2‐deoxyglucose inhibits chemotheapeutic drug‐induced apoptosis in human monocytic leukemia U937 cells ith inhibition of c‐Jun N‐terminal kinase 1/stress‐activated protein kinase activation

No abstract is available for this paper.

• Publication year

  1998

• Venue

  International Journal of Cancer

• Publication date

  1998-03-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/(SICI)1097-0215(19980330)76:1<86::AID-IJC14>3.0.CO;2-EPMID 9533766
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

  1997cited by this paper
• Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

  1997cited by this paper
• Actin cleavage by CPP-32/apopain during the development of apoptosis

  1997cited by this paper
• c-Jun NH2-terminal Kinase-mediated Activation of Interleukin-1β Converting Enzyme/CED-3-like Protease during Anticancer Drug-induced Apoptosis*

  1997cited by this paper
• Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis.

  1997cited by this paper
• Glucose‐regulated stresses induce resistance to camptothecin in human cancer cells

  1996cited by this paper
• FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

  1996cited by this paper
• Glucose-regulated stresses cause decreased expression of cyclin D1 and hypophosphorylation of retinoblastoma protein in human cancer cells.

  1996cited by this paper
• Activation of the CPP32 Apoptotic Protease by Distinct Signaling Pathways with Differential Sensitivity to Bcl-xL*

  1996cited by this paper
• Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

  1996cited by this paper
• CPP32/Apopain Is a Key Interleukin 1 Converting Enzyme-like Protease Involved in Fas-mediated Apoptosis (*)

  1996cited by this paper
• Synergistic Effects of Insulin and Phorbol Ester on Mitogen-activated Protein Kinase in Rat-1 HIR Cells (*)

  1996cited by this paper
• Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

  1996cited by this paper
• Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

  1996cited by this paper
• 2-Deoxy-D-glucose enhances sensitivity of human histiocytic lymphoma U937 cells to apoptosis induced by tumor necrosis factor.

  1995cited by this paper
• Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells.

  1995cited by this paper
• Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II.

  1995cited by this paper
• Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis.

  1995cited by this paper
• Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

  1995cited by this paper
• Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

  1995cited by this paper
• Resistance to antitumor agent-induced apoptosis in a mutant of human myeloid leukemia U937 cells.

  1994cited by this paper
• JNK is involved in signal integration during costimulation of T lymphocytes.

  1994cited by this paper
• 10,11-Methylenedioxycamptothecin, a topoisomerase I inhibitor of increased potency: DNA damage and correlation to cytotoxicity in human colon carcinoma (HT-29) cells.

  1990cited by this paper
• Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

  1989cited by this paper
• Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA.

  1987cited by this paper
• DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II.

  1986cited by this paper
• Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

  1984cited by this paper
• Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

  1980cited by this paper
• Shrinkage necrosis: A distinct mode of cellular death

  1971cited by this paper

• Structure and Metabolically Oriented Efficacy of Fucoidan from Brown Alga Sargassum muticum in the Model of Colony Formation of Melanoma and Breast Cancer Cells

  2023cites this paper
• Improving breast cancer therapy through oestrone analogue and glycolysis inhibitor synergism

  2017cites this paper
• Caloric restriction mimetic 2-deoxyglucose alleviated lethal liver injury induced by lipopolysaccharide/D-galactosamine in mice.

  2015cites this paper
• Ursolic Acid Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Cell Lines U251 by Suppressing TGF‐β1/miR‐21/PDCD4 Pathway

  2012cites this paper
• Dying for Something to Eat: How Cells Respond to Starvation

  2011cites this paper
• Sugar-free approaches to cancer cell killing

  2011cites this paper
• Mecanismos moleculares de la muerte celular inducida por privación de glucosa

  2010cites this paper
• Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells.

  2009cites this paper
• The Complexity of the HIF-1-Dependent Hypoxic Response in Breast Cancer Presents Multiple Avenues for Therapeutic Intervention

  2009cites this paper
• marine drugs

  2008cites this paper
• Can radiation-induced apoptosis be modulated by inhibitors of energy metabolism?

  2007influential citation
• Does the tumor microenvironment influence radiation-induced apoptosis?

  2006cites this paper
• Acute toxicity and cardio-respiratory effects of 2-deoxy-D-glucose: a promising radio sensitiser.

  2006cites this paper
• Mitomycin-C induces the apoptosis of human Tenon's capsule fibroblast by activation of c-Jun N-terminal kinase 1 and caspase-3 protease.

  2005cites this paper
• Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)‐induced apoptosis in human glioblastoma cells

  2005cites this paper
• Two-deoxyglucose as an anti-metabolite in human carcinoma cell line RPMI-2650 and drug-resistant variants.

  2004cites this paper
• Mitochondrial aggregation precedes cytochrome c release from mitochondria during apoptosis

  2003cites this paper
• Diltiazem Reduces Apoptosis in Rat Hepatocytes Subjected to Warm Hypoxia-Reoxygenation

  2002cites this paper
• Analysis of cellular sensitization with cisplatin-induced apoptosis by glucose-starved stress in cisplatin-sensitive and -resistant A431 cell line.

  2001cites this paper
• Differential involvement of caspases in hydroquinone-induced apoptosis in human leukemic hl-60 and jurkat cells.

  2001cites this paper
• MEK and p38MAPK inhibitors potentiate TNF-alpha induced apoptosis in U937 cells.

  2001cites this paper
• Protein kinase activation by warm and cold hypoxia‐reoxygenation in primary‐cultured rat hepatocytes–JNK1/SAPK1 involvement in apoptosis

  2000cites this paper
• Inhibitors of the MAPK pathway

  2000cites this paper
• Downregulation of JNK/SAPK activity is associated with the cross-resistance to P-glycoprotein-unrelated drugs in multidrug-resistant FM3A/M cells overexpressing P-glycoprotein.

  2000cites this paper
• Induction of apoptosis by dexrazoxane (ICRF-187) through caspases in the absence of c-jun expression and c-Jun NH2-terminal kinase 1 (JNK1) activation in VM-26-resistant CEM cells.

  1999cites this paper
• Merbarone, a catalytic inhibitor of DNA topoisomerase II, induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.

  1999cites this paper
• Effect of cellular ATP depletion on topoisomerase II poisons. Abrogation Of cleavable-complex formation by etoposide but not by amsacrine.

  1999cites this paper