An updated review of pediatric drug‐induced sleep endoscopy

Drug‐induced sleep endoscopy (DISE) involves assessment of the upper airway using a flexible endoscope while patients are in a pharmacologically‐induced sleep‐like state. The aim of this article is to review the current literature regarding the role of DISE in children with obstructive sleep apnea (OSA). The indications, typical anesthetic protocol, comparison to other diagnostic modalities, scoring systems, and outcomes are discussed.

• Publication year

  2017

• Venue

  Laryngoscope Investigative Otolaryngology

• Publication date

  2017-11-02

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/lio2.118PMID 29299518PMCID 5743164
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Outcomes of Drug-Induced Sleep Endoscopy–Directed Surgery for Pediatric Obstructive Sleep Apnea

  2018cited by this paper
• The current state of pediatric drug‐induced sleep endoscopy

  2017influential reference
• Sedative choice in drug‐induced sleep endoscopy: A neuropharmacology‐based review

  2017cited by this paper
• Does drug-induced sleep endoscopy change the surgical decision in surgically naïve non-syndromic children with snoring/sleep disordered breathing from the standard adenotonsillectomy? A retrospective cohort study

  2017cited by this paper
• Drug-induced sedation endoscopy in children <2 years with obstructive sleep apnea syndrome: upper airway findings and treatment outcomes

  2017cited by this paper
• Multimodality assessment of upper airway obstruction in children with persistent obstructive sleep apnea after adenotonsillectomy

  2017cited by this paper
• Clinically small tonsils are typically not obstructive in children during drug‐induced sleep endoscopy

  2017cited by this paper
• Drug-induced sleep endoscopy in children with Prader-Willi syndrome

  2016cited by this paper
• Drug-Induced Sleep Endoscopy.

  2016cited by this paper
• Surgical outcomes and sleep endoscopy for children with sleep-disordered breathing and hypotonia.

  2016cited by this paper
• Drug-induced sleep-endoscopy in children's sleep related breathing disorders.

  2016cited by this paper
• Obstructive Sleep Apnea Resolution in Hypopnea- versus Apnea-Predominant Children after Adenotonsillectomy

  2016cited by this paper
• Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea

  2016cited by this paper
• Drug-induced sedation endoscopy in surgically naive children with Down syndrome and obstructive sleep apnea.

  2016cited by this paper
• Correlates of Pediatric CPAP Adherence

  2016cited by this paper
• The effects of Anesthesia and opioids on the upper airway: A systematic review

  2016influential reference
• Comparison of the combination of dexmedetomidine and ketamine to propofol or propofol/sevoflurane for drug‐induced sleep endoscopy in children

  2016cited by this paper
• Systematic review of site of obstruction identification and non‐CPAP treatment options for children with persistent pediatric obstructive sleep apnea

  2016cited by this paper
• Drug-Induced Sleep-Endoscopy in Children's Sleep Related Breathing Disorders

  2016cited by this paper
• Assessment of pediatric obstructive sleep apnea using a drug‐induced sleep endoscopy rating scale

  2016cited by this paper
• Drug induced sleep endoscopy in the decision-making process of children with obstructive sleep apnea.

  2015cited by this paper
• Bispectral Index in Evaluating Effects of Sedation Depth on Drug-Induced Sleep Endoscopy

  2015cited by this paper
• Supraglottoplasty for sleep endoscopy diagnosed sleep dependent laryngomalacia.

  2015cited by this paper
• Drug-induced sedation endoscopy in pediatric obstructive sleep apnea syndrome.

  2014cited by this paper
• Identifying a rapid bolus dose of dexmedetomidine (ED50) with acceptable hemodynamic outcomes in children

  2014cited by this paper
• A new scoring system for upper airway pediatric sleep endoscopy.

  2014cited by this paper
• European position paper on drug-induced sedation endoscopy (DISE)

  2014cited by this paper
• Beyond adenotonsillectomy: outcomes of sleep endoscopy-directed treatments in pediatric obstructive sleep apnea.

