Characterization of cis‐regulatory elements conferring mercury‐induced interleukin‐4 gene expression in rat mast cells: a role for signal transducer and activator of transcription 6 and TATA box binding sites

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Immunology

• Publication date

  2009-08-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1365-2567.2008.03023.xPMID 19604304PMCID PMC2729530
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transcriptional Control of Gene Expression

  2018cited by this paper
• In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

  2008cited by this paper
• Selective Activation of Fyn/PI3K and p38 MAPK Regulates IL-4 Production in BMMC under Nontoxic Stress Condition1

  2007cited by this paper
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  2005cited by this paper
• NF-kappa B synergizes with NF-AT and NF-IL6 in activation of the IL-4 gene in T cells.

  2004cited by this paper
• Mast cells in innate immunity.

  2004cited by this paper
• Regulation of STAT signalling by proteolytic processing.

  2004cited by this paper
• NF‐κB synergizes with NF‐AT and NF‐IL6 in activation of the IL‐4 gene in T cells

  2004cited by this paper
• Oxidative stress stimulates IL‐4 and IL‐6 production in mast cells by an APE/Ref‐1‐dependent pathway

  2003cited by this paper
• Proteolytic Processing of Stat6 Signaling in Mast Cells as a Negative Regulatory Mechanism

  2002cited by this paper
• Mast cell-restricted p70 Stat6 isoform is a product of selective proteolysis.

  2002cited by this paper
• Antioxidants inhibit mercuric chloride-induced early vasculitis.

  2002cited by this paper
• Vitamin E inhibits IL‐4 gene expression in peripheral blood T cells

  2002cited by this paper
• IL-4 Induces the Proteolytic Processing of Mast Cell STAT61

  2002cited by this paper
• Stat6 Is Necessary and Sufficient for IL-4’s Role in Th2 Differentiation and Cell Expansion

  2001cited by this paper
• IL-4 gene expression up-regulated by mercury in rat mast cells: a role of oxidant stress in IL-4 transcription.

  2001cited by this paper
• Vav Synergizes with Protein Kinase CΘ to Mediate IL-4 Gene Expression in Response to CD28 Costimulation in T Cells1

  2000cited by this paper
• Mast cells in innate immunity

  2000cited by this paper
• Presentation of IFN-γ to Nitric Oxide-Producing Cells: A Novel Function for Mast Cells1

  2000cited by this paper
• Characterization of P5, a novel NFAT/AP-1 site in the human IL-4 promoter.

  2000cited by this paper
• Senescent Jejunal Mast Cells and Eosinophils in the Mouse Preferentially Translocate to the Spleen and Draining Lymph Node, Respectively, During the Recovery Phase of Helminth Infection1

  2000cited by this paper
• Presentation of IFN-gamma to nitric oxide-producing cells: a novel function for mast cells.

  2000cited by this paper
• Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells.

  1999cited by this paper
• Is NF-kappaB the sensor of oxidative stress?

  1999cited by this paper
• STAT6‐independent production of IL‐4 by mast cells

  1999cited by this paper
• Transcription factors in lymphocyte development--T and B cells get together.

  1999cited by this paper
• Mercuric Chloride–Induced Autoimmunity

  1999cited by this paper
• Sendai Virus and Simian Virus 5 Block Activation of Interferon-Responsive Genes: Importance for Virus Pathogenesis

  1999cited by this paper
• IL-4 preferentially activates a novel STAT6 isoform in mast cells.

  1999cited by this paper
• Activators and target genes of Rel/NF-kappaB transcription factors.

  1999cited by this paper
• Is NF‐κB the sensor of oxidative stress?

  1999cited by this paper
• Early vasculitis in the mercuric chloride induced Brown Norway rat model is neutrophil independent

  1999cited by this paper
• IL‐4 mRNA transcription is induced in mouse bone marrow‐derived mast cells through an MHC class II‐dependent signaling pathway

  1998cited by this paper
• Mast cell activation and migration to lymph nodes during induction of an immune response in mice.

  1998cited by this paper
• Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription

  1998cited by this paper
• Signal Transducer and Activator of Transcription Factor 6 (Stat6)-deficient Mice Are Protected from Antigen-induced Airway Hyperresponsiveness and Mucus Production

  1998cited by this paper
• Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation.

  1998cited by this paper
• Involvement of Jun and Rel Proteins in Up-regulation of Interleukin-4 Gene Activity by the T Cell Accessory Molecule CD28*

  1998cited by this paper
• Functions of IL-4 and control of its expression.

  1997cited by this paper
• The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells.

  1997cited by this paper
• Mast cells.

  1997cited by this paper
• Mercuric chloride-induced vasculitis in the Brown Norway rat: alpha beta T cell-dependent and -independent phases: role of the mast cell.

  1997cited by this paper
• Alterations in intracellular reactive oxygen species generation and redox potential modulate mast cell function

  1997cited by this paper
• Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

  1996cited by this paper
• Essential role of Stat6 in IL-4 signalling

  1996cited by this paper
• The strain difference in the effect of mercuric chloride on antigen‐triggered serotonin release from rat mast cells is not mediated via interferon‐γ

  1996cited by this paper
• The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

  1996cited by this paper
• Mast cells process bacterial Ags through a phagocytic route for class I MHC presentation to T cells.

  1996cited by this paper
• Cytokine transcriptional events during helper T cell subset differentiation

  1996cited by this paper
• The two faces of the mast cell

  1996cited by this paper
• The time course and characterization of mercuric chloride-induced immunopathology in the brown Norway rat.

  1995cited by this paper
• Mast cells: the neuroimmune connection.

  1995cited by this paper
• Nuclear factor-IL6 activates the human IL-4 promoter in T cells.

  1995cited by this paper
• Compounds that induce autoimmunity in the Brown Norway rat sensitize mast cells for mediator release and interleukin‐4 expression

  1995cited by this paper
• Mast Cells: The Neuroimmune Connection (Part 1 of 2)

  1995cited by this paper
• Interleukin‐4 Gene Expression in Mercury‐Induced Autoimmunity

  1995cited by this paper
• Inflammatory polyarthritis induced by mercuric chloride in the Brown Norway rat.

  1995cited by this paper
• Autoantibodies to myeloperoxidase in brown Norway rats treated with mercuric chloride.

  1992cited by this paper
• Mercuric chloride-treated brown Norway rats develop widespread tissue injury including necrotizing vasculitis.

  1992cited by this paper
• Mercuric chloride-induced autoimmunity.

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• [The mast cell].

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• Autoreactive T cells in mercury-induced autoimmunity. Ability to induce the autoimmune disease.

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• Get together

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• Immune type glomerulonephritis induced by HgCl2 in the Brown Norway rat.

  1978cited by this paper
• Demonstration of antinuclear antibodies in mercuric chloride-induced glomerulopathy in the rat.

  1978cited by this paper

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  2015cites this paper
• Autoimmunity-inducing metals (Hg, Au and Ag) modulate mast cell signaling, function and survival.

  2011cites this paper
• The role of T-helper cells in atherosclerosis.

  2011cites this paper
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  2010cites this paper