A hydrogenosome with pyruvate formate‐lyase: anaerobic chytrid fungi use an alternative route for pyruvate catabolism

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Molecular Microbiology

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1046/j.1365-2958.1999.01434.xPMID 10361311
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1998influential reference
• The hydrogen hypothesis for the first eukaryote

  1998cited by this paper
• The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF‐I) protein

  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Overview of the yeast genome.

  1997cited by this paper
• Erratum: Overview of the yeast genome

  1997cited by this paper
• The complete genome sequence of Escherichia coli K-12.

  1997cited by this paper
• Evolution of the hydrogenosome.

  1997cited by this paper
• Further studies on the organization of the hydrogenosome in Tritrichomonas foetus.

  1996cited by this paper
• Morphogenesis of the hydrogenosome: an ultrastructural study.

  1996cited by this paper
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  1996influential reference
• The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins

  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.

  1995cited by this paper
• Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system.

  1995cited by this paper
• Multiple origins of anaerobic ciliates with hydrogenosomes within the radiation of aerobic ciliates

  1995cited by this paper
• The Conserved Noncatalytic 40-Residue Sequence in Cellulases and Hemicellulases from Anaerobic Fungi Functions as a Protein Docking Domain (*)

  1995cited by this paper
• Horizontal gene transfer: evidence and possible consequences.

  1994cited by this paper
• Anaerobic fungi in herbivorous animals

  1994cited by this paper
• Horizontal Gene Flow: Evidence and Possible Consequences

  1994cited by this paper
• Metabolic energy generation in hydrogenosomes of the anaerobic fungus Neocallimastix: evidence for a functional relationship with mitochondria

  1994influential reference
• Isolation and characterization of cDNA sequences controlled by inorganic phosphate in Chlamydomonas reinhardtii

  1993cited by this paper
• Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.

  1993cited by this paper
• Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes

  1993cited by this paper
• The hydrogenosome.

  1993cited by this paper
• The hydrogenosomal enzyme hydrogenase from the anaerobic fungus Neocallimastix sp. L2 is recognized by antibodies, directed against the C-terminal microbody protein targeting signal SKL.

  1993influential reference
• Review Article: The hydrogenosome

  1993cited by this paper
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  1992cited by this paper
• The early evolution of eukaryotes: a geological perspective.

  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
• Characterization of an anaerobic fungus from llama faeces.

  1992cited by this paper
• Glucose metabolic pathways in the anaerobic rumen fungus Neocallimastix frontalis EB188.

  1991cited by this paper
• Comparison of growth characteristics of anaerobic fungi isolated from ruminant and non-ruminant herbivores during cultivation in a defined medium.

  1991influential reference
• Phylogeny of anaerobic rumen Chytridiomycetes inferred from small subunit ribosomal RNA sequence comparisons

  1991cited by this paper
• A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of Escherichia coli.

  1990cited by this paper
• A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of

  1990cited by this paper
• Influence of hydrogen-consuming bacteria on cellulose degradation by anaerobic fungi

  1990influential reference
• Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif.

  1989cited by this paper
• Domain structure of mitochondrial and chloroplast targeting peptides.

  1989cited by this paper
• Catalytic-site mapping of pyruvate formate lyase

  1988cited by this paper
• Catalytic-site mapping of pyruvate formate lyase. Hypophosphite reaction on the acetyl-enzyme intermediate affords carbon-phosphorus bond synthesis (1-hydroxyethylphosphonate).

  1988cited by this paper
• Primary structures of Escherichia coli pyruvate formate-lyase and pyruvate-formate-lyase-activating enzyme deduced from the DNA nucleotide sequences.

  1988cited by this paper
• Hydrogenosomes in the rumen fungus Neocallimastix patriciarum.

  1986influential reference
• Anaerobic pyruvate metabolism of Tritrichomonas foetus and Trichomonas vaginalis hydrogenosomes.