  2014cited by this paper
• Awake versus drug‐induced sleep endoscopy: Evaluation of airway obstruction in obstructive sleep apnea/hypopnoea syndrome

  2013cited by this paper
• Quality of life impairment in patients of obstructive sleep apnea and its relation with the severity of disease

  2013cited by this paper
• Fiber-optic sleep endoscopy in children with persistent obstructive sleep apnea: inter-observer correlation and comparison with awake endoscopy.

  2013cited by this paper
• A randomized trial of adenotonsillectomy for childhood sleep apnea.

  2013cited by this paper
• Respiratory Indications for Polysomnography in Children

  2012cited by this paper
• Drug-induced sleep endoscopy in persistent pediatric sleep-disordered breathing after adenotonsillectomy.

  2012cited by this paper
• Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome

  2012cited by this paper
• Upper airway findings in children with Down syndrome on sleep nasopharyngoscopy: case-control study.

  2012cited by this paper
• Supraglottoplasty for occult laryngomalacia to improve obstructive sleep apnea syndrome.

  2012cited by this paper
• Novel Grading System for Quantifying Upper-Airway Obstruction on Sleep Endoscopy

  2012cited by this paper
• Sleep Endoscopy in the Evaluation of Pediatric Obstructive Sleep Apnea

  2012influential reference
• Clinical Practice Guideline: Polysomnography for Sleep-Disordered Breathing Prior to Tonsillectomy in Children

  2011cited by this paper
• Drug-induced sleep endoscopy: the VOTE classification

  2011cited by this paper
• Practice parameters for the respiratory indications for polysomnography in children.

  2011cited by this paper
• Clinical Practice Guideline: Tonsillectomy in Children

  2010cited by this paper
• Propofol-induced sleep: Polysomnographic evaluation of patients with obstructive sleep apnea and controls

  2010cited by this paper
• Prevalence of laryngomalacia in children presenting with sleep‐disordered breathing

  2010influential reference
• Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study.

  2010influential reference
• Interrater reliability of drug-induced sleep endoscopy.

  2010cited by this paper
• Evolution of Changes in Upper Airway Collapsibility during Slow Induction of Anesthesia with Propofol

  2009cited by this paper
• Test-retest reliability of drug-induced sleep endoscopy

  2009cited by this paper
• Sleep, sleep disorders and inflammation in children.

  2009cited by this paper
• Cardiovascular complications of obstructive sleep apnea syndrome: evidence from children.

  2009cited by this paper
• Adenotonsillectomy for obstructive sleep apnea in obese children: A meta-analysis

  2009cited by this paper
• Asthma as a Predictor of Obstructive Sleep Apnea in Urban African-American Children

  2009cited by this paper
• Ambulatory blood pressure in children with obstructive sleep apnoea: a community based study

  2008cited by this paper
• Pediatric obstructive sleep apnea: complications, management, and long-term outcomes.

  2008cited by this paper
• Pediatric obstructive sleep apnea and quality of life: A meta-analysis

  2008cited by this paper
• Preoperative continuous positive airway pressure compliance in children with obstructive sleep apnea syndrome: assessed by a simplified approach.

  2008cited by this paper
• Epidemiology of pediatric obstructive sleep apnea.

  2008cited by this paper
• Late-onset laryngomalacia: a variant of disease.

  2008cited by this paper
• Outcome of Adenotonsillectomy for Obstructive Sleep Apnea in Obese and Normal-Weight Children

  2007cited by this paper
• Adenotonsillectomy for Obstructive Sleep Apnea in Children: Outcome Evaluated by Pre‐ and Postoperative Polysomnography

  2007cited by this paper
• Reduced Time in Bed and Obstructive Sleep-Disordered Breathing in Children Are Associated With Cognitive Impairment

  2007cited by this paper
• Obesity increases the risk for persisting obstructive sleep apnea after treatment in children.

  2006cited by this paper
• Persistence of obstructive sleep apnea syndrome in children after adenotonsillectomy.

  2006cited by this paper
• Behavior, neurocognition and quality-of-life in children with sleep-disordered breathing.

