Chemical characterization and antifungal activity of Origanum vulgare, Thymus vulgaris essential oils and carvacrol against Malassezia furfur

Abstract The composition of the essential oils (EOs) of O. vulgare L. EO and T. vulgaris EO, were analyzed by GC and GC–MS. Antifungal activities of the EOs and its main component, carvacrol, were evaluated against 27 clinical isolates of Malassezia furfur. Minimum inhibitory concentrations (MICs) were measured according to the broth microdilution protocols by Clinical and Laboratory Standards Institute (CLSI) modified for Malassezia spp. EOs and carvacrol showed low MIC values ranged 450–900 μg/ml against M. furfur. No differences in EOs antifungal activity were observed in sensitive to resistant fluconazole isolates. The antifungal activity obtained showed O. vulgare EO, T. vulgaris EO and carvacrol, their compound, as potential antimicrobial agents against M. furfur, yeast associated with human mycoses.

• Publication year

  2019

• Venue

  Natural Product Research

• Publication date

  2019-11-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1080/14786419.2018.1468325PMID 29726703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biofilm, adherence, and hydrophobicity as virulence factors in Malassezia furfur

  2018cited by this paper
• Chemical composition, antimicromicrobial activity and insecticidal activity against the lesser mealworm Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) of Origanum vulgare L. ssp. hirtum (Link) and Artemisia dracunculus L. essential oils.

  2018cited by this paper
• Antifungal Activity of Thapsia villosa Essential Oil against Candida, Cryptococcus, Malassezia, Aspergillus and Dermatophyte Species

  2017influential reference
• Assessment of Antioxidant and Antibacterial Properties on Meat Homogenates of Essential Oils Obtained from Four Thymus Species Achieved from Organic Growth

  2017cited by this paper
• Investigation of the antifungal activity of carvacrol against strains of Cryptococcus neoformans

  2016cited by this paper
• Efficacy of medicinal essential oils against pathogenic Malassezia sp. isolates.

  2016influential reference
• Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh †

  2015cited by this paper
• In vitro toxicological evaluation of essential oils and their main compounds used in active food packaging: A review.

  2015cited by this paper
• Antifungal activity and mode of action of carvacrol against Candida albicans strains

  2013cited by this paper
• Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil.

  2013cited by this paper
• Essential Oils in Food Preservation: Mode of Action, Synergies, and Interactions with Food Matrix Components

  2012cited by this paper
• Malassezia Fungi Are Specialized to Live on Skin and Associated with Dandruff, Eczema, and Other Skin Diseases

  2012cited by this paper
• Antimicrobial activity of carvacrol: current progress and future prospectives.

  2012cited by this paper
• Prevalence of Malassezia species in pityriasis versicolor lesions in northeast Argentina.

  2010cited by this paper
• Reference method for broth dilution antifungal susceptibility testing of yeasts : Approved standard

  2008cited by this paper
• Identification of Essential Oil Components By Gas Chromatography/Mass Spectrometry

  2007cited by this paper
• Update on the genus Malassezia.

  2007cited by this paper
• Antifungal effect of various essential oils against Candidaalbicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris

  2004cited by this paper
• The Phenolic Hydroxyl Group of Carvacrol Is Essential for Action against the Food-Borne Pathogen Bacillus cereus

  2002cited by this paper
• A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol

  2001cited by this paper
• In Vitro Activities of Ketoconazole, Econazole, Miconazole, and Melaleuca alternifolia (Tea Tree) Oil against Malassezia Species

  2000cited by this paper
• Antifungal activity of the essential oil of Melaleuca alternifolia (tea tree oil) against pathogenic fungi in vitro.

