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Comparative efficiency of intravenous and oral iron preparations in anemic pregnant women

Аnna S. Atajanyan,Атаджанян Анна Сариковна,M. Zaynulina,Зайнулина Марина Сабировна,E. Malakhovskaya,Малаховская Елена Алексеевна

Published 2019 in Journal of obstetrics and women's diseases

ABSTRACT

Hypothesis/aims of study. The article is devoted to assessing the effectiveness of intravenous iron preparations in the treatment of anemia in pregnant women. The relevance of improving the treatment of pregnant women with iron deficiency anemia (IDA) is due to an increase in morbidity and adverse effects on the course and outcome of the gestational process, the state of the fetus and newborn. The aim of this comparative study was to assess the efficiency of intravenous and oral iron preparations in pregnant women with IDA. Study design, materials and methods. The study included 131 pregnant women. The mean age of the patients was 31.75 (19; 49) years. Results. The intravenous preparation of iron carboxymaltosate, after a single administration, has a more pronounced dynamics of hematological and ferrokinetical blood parameters compared to the oral preparation of iron (III) hydroxide polymaltosate after one month of treatment. Conclusion. As a result of clinical and laboratory research, the expediency of the use of intravenous iron (III) preparations in the 2nd and 3rd trimester of pregnancy has been substantiated. Iron carboxymaltose exhibits high clinical efficiency, quickly replenishing iron stores in the body. The absence of side effects and ease of use (single administration) allow recommending iron carboxymaltose for the treatment of IDA.

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