A model for extra-axonal diffusion spectra with frequency-dependent restriction

In the brain, there is growing interest in using the temporal diffusion spectrum to characterize axonal geometry in white matter because of the potential to be more sensitive to small pores compared to conventional time‐dependent diffusion. However, analytical expressions for the diffusion spectrum of particles have only been derived for simple, restricting geometries such as cylinders, which are often used as a model for intra‐axonal diffusion. The extra‐axonal space is more complex, but the diffusion spectrum has largely not been modeled. We propose a model for the extra‐axonal space, which can be used for interpretation of experimental data.

• Publication year

  2014

• Venue

  Magnetic Resonance in Medicine

• Publication date

  2014-07-15

• Fields of study

  Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1002/mrm.25363PMID 25046481PMCID 4682484
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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