SCIENCE@home

Oral mucositis in children with cancer and their relationship with limitation of activities

M. Palomo-Colli,Diana Carolina Soltero-Becerril,L. Villegas,C. Cicero-Oneto,J. F. Gaytán-Morales,I. Castorena-Villa,Mónica Mier-Cabrera

Published 2019 in Gaceta Mexicana de Oncología

ABSTRACT

Introduction: Oral mucositis (OM) is a common chemo and radiotherapy adverse effect in oncological pediatric patients, oral complications may be observed during chemotherapy and are important side effects that may directly affect the anticancer treatment. Methods: We included 420 children and monitored them for 2 weeks after the initiation of chemotherapy between June 2012 and June 2016. Subjects were asked to use a daily diary to complete the related questions of the OM Daily Questionnaire from the start of chemotherapy to day 14. Results: Overall, 73% (n = 307) of paediatric patients developed OM. Most cases were Grade 2 and 3. Of these, 12% (n = 32) were Grade 1, and 49% (n = 205) Grade 2. The mean time to onset of OM was 4.5 (standard deviation [SD]: 2.5; range: 2-9; 95% confidence interval [CI]: 3.8-5.3) days after the start of chemotherapy, with a mean duration of 6.5 (SD: 4; range: 2-13; 95% CI: 5.2-9.4) days and with the peak at day 7.1 (SD: 2.8; range: 4-11; 95% CI: 6.8-8.4). Conclusions: OM is associated with negative effects on clinical outcomes.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-14 of 14 references · Page 1 of 1

CITED BY