Antifungal peptides: Biosynthesis, production and applications

N. Mirza,Snehasri Motamarry,Preetha Bhadra,Bishwambhar Mishra

Published 2018 in Bioscience Biotechnology Research Communications

ABSTRACT

Fungal infections in animal, plants and fungal contamination of food for humans and livestock result in substantial worldwide economic losses. In the last few years, fungal infection has increased strikingly by a rise in the number of deaths of acquired immunodefi ciency syndrome (AIDS) cancer patients, transplant patients owing to fungal infections. The growth rate of fungi is very slow as compared to bacteria and very diffi cult to identify. Approximately 100 peptides have been investigated to date for their antifungal properties, which can be of great importance to overcome the human diseases. Insects secrete such compounds, which can be peptides, as a part of their immune defense reactions. Antifungal peptides are excellent models for drug discovery exhibiting unique characteristics such as high specifi city, broad spectrum, low level of resistance reaching and unique mode of action. The aim of this review is to provide information on research on these important peptides.

PUBLICATION RECORD

  • Publication year

    2018

  • Venue

    Bioscience Biotechnology Research Communications

  • Publication date

    2018-09-25

  • Fields of study

    Biology, Medicine, Chemistry, Environmental Science

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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CLAIMS

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  • No concepts are published for this paper.

REFERENCES

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