  2006cited by this paper
• Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls

  2006cited by this paper
• Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults.

  2006cited by this paper
• The Effectiveness of Tonsillectomy and Adenoidectomy in the Treatment of Pediatric Obstructive Sleep Apnea/Hypopnea Syndrome: A Meta-Analysis

  2006cited by this paper
• Neurobehavioral implications of habitual snoring in children.

  2004cited by this paper
• Cine Magnetic Resonance Imaging: Evaluation of Persistent Airway Obstruction after Tonsil and Adenoidectomy in Children with Down Syndrome

  2004cited by this paper
• Outcome of adenotonsillectomy for obstructive sleep apnea in children under 3 years

  2004influential reference
• The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects.

  2003cited by this paper
• Clinical practice guideline: diagnosis and management of childhood obstructive sleep apnea syndrome.

  2002cited by this paper
• Clinical practice guideline: diagnosis and management of childhood obstructive sleep apnea syndrome.

  2002cited by this paper
• The use of diagnostic sleep nasendoscopy in the management of children with complex upper airway obstruction.

  2000cited by this paper
• Sleep nasendoscopy: a technique of assessment in snoring and obstructive sleep apnoea.

  1991cited by this paper
• Endoscopic evaluation and treatment of sleep-associated upper airway obstruction in infants and young children.

  1990cited by this paper
• Dexmedetomidine produces a hypnotic-anesthetic action in rats via activation of central alpha-2 adrenoceptors.

  1989cited by this paper
• The (cid:1) 2 -Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects

  year unknowncited by this paper
• Supraglottoplasty for Occult Laryngomalacia to Improve Obstructive Sleep Apnea Syndrome ; How- Ever, Objective Improvement in the Cohort

  year unknowncited by this paper

• Active strategies for children with obstructive sleep-disordered breathing: a systematic review and meta-analysis.

  2026cites this paper
• Drug-induced sleep endoscopy (DISE): a retrospective review in Western Australian children

  2025cites this paper
• Evaluation of Sleep Stages During Drug‐Induced Sleep Endoscopy in Pediatric Patients with Obstructive Sleep Apnea: A Pilot Study

  2025cites this paper
• Minimal to Mean Airway Area Ratio of the Pharynx: A Novel Predictor of Pediatric Obstructive Sleep Apnea in Three‐Dimensional Imaging

  2025cites this paper
• [Progress in the application of drug-induced sleep endoscopy in pediatric OSA].

  2025cites this paper
• Does drug induced sleep endoscopy induce upper airway obstruction?

  2025cites this paper
• Surgical Management of Pediatric Obstructive Sleep Apnea Beyond T&A - Tongue Base and Larynx.

  2024cites this paper
• Surgical Management of Pediatric Obstructive Sleep Apnea Beyond Tonsillectomy & Adenoidectomy: Tongue Base and Larynx.

  2024cites this paper
• Surgical Management of Pediatric Obstructive Sleep Apnea Beyond Adenotonsillectomy: The Nose, Nasopharynx, and Palate.

  2024cites this paper
• Drug Induced Sleep Endoscopy (DISE): An Upcoming Modality for Obstructive Sleep Disordered Breathing in Infants

  2024cites this paper
• Amygdalectomie chez l’enfant

  2023cites this paper
• Expert Consensus Statement: Management of Pediatric Persistent Obstructive Sleep Apnea After Adenotonsillectomy.

  2023cites this paper
• Drug‐Induced sleep endoscopy in children: NAVOTEL scoring system development

  2023influential citation
• Findings on drug-induced sleep endoscopy in infants with laryngomalacia.

  2023cites this paper
• Effects of drug-induced sleep endoscopy in children with conventional obstructive sleep apnea–hypopnea syndrome: a systematic review and meta-analysis

  2023cites this paper
• Management of Persistent, Post-adenotonsillectomy Obstructive Sleep Apnea in Children: An Official American Thoracic Society Clinical Practice Guideline

  2023cites this paper
• Obstructive Sleep-Disordered Breathing in Infants with Normal Awake Clinical Examination: Contribution of Drug-Induced Sleep Endoscopy

  2023cites this paper
• Development and validation of the international pediatric sleep endoscopy scale (IPSES).

