Novel oral dosage regimen based on self-nanoemulsifying drug delivery systems for codelivery of phytochemicals – Curcumin and thymoquinone

Majed Alwadei,Mohsin Kazi,F. Alanazi

Published 2019 in Saudi Pharmaceutical Journal

ABSTRACT

Graphical abstract Curcumin (CUR) and Thymoquinone (THQ) were formulated using self-nanoemulsifying drug delivery systems (SNEDDS) as combined dosage form. The solubility, stability and drug release in dissolution media were significantly improved by the SNEDDS formulation compare to the raw drug powder. Schematic Diagram: Dosage form design and CUR & THQ release after oral administration of lipid-based SNEDDS formulations.

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