Role of calpain in spinal cord injury: Increased calpain immunoreactivity in rat spinal cord after impact trauma

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Neurochemical Research

• Publication date

  1996-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF02527708PMID 8734437
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of calpain in spinal cord injury: increased mcalpain immunoreactivity in spinal cord after compression injury in the rat.

  1995cited by this paper
• Neurofilament 68 and Neurofilament 200 Protein Levels Decrease After Traumatic Brain Injury

  1994influential reference
• Calpain activity in adult and aged human brain regions

  1994cited by this paper
• Postischemic Administration of AK275, a Calpain Inhibitor, Provides Substantial Protection against Focal Ischemic Brain Damage

  1994cited by this paper
• Experimental acute traumatic injury of the adult rat spinal cord by a subdural inflatable balloon: Methodology, behavioral analysis, and histopathology

  1992cited by this paper
• Lectin staining of cultured CNS microglia.

  1992cited by this paper
• Macrophages and Astroglial Interactions in Repair to Brain Injury a

  1992cited by this paper
• Inhibition of proteolysis protects hippocampal neurons from ischemia.

  1991cited by this paper
• Calpain II in rat peripheral nerve.

  1991cited by this paper
• Calcium‐activated neutral proteinase (CANP; calpain) activity in Schwann cells: Immunofluorescence localization and compartmentation of μ‐ and mCANP

  1991cited by this paper
• Neuropathological Changes and Neurological Function After Spinal Cord Compression in the Rat

  1990cited by this paper
• Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats.

  1990cited by this paper
• The regional and subcellular distribution of calcium activated neutral proteinase (CANP) in the bovine central nervous system

  1989cited by this paper
• Therapeutic Model for Experimental Spinal Cord Injury in the Rat: I. Mortality and Motor Deficit

  1987cited by this paper
• Calcium-Activated Mediators of Secondary Injury in the Spinal Cord

  1986cited by this paper
• Proteolytic enzymes in experimental spinal cord injury.

  1986cited by this paper
• Role of Lipid Peroxidation in Post-Traumatic Spinal Cord Degeneration: A Review

  1986cited by this paper
• Distribution of calpains I and II in rat brain

  1986cited by this paper
• Fodrin degradation by calcium-activated neutral proteinase (CANP) in retinal ganglion cell neurons and optic glia: preferential localization of CANP activities in neurons

  1986cited by this paper
• Distribution of calpain I, an enzyme associated with degenerative activity, in rat brain.

  1985cited by this paper
• Biochemistry of the Spinal Cord

  1985cited by this paper
• Calcium-dependent proteinases and specific inhibitors: calpain and calpastatin.

  1984cited by this paper
• Changes in Myelin and Axonal Proteins in CaCl2-Induced Myelopathy in Rat Spinal Cord

  1984cited by this paper
• Effects of multi-dose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilament degradation and energy metabolism.

  1984cited by this paper
• Extracellular calcium activity in the injured spinal cord.

  1983cited by this paper
• Extracellular calcium ionic activity in experimental spinal cord contusion.

  1982cited by this paper
• Degradation of cytoskeletal proteins in experimental spinal cord injury

  1982cited by this paper
• Ca2+-accumulation in experimental spinal cord trauma.

  1981cited by this paper
• The effects of spinal cord trauma on myelin.

  1980cited by this paper
• Calcium-dependent degradation of mammalian neurofilaments by soluble tissue factor(s) from rat spinal cord.

  1980cited by this paper
• Pathology of experimental spinal cord trauma. I. The necrotic lesion as a function of vascular injury.

  1978cited by this paper
• Pathology of experimental spinal cord trauma. I. The necrotic lesion as a function of vascular injury.

  1978cited by this paper
• Changes in myelin following trauma of the spinal cord in monkeys.

  1973cited by this paper
• REMARKS ON THE HISTOPATHOLOGICAL CHANGES IN THE SPINAL CORD DUE TO IMPACT. AN EXPERIMENTAL STUDY

  1914cited by this paper

• The Temporal and Spatial Distribution Patterns of Necrotic and Apoptotic Cells in and Around the Spinal Cord Injury Site

  2025cites this paper
• Calpains at the Crossroads of Spinal Cord Physiology, Plasticity, and Pathology

  2025cites this paper
• Knockdown of calpain1 in lumbar motoneurons reduces spasticity after spinal cord injury in adult rats

  2024cites this paper
• Role of chloride cotransporters in the development of spasticity and neuropathic pain after spinal cord injury

  2020cites this paper
• Time-dependent microglia and macrophages response after traumatic spinal cord injury in rat: a systematic review.

