Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  American Journal of Hypertension

• Publication date

  2004-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.AMJHYPER.2003.10.006PMID 14751661
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Angiotensin converting enzyme inhibition prevents development of muscle and nerve dysfunction and stimulates angiogenesis in streptozotocin-diabetic rats

  2004cited by this paper
• Modulation of metabolic control by angiotensin converting enzyme (ACE) inhibition

  2003cited by this paper
• Cardiovascular protective role of a low-dose antihypertensive combination in obese Zucker rats

  2003cited by this paper
• Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis.

  2002cited by this paper
• Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo.

  2002cited by this paper
• Endothelial Nitric Oxide Synthase Lies Downstream From Angiotensin II–Induced Angiogenesis in Ischemic Hindlimb

  2002cited by this paper
• Very-Low-Dose Combination of the Angiotensin-Converting Enzyme Inhibitor Perindopril and the Diuretic Indapamide Induces an Early and Sustained Increase in Neovascularization in Rat Ischemic Legs

  2002cited by this paper
• Antiangiogenic Effect of Angiotensin II Type 2 Receptor in Ischemia-Induced Angiogenesis in Mice Hindlimb

  2002cited by this paper
• ACE Inhibitor Improves Insulin Resistance in Diabetic Mouse Via Bradykinin and NO

  2002cited by this paper
• Decreased Cardiac Expression of Vascular Endothelial Growth Factor and Its Receptors in Insulin-Resistant and Diabetic States: A Possible Explanation for Impaired Collateral Formation in Cardiac Tissue

  2002cited by this paper
• Perindopril Alters Vascular Angiotensin-Converting Enzyme, AT1 Receptor, and Nitric Oxide Synthase Expression in Patients With Coronary Heart Disease

  2002cited by this paper
• Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo

  2002cited by this paper
• Vascular growth factor expression in a rat model of severe limb ischemia.

  2002cited by this paper
• Angiotensin II Angiogenic Effect In Vivo Involves Vascular Endothelial Growth Factor- and Inflammation-Related Pathways

  2002cited by this paper
• Role of ANG II in coronary capillary angiogenesis at the insulin-resistant stage of a NIDDM rat model.

  2002cited by this paper
• Insulin resistance and cardiovascular disease.

  2001cited by this paper
• Coronary capillary remodeling in non-insulin-dependent diabetic rats: amelioration by inhibition of angiotensin converting enzyme and its potential clinical implications.

  2001cited by this paper
• The effects of insulin and beta-adrenergic stimulation on glucose transport, glut 4 and PKB activation in the myocardium of lean and obese non-insulin dependent diabetes mellitus rats.

  2001cited by this paper
• Proangiogenic Effect of Angiotensin-Converting Enzyme Inhibition Is Mediated by the Bradykinin B2 Receptor Pathway

  2001cited by this paper
• Angiotensin-converting enzyme inhibition improves defective angiogenesis in the ischemic limb of spontaneously hypertensive rats.

  2001cited by this paper
• The effects of insulin and β-adrenergic stimulation on glucose transport, glut 4 and PKB activation in the myocardium of lean and obese non-insulin dependent diabetes mellitus rats

  2001cited by this paper
• Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells.

  2000cited by this paper
• Lipotoxic heart disease in obese rats: implications for human obesity.

  2000cited by this paper
• Insulin and Insulin-like Growth Factor-I Induce Vascular Endothelial Growth Factor mRNA Expression via Different Signaling Pathways*

  2000cited by this paper
• Insulin resistance and cardiovascular disease.

  2000cited by this paper
• The effects of an angiotensin-converting enzyme inhibitor and an angiotensin II receptor antagonist on insulin resistance in fructose-fed rats.

  2000cited by this paper
• Tissue inhibition of angiotensin-converting enzyme activity stimulates angiogenesis in vivo.

  1999cited by this paper
• Defective dopamine receptor function in proximal tubules of obese zucker rats.

