A Review of Cardiac and Non-Cardiac Causes of Troponin Elevation and Clinical Relevance Part II: Non Cardiac Causes

S. Amiel

Published 2018 in Journal of Cardiology & Current Research

ABSTRACT

Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium mediated interaction between actin and myosin [1]. The troponin complex consists of three subunits: troponin C, troponin I, and troponin T. This complex is located on the myofibrillar thin (actin) filament of striated (skeletal and cardiac) muscle. The cardiac isoforms troponin T and I are only expressed in cardiac muscle [1].

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