  1996influential reference
• Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicon and Carbowax 20M phases

  1990cited by this paper

• Carvacrol Reduces Virulence Traits in Meyerozyma guilliermondii and Candida dubliniensis and Enhances Galleria mellonella Survival During Candidozyma auris Infection

  2026cites this paper
• Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

  2026cites this paper
• A comprehensive review on herbal approaches for treatment of urinary tract infections: Scope and challenges

  2025cites this paper
• Theranostic nanomaterials for scalp and hair fungal infections: advancing diagnosis and treatment amidst challenges

  2025cites this paper
• Aromatherapy in combating human pathogens and diseases: Impact and prospects

  2025cites this paper
• Origanum Essential Oil and Antifungal Activity: A Systematic Review

  2025cites this paper
• Nigrospora sp. in post-harvest papayas: efficacy of essential oils in antifungal inhibition

  2025cites this paper
• Carvacrol and Thymol, a Synergistic Antimicrobial Activity Against Bacterial and Candida Species

  2025cites this paper
• Synergistic effect of essential oils and chlorhexidine against planktonic and biofilm-forming cells of Malassezia pachydermatis

  2024cites this paper
• Antimicrobial Properties of the Essential Oils of New Varieties of Origanum Vulgare L.

  2024cites this paper
• Carvacrol as a food additive: Toxicological aspects and the role of nanotechnology in enhancing its antimicrobial and antioxidant properties.

  2024cites this paper
• A greener side of health care: Revisiting phytomedicine against the human fungal pathogen Malassezia.

  2024cites this paper
• Antiviral Efficacy of Coridothymus capitatus Essential Oil Against HSV-1 and HSV-2

  2024cites this paper
• Carvacrol alters the membrane phospholipid in erythromycin-resistant Streptococcus pyogenes

  2024cites this paper
• Spray Coating of Wood with Nanoparticles from Lignin and Polylactic Glycolic Acid Loaded with Thyme Essential Oils

  2024cites this paper
• Possible plant-based solutions for skin yeast infections

  2024cites this paper
• ANTIMICROBIAL PROPERTIES OF NEW VARIETIES OF ORIGANUM VULGARE ESSENTIAL OILS

  2023cites this paper
• Natural antimicrobial systems protected by complex polyhydroxyalkanoate matrices for food biopackaging applications - A review.

  2023cites this paper
• In vitro toxicity of combination of amitraz and carvacrol on Demodex canis

  2023cites this paper
• Lignin Nanoparticles with Entrapped Thymus spp. Essential Oils for the Control of Wood-Rot Fungi

  2023cites this paper
• Essential oils of Origanum Species from Turkey: Repellent Activity Against Stored Product Insect Pests

  2023cites this paper
• Essential Oil of Origanum vulgare var. aureum L. from Western Romania: Chemical Analysis, In Vitro and In Silico Screening of Its Antioxidant Activity

  2023cites this paper
• Green biocides for the conservation of hypogeal mural paintings raised from Western and Eastern traditions: Evaluation of interference on pigments and substrata and multifactor parameters affecting their activity

  2023cites this paper
• Modulatory effect of Origanum vulgare essential oil and carvacrol on Malassezia spp. virulence factors.

  2023cites this paper
• Bactericidal Activity of Carvacrol against Streptococcus pyogenes Involves Alteration of Membrane Fluidity and Integrity through Interaction with Membrane Phospholipids

  2022cites this paper
• Nanoparticles—Attractive Carriers of Antimicrobial Essential Oils

  2022cites this paper
• Synthesis and evaluation of novel 1-(((6-substitutedbenzo[d]thiazol-2-yl)amino)(heteroaryl)methyl)naphthalen-2-ol as pesticidal agents

  2022cites this paper
• Essential oils from different Citrus species and evaluation of their in vitro antibacterial, antiacetylcholinesterase, anti-inflammatory and antifungal activities

  2022cites this paper
• Correlation between the chemical composition and the antimicrobial properties of seven samples of essential oils of endemic Thymes in Morocco against multi-resistant bacteria and pathogenic fungi

  2022cites this paper
• Recent progress in eco-synthesis of essential oil-based nanoparticles and their possible mechanisms

  2022cites this paper
• Nanotechnology as a tool to improve the biological activity of carvacrol: A review

  2022cites this paper
• Determination of essential oil ratios and components of Origanum species grown in Çukurova conditions

  2022cites this paper
• Herbal Therapy for the Treatment of Seborrhea Dermatitis

  2022cites this paper
• "In vivo" and "in vitro" antimicrobial activity of Origanum vulgare essential oil and its two phenolic compounds on clinical isolates of Candida spp.

