Cnidarian Toxins Acting on Voltage-Gated Ion Channels

Shanta M. Messerli,R. Greenberg

Published 2006 in Marine Drugs

ABSTRACT

Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.

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