  2023cites this paper
• Efficacy of adenotonsillectomy on pediatric obstructive sleep apnea and related outcomes: A narrative review of current evidence.

  2023cites this paper
• Drug-Induced Sleep Endoscopy in Children

  2023cites this paper
• The Role of Epiglottopexy for Pediatric OSA

  2023cites this paper
• Diagnosis of Paediatric Obstructive Sleep-Disordered Breathing beyond Polysomnography

  2023cites this paper
• Sleep Endoscopy and Cine Magnetic Resonance Imaging Evaluation of Children With Persistent Obstructive Sleep Apnea.

  2022cites this paper
• Tonsillectomy in Children with 22q11.2 Deletion Syndrome

  2022cites this paper
• Pediatric Drug-Induced Sleep Endoscopy.

  2022cites this paper
• International Consensus Statement on Obstructive Sleep Apnea

  2022cites this paper
• Reliability of a pediatric sleep endoscopy scoring system.

  2022cites this paper
• Use of VOTE score in predicting outcomes in pediatric obstructive sleep apnea.

  2022cites this paper
• Cardiac arrhythmias in an infant with obstructive sleep apnea syndrome

  2022cites this paper
• Management of Pediatric Obstructive Sleep Apnea After Failed Tonsillectomy and Adenoidectomy.

  2022cites this paper
• Outcome of CPAP Titration for Moderate-to-Severe OSA Under Drug-Induced Sleep Endoscopy: A Randomized Controlled Crossover Trial

  2022cites this paper
• Breathing Abnormalities During Sleep and Wakefulness in Rett Syndrome: Clinical Relevance and Paradoxical Relationship With Circulating Pro-oxidant Markers

  2022cites this paper
• Pediatric drug-induced sleep endoscopy: An updated review of the literature

  2021cites this paper
• Expert Consensus Statement: Pediatric Drug-Induced Sleep Endoscopy

  2021cites this paper
• Persistent Obstructive Sleep Apnea Burden on Family Finances and Quality of Life

  2021influential citation
• Utility of sleep nasendoscopy versus microlaryngotracheobronchoscopy in the diagnosis of paediatric upper airway obstruction

  2021cites this paper
• Paediatrics: how to manage obstructive sleep apnoea syndrome

  2021cites this paper
• ENT Management of Obstructive Sleep Apnea

  2021cites this paper
• Evaluation of Agreement on Presence and Severity of Tracheobronchomalacia by Dynamic Flexible Bronchoscopy.

  2021cites this paper
• Surgical Treatment of Pediatric Obstructive Sleep Apnea

  2021cites this paper
• Pediatric OSA: Evidence-Based Review of Treatment Results

  2021cites this paper
• Update and Progress in Pediatric Sleep Disorders.

  2021cites this paper
• Sleep Endoscopy Findings in Children With Obstructive Sleep Apnea and Small Tonsils

  2021cites this paper
• Anestesia del niño en otorrinolaringología

  2021cites this paper
• Anestesia del bambino in oto-rino-laringoiatria

  2021cites this paper
• 21 Pediatric Sleep Endoscopy Pediatric sleep endoscopy,

  2021cites this paper
• [Features of sleependoscopy in children].

  2021cites this paper
• Review findings of drug-induced sleep endoscopy (DISE) in children with obstructive sleep apnea (OSA)

  2021cites this paper
• Anesthésie de l’enfant en oto-rhino-laryngologie

  2021cites this paper
• Pediatric Drug-Induced Sleep Endoscopy: Technique and Scoring System

  2020cites this paper
• Respiratory and hemodynamic effects of three different sedative regimens for drug induced sleep endoscopy in sleep apnea patients. A prospective randomized study.

  2020cites this paper
• Outcome of drug induced sleep endoscopy directed surgery in paediatrics obstructive sleep apnoea: A systematic review.