  1999cited by this paper
• Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.

  1999cited by this paper
• Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells.

  1999cited by this paper
• Altered pressure-natriuresis in obese Zucker rats.

  1999cited by this paper
• Cardiac microvasculature in DOCA-salt hypertensive rats : effect of endothelin ET(A) receptor antagonism.

  1999cited by this paper
• Cardiovascular effects of captopril and enalapril in obese Zucker rats.

  1999cited by this paper
• ACE inhibition but not angiotensin II antagonism reduces plasma fibrinogen and insulin resistance in overweight hypertensive patients.

  1998cited by this paper
• Differences in tissue angiotensin II-forming pathways by species and organs in vitro.

  1998cited by this paper
• ACE inhibitors promote nitric oxide accumulation to modulate myocardial oxygen consumption.

  1997cited by this paper
• Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations.

  1997cited by this paper
• Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.

  1997cited by this paper
• Insulin sensitizer YM268 ameliorates insulin resistance by normalizing the decreased content of GLUT4 in adipose tissue of obese Zucker rats.

  1997cited by this paper
• Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats.

  1997cited by this paper
• Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats.

  1997cited by this paper
• Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure.

  1997cited by this paper
• Molecular analysis of insulin resistance in isolated ventricular cardiomyocytes of obese Zucker rats.

  1997cited by this paper
• Vascular and cardiac protection by ramipril in spontaneously hypertensive rats: prevention versus regression study.

  1996cited by this paper
• Insulin-Induced Glucose Transporter (GLUT1 and GLUT4) Translocation in Cardiac Muscle Tissue Is Mimicked by Bradykinin

  1996cited by this paper
• Capillary surface area is reduced and tissue thickness from capillaries to myocytes is increased in the left ventricle of streptozotocin-diabetic rats

  1995cited by this paper
• Effects of captopril on glucose transport activity in skeletal muscle of obese Zucker rats.

  1995cited by this paper
• Antihypertensive therapy with enalapril improves glucose storage and insulin sensitivity in hypertensive patients with non-insulin-dependent diabetes mellitus.

  1995cited by this paper
• Effects of Genetic Hyperinsulinaemia on Vascular Reactivity, Blood Pressure, and Renal Structure in the Zucker Rat

  1995cited by this paper
• Effect on insulin sensitivity of angiotensin converting enzyme inhibitors with or without a sulphydryl group: Bradykinin may improve insulin resistance in dogs and humans

  1994cited by this paper
• Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.

  1994cited by this paper
• Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism.

  1994cited by this paper
• Decreased peripheral blood flow in the pathogenesis of the metabolic syndrome comprising hypertension, hyperlipidemia, and hyperinsulinemia.

  1993cited by this paper
• The Zucker Fatty Rat as a Genetic Model of Obesity and Hypertension

  1989cited by this paper
• Neuroendocrine and metabolic basis of type II diabetes as studied in animal models.

  1988cited by this paper
• Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

  1981cited by this paper

• Expanding landscape of coronary microvascular disease in co-morbid conditions: Metabolic disease and beyond.

  2024cites this paper
• Gender Differences in the Impact of a High-Fat, High-Sugar Diet in Skeletal Muscles of Young Female and Male Mice

  2024cites this paper
• Female and male obese Zucker rats display differential inflammatory mediator and long non-coding RNA profiles.

  2023cites this paper
• Pharmacological inhibition of the lipid phosphatase PTEN ameliorates heart damage and adipose tissue inflammation in stressed rats with metabolic syndrome

  2022cites this paper
• Capillaries as a Therapeutic Target for Heart Failure

  2022cites this paper
• Endothelial Autophagy in Coronary Microvascular Dysfunction and Cardiovascular Disease

  2022cites this paper
• Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure

  2021cites this paper
• Inflammation in Metabolic Cardiomyopathy

  2021cites this paper
• Mechanobiology of Microvascular Function and Structure in Health and Disease: Focus on the Coronary Circulation

  2021cites this paper
• Recovery of Ggt7 and Ace Expressions in the Colon Alleviates Collagen-Induced Arthritis in Rats by Specific Bioactive Polysaccharide Intervention.

