High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Chemical Research in Toxicology

• Publication date

  2018-04-24

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1021/acs.chemrestox.8b00008PMID 29688711PMCID PMC7075635
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fatty Acid

  2020cited by this paper
• Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions.

  2017cited by this paper
• Metabolism disrupting chemicals and metabolic disorders.

  2017cited by this paper
• PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

  2017cited by this paper
• Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism

  2017cited by this paper
• Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis.

  2017cited by this paper
• The Role of Oxysterols in Human Cancer.

  2017cited by this paper
• Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome.

  2016cited by this paper
• Role of Cytochrome P450 Hydroxylase in the Decreased Accumulation of Vitamin E in Muscle from Turkeys Compared to that from Chickens.

  2016cited by this paper
• Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

  2016cited by this paper
• Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome.

  2016cited by this paper
• Probiotics in prevention and treatment of obesity: a critical view

  2016cited by this paper
• Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism.

  2016cited by this paper
• Improving Medication Dosing in the Obese Patient

  2016cited by this paper
• Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma

  2016cited by this paper
• Diet dominates host genotype in shaping the murine gut microbiota.

  2015cited by this paper
• Eicosanoid storm in infection and inflammation

  2015cited by this paper
• Special Section on DrugMetabolism and the Microbiome—Commentary Drug Metabolism by the Host and Gut Microbiota: A Partnership or Rivalry?

  2015cited by this paper
• Review, evaluation, and discussion of the challenges of missing value imputation for mass spectrometry-based label-free global proteomics.

  2015cited by this paper
• Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes.

  2014cited by this paper
• Bile acids, obesity, and the metabolic syndrome.

  2014cited by this paper
• Genetics, Epigenetics, and Regulation of Drug‐Metabolizing Cytochrome P450 Enzymes

  2014cited by this paper
• Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

  2014cited by this paper
• Acetaminophen‐induced liver injury in obesity and nonalcoholic fatty liver disease

  2014cited by this paper
• The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts

  2014cited by this paper
• Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse.

  2014cited by this paper
• Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.

  2013cited by this paper
• Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

  2013cited by this paper
• Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice.

  2013cited by this paper
• Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.

  2013cited by this paper
• A comparative analysis of computational approaches to relative protein quantification using peptide peak intensities in label‐free LC‐MS proteomics experiments

  2013cited by this paper
• AhR activation underlies the CYP1A autoinduction by A-998679 in rats

  2012cited by this paper
• DanteR: an extensible R-based tool for quantitative analysis of -omics data

  2012cited by this paper
• Differential Development of Glucose Intolerance and Pancreatic Islet Adaptation in Multiple Diet Induced Obesity Models

  2012cited by this paper
• Cytochromes P450 catalyze the reduction of α,β-unsaturated aldehydes.

  2011cited by this paper
• Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: mechanisms and pathophysiological role.

  2011cited by this paper
• Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress?

  2011cited by this paper
• The metabolic syndrome, smoking, inflammatory markers and obesity.

  2011cited by this paper
• Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus

  2011cited by this paper
• A statistical method for assessing peptide identification confidence in accurate mass and time tag proteomics.

  2011cited by this paper
• Tissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.

  2011cited by this paper
• Improved quality control processing of peptide-centric LC-MS proteomics data

  2011cited by this paper
• Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P 450 mRNAs in Mice

  2011cited by this paper
• Effect of Obesity on the Pharmacokinetics of Drugs in Humans

  2010cited by this paper
• Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1

  2010cited by this paper
• Combined Statistical Analyses of Peptide Intensities and Peptide Occurrences Improves Identification of Significant Peptides from MS-Based Proteomics Data

  2010cited by this paper
• Efficient Hypoxic Activation of the Anticancer Agent AQ 4 N by CYP 2 S 1 and CYP 2 W 1

  2010cited by this paper
• Expression, Function and Regulation of Mouse Cytochrome P450 Enzymes: Comparison With Human Cytochrome P450 Enzymes

  2009cited by this paper
• Role of bile acids and bile acid receptors in metabolic regulation.

  2009cited by this paper
• Fatty Acid Hydroperoxides Support Cytochrome P450 2S1-Mediated Bioactivation of Benzo[a]pyrene-7,8-dihydrodiol

  2009cited by this paper
• A suite of activity-based probes for human cytochrome P450 enzymes.

  2009cited by this paper
• Expression, function and regulation of mouse cytochrome P450 enzymes: comparison with human P450 enzymes.

  2009cited by this paper
• DAnTE: a statistical tool for quantitative analysis of -omics data

  2008cited by this paper
• Spectral probabilities and generating functions of tandem mass spectra: a strike against decoy databases.

  2008cited by this paper
• CYP 1 A Induction and Human Risk Assessment : An Evolving Tale of in Vitro and in Vivo Studies

  2007cited by this paper
• Chemical proteomic probes for profiling cytochrome p450 activities and drug interactions in vivo.

  2007cited by this paper
• CYP1A Induction and Human Risk Assessment: An Evolving Tale of in Vitro and in Vivo Studies

  2007cited by this paper
• A prospective study of acute drug‐induced liver injury in patients suffering from non‐alcoholic fatty liver disease

  2007cited by this paper
• Advances in proteomics data analysis and display using an accurate mass and time tag approach.

