Protective effect and mechanism of lycopene on endothelial progenitor cells (EPCs) from type 2 diabetes mellitus rats.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

• Publication date

  2017-08-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.biopha.2017.05.018PMID 28531804
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelial progenitor cells dysfunction and impaired tissue reparation: The missed link in diabetes mellitus development.

  2017cited by this paper
• Inhibition of autophagy increased AGE/ROS-mediated apoptosis in mesangial cells

  2016cited by this paper
• Advanced glycation endproducts induce apoptosis of endothelial progenitor cells by activating receptor RAGE and NADPH oxidase/JNK signaling axis.

  2016cited by this paper
• AGEs trigger autophagy in diabetic skin tissues and fibroblasts.

  2016cited by this paper
• Autophagy mechanisms in sputum and peripheral blood cells of patients with severe asthma: a new therapeutic target

  2016cited by this paper
• Spatane diterpinoid from the brown algae, Stoechospermum marginatum induces apoptosis via ROS induced mitochondrial mediated caspase dependent pathway in murine B16F10 melanoma cells

  2016cited by this paper
• Atorvastatin protects endothelial colony-forming cells against H2O2-induced oxidative damage by regulating the expression of annexin A2

  2015cited by this paper
• Enhancement of oxaliplatin-induced cell apoptosis and tumor suppression by 3-methyladenine in colon cancer.

  2015cited by this paper
• Sulforaphane inhibits thyroid cancer cell growth and invasiveness through the reactive oxygen species-dependent pathway

  2015cited by this paper
• Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress‐Induced Autophagy in Endothelial Progenitor Cells

  2015cited by this paper
• Advanced Glycation End Products (AGE) Potently Induce Autophagy through Activation of RAF Protein Kinase and Nuclear Factor κB (NF-κB)*

  2015cited by this paper
• Coenzyme Q10 Attenuates High Glucose-Induced Endothelial Progenitor Cell Dysfunction through AMP-Activated Protein Kinase Pathways

  2015cited by this paper
• Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus

  2015cited by this paper
• The protective effect of Smilax glabra extract on advanced glycation end products-induced endothelial dysfunction in HUVECs via RAGE-ERK1/2-NF-κB pathway.

  2014cited by this paper
• Advanced glycation endproducts trigger autophagy in cadiomyocyte Via RAGE/PI3K/AKT/mTOR pathway

  2014cited by this paper
• Circulating mouse Flk1+/c-Kit+/CD45- cells function as endothelial progenitors cells (EPCs) and stimulate the growth of human tumor xenografts

  2014cited by this paper
• Lycopene Treatment of Prostate Cancer Cell Lines Inhibits Adhesion and Migration Properties of the Cells

  2014cited by this paper
• Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines

  2014cited by this paper
• Effects of lycopene on number and function of human peripheral blood endothelial progenitor cells cultivated with high glucose

  2014cited by this paper
• Synthesis and screening of 3-MA derivatives for autophagy inhibitors

  2013cited by this paper
• Impaired cross-activation of β3 integrin and VEGFR-2 on endothelial progenitor cells with aging decreases angiogenesis in response to hypoxia.

  2013cited by this paper
• Lycopene metabolism and its biological significance.

  2012cited by this paper
• Type 2 diabetes mellitus impairs the maturation of endothelial progenitor cells and increases the number of circulating endothelial cells in peripheral blood

  2012cited by this paper
• Advanced glycation end products impair the migration, adhesion and secretion potentials of late endothelial progenitor cells

  2012cited by this paper
• Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells.

  2011cited by this paper
• Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression.

  2011cited by this paper
• Nitric oxide: a key factor behind the dysfunctionality of endothelial progenitor cells in diabetes mellitus type-2.

  2011cited by this paper
• Serum Lycopene Concentration and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial

  2011cited by this paper
• Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells.

  2010cited by this paper
• TGF-β1 Protects against Mesangial Cell Apoptosis via Induction of Autophagy*

  2010cited by this paper
• Amelioration of streptozotocin‐induced diabetes mellitus, oxidative stress and dyslipidemia in rats by tomato extract lycopene

  2009cited by this paper
• Advanced glycation end products impair function of late endothelial progenitor cells through effects on protein kinase Akt and cyclooxygenase-2.

  2009cited by this paper
• Advanced glycation endproducts alter functions and promote apoptosis in endothelial progenitor cells through receptor for advanced glycation endproducts mediate overpression of cell oxidant stress

  2009cited by this paper
• Daily intake of thiamine correlates with the circulating level of endothelial progenitor cells and the endothelial function in patients with type II diabetes.

  2008cited by this paper
• Tomatoes versus lycopene in oxidative stress and carcinogenesis: conclusions from clinical trials

  2007cited by this paper
• Physiological dose of lycopene suppressed oxidative stress and enhanced serum levels of immunoglobulin M in patients with Type 2 diabetes mellitus: A possible role in the prevention of long-term complications

  2007cited by this paper
• The opposite associations of lycopene and body fat mass with humoral immunity in type 2 diabetes mellitus: a possible role in atherogenesis.

  2007cited by this paper
• Mortality within the first 10 years of the disease in type 2 diabetic patients.

  2006cited by this paper
• Glycated Proteins Stimulate Reactive Oxygen Species Production in Cardiac Myocytes: Involvement of Nox2 (gp91phox)-Containing NADPH Oxidase

  2006cited by this paper
• Lycopene and prostate cancer

  2002cited by this paper
• Global and societal implications of the diabetes epidemic

  2001cited by this paper
• Heterogeneity of endothelial cells. Specific markers.

