paper
• Natural killer cells and natural killer T cells in

  2013cites this paper
• 52 – Lyme disease vaccines

  2013cites this paper
• 28 – Experimental Models for Rheumatoid Arthritis

  2013cites this paper
• Musculoskeletal Features of Lyme Disease: Understanding the Pathogenesis of Clinical Findings Helps Make Appropriate Therapeutic Choices

  2011cites this paper
• Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis.

  2011cites this paper
• Infectious arthritis and immune dysregulation: lessons from Lyme disease

  2010cites this paper
• Treg cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive Lyme arthritis.

  2010cites this paper