  2006cited by this paper
• Normalization Regarding Non-Random Missing Values in High-Throughput Mass Spectrometry Data

  2005cited by this paper
• Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

  2004cited by this paper
• The farnesoid X receptor

  2004cited by this paper
• Characterization of Mainstream Cigarette Smoke-Induced Biomarker Responses in ICR and C57Bl/6 Mice

  2004cited by this paper
• Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy.

  2003cited by this paper
• Clinical importance of the cytochromes P450.

  2002cited by this paper
• Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.

  2000cited by this paper
• Effects of obesity on pharmacokinetics implications for drug therapy.

  2000cited by this paper
• Effects of obesity on the cytochrome P450 enzyme system.

  1999cited by this paper
• Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

  1999cited by this paper
• Role of murine cytochrome P-450 2F2 in metabolic activation of naphthalene and metabolism of other xenobiotics.

  1999cited by this paper
• Cytochrome P450

  1993cited by this paper
• Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.

  1992cited by this paper
• Experiments

  1986cited by this paper

• The stereoselective pharmacokinetics of bupivacaine after racemate, and the effects of high-fat diet and sex in Sprague-Dawley rats.

  2025cites this paper
• Impact of aldosterone deficiency on the development of diuretic resistance in mice

  2025cites this paper
• The Effect of Clinical Factors on the Reversion of Cg05575921 Methylation in Smoking Cessation

  2025cites this paper
• Characteristics Analysis and Intestinal Effects of Probiotic‐Derived Nano‐Selenium by Lactobacillus bulgaricus CICC 20247

  2025cites this paper
• Proteomic characterization of Mycobacterium tuberculosis subjected to carbon starvation

  2024cites this paper
• Association between dietary exposure to chemical contaminants and risk of dementia in older persons.

  2024cites this paper
• The Effect of Maternal High-Fat or High-Carbohydrate Diet during Pregnancy and Lactation on Cytochrome P450 2D (CYP2D) in the Liver and Brain of Rat Offspring

  2024cites this paper
• Profiling protein targets of cellular toxicant exposure.

  2023cites this paper
• Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study

  2023cites this paper
• Activity‐Based Protein Profiling of Oxidases and Reductases

  2023cites this paper
• Association of environmental tobacco smoke exposure with chronic constipation: a nationwide survey (NHANES 2005–2010)

  2023cites this paper
• Effects of Crocodile Oil (Crocodylus siamensis) on Liver Enzymes: Cytochrome P450 and Glutathione S-Transferase Activities in High-fat DietFed Rats

  2022cites this paper
• Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?

  2022cites this paper
• Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure.

  2022cites this paper
• Effect of nutritional status on acetaminophen pharmacokinetic profile.

  2022cites this paper
• Obesity-related genomic instability and altered xenobiotic metabolism: possible consequences for cancer risk and chemotherapy

  2022cites this paper
• Liver proteome profiling in dairy cows during the transition from gestation to lactation: Effects of supplementation with essential fatty acids and conjugated linoleic acids as explored by PLS-DA.

  2021influential citation
• Body mass index as a determinant of clozapine plasma concentrations: A pharmacokinetic-based hypothesis

  2021cites this paper
• Mechanistic Targets and Nutritionally Relevant Intervention Strategies to Break Obesity–Breast Cancer Links

  2021cites this paper
• Cytochrome P450 2F2 (CYP2F2) negatively regulates browning in 3T3-L1 white adipocytes.

  2021cites this paper
• Renal NKCC2 Is Dual Regulated by the Synergy of 20-HETE and High-Fat Diet in CYP4F2 Transgenic Mice

  2021cites this paper
• Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice

  2021cites this paper
• Multiomic profiling of the liver across diets and age in a diverse mouse population.

  2021cites this paper
• Activity‐Based Protein Profiling (ABPP) of Oxidoreductases

  2020cites this paper
• Cytochrome P450 expression-associated multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD) in HepG2 cells

  2020cites this paper
• The Importance and Future of Biochemical Engineering.

  2020cites this paper
• The Molecular Landscape of the Aging Mouse Liver

  2020cites this paper
• Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models

  2019cites this paper
• Polycyclic aromatic hydrocarbons in the bottom sediments of Elburgon River—Kenya: precursors for cancer

  2019cites this paper
• Chemoproteomic Analyses by Activity‐Based Protein Profiling

  2019cites this paper
• The protective effect of epigallocatechin-3-gallate on testicular oxidative stress in lead-induced toxicity mediated by Cyp19 gene / estradiol level.

  2019cites this paper
• Biochemical and molecular evidence on the role of vaspin in early detection of the insulin resistance in a rat model of high-fat diet and use of diazinon.

  2019cites this paper
• Drug-induced liver injury in obesity and nonalcoholic fatty liver disease.

  2019cites this paper
• Nutritional conditioning : The effect of a short-term high fat diet on hepatic drug metabolism

  2019cites this paper
• Expression Patterns of Xenobiotic-Metabolizing Enzymes in Tumor and Adjacent Normal Mucosa Tissues among Patients with Colorectal Cancer: The ColoCare Study

  2019cites this paper