  1986cited by this paper
• A comprehensive set of sequence analysis programs for the VAX

  1984cited by this paper
• Pyruvate formate-lyase (inactive form) and pyruvate formate-lyase activating enzyme of Escherichia coli: isolation and structural properties.

  1984cited by this paper
• Respiration of the rumen ciliate Dasytricha ruminantium Schuberg.

  1982cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• A Biochemical Phylogeny of the Protists

  1979cited by this paper
• 12 – A Biochemical Phylogeny

  1978cited by this paper
• Duplication of Regulatory Genes and Receptors

  1970cited by this paper
• Evolution by Gene Duplication

  1970cited by this paper
• The hydrogenosome

  year unknowninfluential reference

• Parallel functional reduction in the mitochondria of apicomplexan parasites.

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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018influential citation
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  2017cites this paper
• Properties of anaerobic fungi isolated from several habitats: complexity of phenotypes.

  2016cites this paper
• Microbial acetyl-CoA metabolism and metabolic engineering.

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• Diversity and origins of anaerobic metabolism in mitochondria and related organelles

  2015cites this paper
• A SUF Fe-S cluster biogenesis system in the mitochondrion-related organelles of the anaerobic protist Pygsuia.

  2014cites this paper
• Functional and comparative analysis of novel dehydrogenase genes in Carboxydothermus hydrogenoformans Z-2901

  2013cites this paper
• Anaerobic energy metabolism in unicellular photosynthetic eukaryotes.

  2013cites this paper
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  2012cites this paper
• The Organellar Genome and Metabolic Potential of the Hydrogen-Producing Mitochondrion of Nyctotherus ovalis

  2011cites this paper
• Eukaryotic pyruvate formate lyase and its activating enzyme were acquired laterally from a Firmicute.

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• Phylogenetic distributions and histories of proteins involved in anaerobic pyruvate metabolism in eukaryotes.

  2010cites this paper
• Diversity and reductive evolution of mitochondria among microbial eukaryotes

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• The Possible Involvement of Copper-Containing Nitrite Reductase (NirK) and Flavohemoglobin in Denitrification by the Fungus Cylindrocarpon tonkinense

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• Cellular Origin , Life in Extreme Habitats and Astrobiology

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• A mitochondrial origin for hydrogenosomes

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• Analysis of Functional Genes in Carbohydrate Metabolic Pathway of Anaerobic Rumen Fungus Neocallimastix frontalis PMA02

  2009influential citation
• Hydrogenosomes and Mitosomes: Conservation and Evolution of Functions

  2009cites this paper
• Hydrogenosomes and Mitosomes: Conservation and Evolution of Functions 1

  2009cites this paper
• Hydrogenosomes of Anaerobic Chytrids: An Alternative Way to Adapt to Anaerobic Environments

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• Biochemical and Physiological Characterization of the Pyruvate Formate-Lyase Pfl1 of Chlamydomonas reinhardtii, a Typically Bacterial Enzyme in a Eukaryotic Alga

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• The Cellulase/Hemicellulase System of the Anaerobic FungusOrpinomycesPC‐2 and Aspects of Its Applied Use

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• Culture in vitro et caractérisation d'enzymes hydrogénosomales chez Histomonas meleagridis, protozoaire flagellé parasite de gallinacés

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• Image segmentation and lightness perception

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• Hydrogenosomes evolved repeatedly

  2004cites this paper
• The origins of hydrogenosomes

  2004influential citation
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• Genomic DNA analysis of genes encoding (hemi-)cellulolytic enzymes of the anaerobic fungus Piromyces sp. E2.

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• Hydrogenases and Hydrogen Metabolism of Cyanobacteria

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• Classi¢cation and phylogeny of hydrogenases 1

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• Hydrogenosomes: convergent adaptations of mitochondria to anaerobic environments.

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• Origins of hydrogenosomes and mitochondria.

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• Origin and Evolution of the Mitochondrial Proteome

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