  2020cites this paper
• Upper Airway Anatomy and Physiology

  2020cites this paper
• The impact of persistent pediatric obstructive sleep apnea on the Quality of Life of Patients' families.

  2020cites this paper
• Management of A‐Frame Tracheal Deformity in Children With Endoscopic Resection Tracheoplasty

  2020cites this paper
• Pediatric obstructive sleep apnea revisited: Perioperative considerations for the pediatric Anesthesiologist.

  2020cites this paper
• Outcomes of OSA in surgically naïve young children with and without DISE identified laryngomalacia.

  2020cites this paper
• Management of obstructive sleep apnea in children with achondroplasia: Outcomes of surgical interventions.

  2020cites this paper
• International Pediatric Otolaryngology group (IPOG) consensus on the diagnosis and management of pediatric obstructive sleep apnea (OSA).

  2020cites this paper
• Obstructive Sleep Apnea with Paradoxical Vocal Cord Movement in Children during Sleep Endoscopy: Case Series

  2020cites this paper
• Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea

  2020influential citation
• Sleep endoscopy findings in children in supine versus left lateral position.

  2020cites this paper
• Effectiveness of pediatric drug-induced sleep endoscopy for REM-predominant obstructive sleep apnea

  2020cites this paper
• The Emerging Role of Drug-Induced Sleep Endoscopy in the Management of Obstructive Sleep Apnea

  2020cites this paper
• Evaluation and Management of Children with Obstructive Sleep Apnea Syndrome

  2020cites this paper
• Anesthesia for shared airway surgery in children

  2020cites this paper
• Anesthetic management of children undergoing drug-induced sleep endoscopy: A retrospective review.

  2020cites this paper
• Cornelia de lange manifestations in otolaryngology: A systematic review and meta‐analysis

  2020cites this paper
• Sleep-Disordered Breathing in Children

  2019cites this paper
• The Effect of Cleft Palate Repair on Polysomnography Results

  2019cites this paper
• Apport de l’endoscopie sous sommeil induit dans la prise en charge du syndrome d’apnées-hypopnées obstructives du sommeil chez l’enfant

  2019cites this paper
• Preoperative identification of children at high risk of obstructive sleep apnea

  2019cites this paper
• Safety and cost of drug‐induced sleep endoscopy outside the operating room

  2019influential citation
• Drug-induced sleep endoscopy compared with systematic adenotonsillectomy in the management of obstructive sleep apnoea in children: a systematic review and meta-analysis protocol

  2019cites this paper
• Rôle de l’ORL dans le diagnostic du syndrome d’apnée-hypopnée obstructive du sommeil (SAHOS) de l’enfant. Deuxième partie. Les examens complémentaires en dehors des enregistrements du sommeil

  2019cites this paper
• Managing the Child with Persistent Sleep Apnea.

  2019cites this paper
• Guidelines of the French Society of Otorhinolaryngology. Role of the ENT specialist in the diagnosis of obstructive sleep apnea-hypopnea syndrome (OSAHS) in children. Part 2: Diagnostic investigations apart from sleep studies.

  2019cites this paper
• Evolution of Anesthesia for Pediatric Airway Surgery: From Ether to TIVA and Current Controversies

  2019cites this paper
• Outcome of drug-induced sleep endoscopy-directed surgery for persistent obstructive sleep apnea after adenotonsillar surgery.

  2019cites this paper
• Contribution of drug-induced sleep endoscopy to the management of pediatric obstructive sleep apnea/hypopnea syndrome.

  2019cites this paper
• Adenotonsillectomy in Pediatric OSA: Time to Look Elsewhere

  2018cites this paper
• Techniques for evaluation and management of tongue-base obstruction in pediatric obstructive sleep apnea

  2018cites this paper
• The shifting relationship between weight and pediatric obstructive sleep apnea: A historical review

  2018cites this paper
• Screening for obstructive sleep apnoea (OSA) in children—methodological considerations

  2018cites this paper
• Plenary sessions

  2018cites this paper
• The Effect of Cleft Palate Repair on Polysomnography Results.

  2017cites this paper