  2022cites this paper
• Comparative toxicological evaluation of carvacrol, acetylcarvacrol anda fipronil-based pesticide in human blood cells

  2022cites this paper
• Antifungal Carvacrol Loaded Chitosan Nanoparticles

  2021cites this paper
• Essential oils as natural antimicrobial agents in postharvest treatments of fruits and vegetables: a review

  2021cites this paper
• Larvicidal, adulticidal and repellent activities against Aedes aegypti L. of two commonly used spices, Origanum vulgare L. and Thymus vulgaris L.

  2021cites this paper
• Essential Oils and Their Application in Food Safety

  2021cites this paper
• Formulation of Anti-Fungal Cream to Treat Onychomycosis

  2021cites this paper
• Medicinal Plants Used by Traditional Healers in Algeria: A Multiregional Ethnobotanical Study

  2021cites this paper
• Formulation and antimicrobial activity evaluation of a 0.2% chlorhexidine canine mouthwash with essential oils

  2021cites this paper
• Essential oils and their components in combating fungal pathogens of animal and human skin.

  2021cites this paper
• Phenols from Origanum dictamnus L. and Thymus vulgaris L. and their activity against Malassezia globosa carbonic anhydrase

  2021cites this paper
• Carvacrol exhibits rapid bactericidal activity against Streptococcus pyogenes through cell membrane damage

  2021cites this paper
• Antifungal Activity of the Essential Oils of Osteophloeum platyspermum (Myristicaceae) against Malassezia spp. and Candida albicans Influenced by Seasonality and Climatic Factors

  2021cites this paper
• Features of the Bacillus thuringiensis 888 strain’s influence on the content of essential oil, antioxidants and flavonoids in Origanum vulgare L.

  2021cites this paper
• Essential Oils of Lamiaceae Family Plants as Antifungals

  2020cites this paper
• The phenolic contents, antioxidant and anticholinesterase activity of section Amaracus (Gled.) Vogel and Anatolicon Ietsw. of Origanum L. species

  2020cites this paper
• Essential Oils and Mono/bi/tri-Metallic Nanocomposites as Alternative Sources of Antimicrobial Agents to Combat Multidrug-Resistant Pathogenic Microorganisms: An Overview

  2020cites this paper
• Chemical Compositions and Anti-Skin-Ageing Activities of Origanum vulgare L. Essential Oil from Tropical and Mediterranean Region

  2020cites this paper
• A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil

  2020cites this paper
• Conventional therapy and new antifungal drugs against Malassezia infections.

  2020cites this paper
• Ursolic Acid-Based Derivatives as Potential Anti-Cancer Agents: An Update

  2020cites this paper
• Phytochemical constituents, biological activities, and health‐promoting effects of the genus Origanum

  2020cites this paper
• Chemical composition and insecticidal potential of different Origanum spp. (Lamiaceae) essential oils against four stored product pests

  2020cites this paper
• Eugenia pyriformis Cambess: a species of the Myrtaceae family with bioactive essential oil

  2019cites this paper
• Synergistic inactivation of multidrug-resistant Pseudomonas aeruginosa by essential oil and blue light

  2019cites this paper
• An Open Study to Evaluate Effectiveness and Tolerability of a Nail Oil Composed of Vitamin E and Essential Oils in Mild to Moderate Distal Subungual Onychomycosis

  2019cites this paper
• Antifungal activity of different essential oils against Malassezia pathogenic species.

  2019cites this paper
• Essential Oils as Antimicrobial Agents—Myth or Real Alternative?

  2019cites this paper