  1997cited by this paper

• Lycopene attenuates trimethylamine-N-oxide-induced senescence in endothelial progenitor cells via the AMPK/SIRT1 pathway

  2025cites this paper
• Mechanistic insights on lycopene usage against diabetes and associated complications

  2025cites this paper
• Natural autophagy modulators in non-communicable diseases: from autophagy mechanisms to therapeutic potential

  2024cites this paper
• Lycopene inhibits pyroptosis of endothelial progenitor cells induced by ox-LDL through the AMPK/mTOR/NLRP3 pathway

  2024cites this paper
• Enhancement of Biochemical and Genomic Pathways through Lycopene-Loaded Nano-Liposomes: Alleviating Insulin Resistance, Hepatic Steatosis, and Autophagy in Obese Rats with Non-Alcoholic Fatty Liver Disease: Involvement of SMO, GLI-1, and PTCH-1 Genes.

  2023cites this paper
• Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

  2023cites this paper
• Macrovascular and microvascular type 2 diabetes complications are interrelated in a mouse model.

  2023cites this paper
• Bone Marrow as a Therapeutic Target for Type 2 Diabetes Complications.

  2023cites this paper
• Targeting the redox system for cardiovascular regeneration in aging

  2023cites this paper
• The sources, properties, extraction, biosynthesis, pharmacology, and application of lycopene.

  2023cites this paper
• Potentially active compounds that improve PAD through angiogenesis: A review.

  2023cites this paper
• Nutraceuticals as Modulators of Autophagy: Relevance in Parkinson’s Disease

  2022cites this paper
• Therapeutic effect of lycopene in lipopolysaccharide nephrotoxicity through alleviation of mitochondrial dysfunction, inflammation, and oxidative stress

  2022cites this paper
• Lycopene: A Potent Antioxidant for the Amelioration of Type II Diabetes Mellitus

  2022cites this paper
• Atypical Presentations

  2022cites this paper
• Antioxidant and Age-Related Diseases

  2021cites this paper
• Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment

  2021cites this paper
• Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene.

  2021cites this paper
• Systems analysis of gut microbiome influence on metabolic disease in HIV and high-risk populations

  2021cites this paper
• ox-LDL-Induced Endothelial Progenitor Cell Oxidative Stress via p38/Keap1/Nrf2 Pathway

  2021cites this paper
• Lycopene mitigates arsenic-induced nephrotoxicity with activation of the Nrf2 pathway in mice

  2021cites this paper
• Medicinal Plants, Bioactive Compounds, and Dietary Therapies for Treating Type 1 and Type 2 Diabetes Mellitus

  2021cites this paper
• Lycopene prevents oxygen-glucose deprivation-induced autophagic death in SH-SY5Y cells via inhibition of the oxidative stress-activated AMPK/mTOR pathway.

  2021cites this paper
• Advanced Glycation End Products Impair Cardiac Atrial Appendage Stem Cells Properties

  2021cites this paper
• The therapeutic effects of lycopene on mitochondrial function in human diseases

  2021cites this paper
• Lycopene: From tomato to its nutraceutical use and its association with nanotechnology

  2021cites this paper
• MicroRNA-126 and VEGF enhance the function of endothelial progenitor cells in acute myocardial infarction

  2021cites this paper
• Exendin-4 reverses high glucose-induced endothelial progenitor cell dysfunction via SDF-1β/CXCR7–AMPK/p38-MAPK/IL-6 axis

  2020cites this paper
• Influence of hot and cold break tomato powders on survival of probiotic L. paracasei subsp. paracasei F19, texture profile and antioxidative activity in set-type yoghurts

  2020cites this paper
• Lycopene in protection against obesity and diabetes: A mechanistic review.

  2020cites this paper
• The Impact of Advanced Glycation End-Products (AGEs) on Proliferation and Apoptosis of Primary Stem Cells: A Systematic Review

  2020cites this paper
• Lycopene Improves the Metformin Effects on Glycemic Control and Decreases Biomarkers of Glycoxidative Stress in Diabetic Rats

  2020cites this paper
• Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders

  2020cites this paper
• The Remedial Potential of Lycopene in Pancreatitis through Regulation of Autophagy

  2020cites this paper
• DMSO_A_265944 3117..3135

  2020cites this paper
• Nutraceuticals and their Nanotechnology-Based Therapeutic Applications in Different Diseases

  2020cites this paper
• Effect of mitochondrial quality control on the lycopene antagonizing DEHP-induced mitophagy in spermatogenic cells.

  2020cites this paper
• The Impact of Tomato Juice on Reducing Blood Sugar Levels at Diabetes Mellitus Patients

  2019cites this paper
• The Impact of Natural Antioxidants on the Regenerative Potential of Vascular Cells

  2019cites this paper
• Effects and Underlying Mechanisms of Bioactive Compounds on Type 2 Diabetes Mellitus and Alzheimer's Disease

  2019cites this paper
• Lycopene and Vascular Health

  2018cites this paper
• Role of Autophagy in Endothelial Damage and Blood–Brain Barrier Disruption in Ischemic Stroke

  2018cites this paper
• Use of Nutraceuticals in Angiogenesis-Dependent Disorders

  2018influential citation
• Natural Products Modulating Autophagy Pathway Against the Pathogenesis of Diabetes Mellitus.

  2018cites this paper
• MiR-31 regulates the function of diabetic endothelial progenitor cells by targeting Satb2

  2018cites this paper
• Expression of MicroRNA-448 and SIRT1 and Prognosis of Obese Type 2 Diabetic Mellitus Patients After Laparoscopic Bariatric Surgery

  2018cites this paper