  2020cites this paper
• Melatonin, a calpain inhibitor in the central nervous system: Current status and future perspectives

  2018cites this paper
• Cleavage of Na+ channels by calpain increases persistent Na+ current and promotes spasticity after spinal cord injury

  2016cites this paper
• Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy.

  2015cites this paper
• Receptor for Advanced Glycation End Products (RAGE) and Its Ligands: Focus on Spinal Cord Injury

  2014cites this paper
• Targeting reactive astrogliosis by novel biotechnological strategies.

  2012cites this paper
• A Calpain Inhibitor Enhances the Survival of Schwann Cells In Vitro and after Transplantation into the Injured Spinal Cord

  2010cites this paper
• Calpains: attractive targets for the development of synthetic inhibitors.

  2010cites this paper
• 25 Estrogen as a Promising Multi-Active Agent for the Treatment of Spinal Cord Injury

  2009cites this paper
• Calpain inhibitor AK 295 inhibits calpain-induced apoptosis and improves neurologic function after traumatic spinal cord injury in rats.

  2009cites this paper
• Therapeutic efficacy of SJA6017, a calpain inhibitor, in rat spinal cord injury.

  2008cites this paper
• Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model.

  2007cites this paper
• Calpain inhibition: a therapeutic strategy targeting multiple disease states.

  2006cites this paper
• Degradation of Spectrin via Calpains in the Ventral Horn after Transient Spinal Cord Ischemia in Rabbits

  2006cites this paper
• Higher Calpastatin Levels Correlate with Resistance to Calpain-Mediated Proteolysis and Neuronal Apoptosis in Juvenile Rats after Spinal Cord Injury

  2004cites this paper
• CHARACTERIZATION OF CATHEPSIN B mRNA AND PROTEIN EXPRESSION, ENZYMATIC ACTIVITY AND CELLULAR LOCALIZATION FOLLOWING CONTUSION SPINAL CORD INJURY IN RATS

  2004cites this paper
• Calpain inhibition protects against Taxol-induced sensory neuropathy.

  2003influential citation
• Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats

  2003influential citation
• Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors.

  2003cites this paper
• Selective release of calpain produced alphalI-spectrin (alpha-fodrin) breakdown products by acute neuronal cell death.

  2002cites this paper
• Treatment of spinal cord impact injury in the rat with transforming growth factor-beta.

  2002cites this paper
• The gene for slow Wallerian degeneration (Wld(s)) is also protective against vincristine neuropathy.

  2001cites this paper
• Calpain activity and expression increased in activated glial and inflammatory cells in penumbra of spinal cord injury lesion

  2000cites this paper
• Rapid increase in immunoreactivity to GFAP in astrocytes in vitro induced by acidic pH is mediated by calcium influx and calpain I.

  2000cites this paper
• Cytoskeletal Disruption Following Contusion Injury to the Rat Spinal Cord

  2000cites this paper
• Pretreatment with Calpain Inhibitor CEP‐4143 Inhibits Calpain I Activation and Cytoskeletal Degradation, Improves Neurological Function, and Enhances Axonal Survival After Traumatic Spinal Cord Injury

  2000cites this paper
• Pain following spinal cord injury: pathophysiology and central mechanisms.

  2000cites this paper
• The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury.

  1999cites this paper
• The affinity of lipid-coated microbubbles to maturing spinal cord injury sites.

  1999cites this paper
• Maitotoxin Induces Calpain But Not Caspase-3 Activation and Necrotic Cell Death in Primary Septo-Hippocampal Cultures

  1999cites this paper
• Increased calpain I-mediated proteolysis, and preferential loss of dephosphorylated NF200, following traumatic spinal cord injury.

  1999cites this paper
• Calpain activity and translational expression increased in spinal cord injury.

  1999cites this paper
• Calcium influx and activation of calpain I mediate acute reactive gliosis in injured spinal cord.

  1999cites this paper
• Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical Inhibitors a

  1998cites this paper
• Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors.

  1998cites this paper
• A Review of the Pathophysiology of Cervical Spondylotic Myelopathy With Insights for Potential Novel Mechanisms Drawn From Traumatic Spinal Cord Injury

  1998cites this paper
• Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury.

  1997cites this paper
• Role of Calpain and Its Inhibitors in Tissue Degeneration and Neuroprotection in Spinal Cord Injury a

  1997cites this paper