Exposure to polymers reverses inhibition of pulmonary surfactant by serum, meconium, or cholesterol in the captive bubble surfactometer.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biophysical Journal

• Publication date

  2012-10-03

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.bpj.2012.08.024PMID 23062337PMCID PMC3471484
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008influential reference
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  2008cited by this paper
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  1998influential reference
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  1992cited by this paper
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  1989cited by this paper

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