  2020cites this paper
• Capillary Rarefaction in Obesity and Metabolic Diseases—Organ-Specificity and Possible Mechanisms

  2020cites this paper
• Microvascular Dysfunction in Diabetes Mellitus and Cardiometabolic Disease.

  2020cites this paper
• Vascularisation of Skeletal Muscle

  2019cites this paper
• Effects of Angiotensin-Converting Enzyme Inhibition on Circulating Endothelial Progenitor Cells in Patients with Acute Ischemic Stroke

  2018cites this paper
• ВАСКУЛОЕНДОТЕЛІАЛЬНИЙ ФАКТОР РОСТУ А ТА ПОЛІМОРФІЗМ G634C ГЕНА ВЕФР-A У ХВОРИХ ІНФАРКТОМ МІОКАРДА В ГОСТРИЙ ТА ВІДДАЛЕНИЙ ПЕРІОДИ

  2018cites this paper
• ВАСКУЛОЕНДОТЕЛІАЛЬНИЙ ФАКТОР РОСТУ А ТА ПОЛІМОРФІЗМ G634C ГЕНА ВЕФР-A У ХВОРИХ ІНФАРКТОМ МІОКАРДА В ГОСТРИЙ ТА ВІДДАЛЕНИЙ ПЕРІОДИ

  2018cites this paper
• Exercise Training Restores the Cardiac Microrna-16 Levels Preventing Microvascular Rarefaction in Obese Zucker Rats

  2018cites this paper
• Beneficial effects of renal denervation on cardiac angiogenesis in rats with prolonged pressure overload

  2017cites this paper
• An overview of the inflammatory signalling mechanisms in the myocardium underlying the development of diabetic cardiomyopathy.

  2017cites this paper
• Murine Models of Heart Failure With Preserved Ejection Fraction

  2017cites this paper
• Morphological quantification of myocardial pathology in the Zucker diabetic fatty rat

  2016cites this paper
• [Renovascular effects of antiangiogenic drugs].

  2016cites this paper
• Effets rénovasculaires des antiangiogéniques

  2016cites this paper
• Macrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis

  2016cites this paper
• Role of miR-199b-5p in regulating angiogenesis in mouse myocardial microvascular endothelial cells through HSF1/VEGF pathway.

  2016cites this paper
• Effects of angiotensin-converting enzyme inhibition and bradykinin peptides in rats with myocardial infarction.

  2015cites this paper
• Original Article Effects of angiotensin-converting enzyme inhibition and bradykinin peptides in rats with myocardial infarction

  2015cites this paper
• mobility in overweight and obese older adults: a randomized controlled trial Effects of resistance training with and without caloric restriction on physical function and

  2015cites this paper
• In reply to: Enalapril and the VEGFA gene: personalized medicine in hypertension therapy

  2015cites this paper
• Polymorphisms in VEGFA gene affect the antihypertensive responses to enalapril

  2015cites this paper
• Obesity and renovascular disease.

  2015cites this paper
• Cerebral Cortical Microvascular Rarefaction in Metabolic Syndrome is Dependent on Insulin Resistance and Loss of Nitric Oxide Bioavailability

  2015cites this paper
• Modeling Perfusion Dynamics in the Skin During Iontophoresis of Vasoactive Drugs Using Single‐Pulse and Multiple‐Pulse Protocols

  2015cites this paper
• Effect of telmisartan on VEGF-induced and VEGF-independent angiogenic responsiveness of coronary endothelial cells in normal and streptozotocin (STZ)-induced diabetic rats

  2014cites this paper
• Distinct temporal phases of microvascular rarefaction in skeletal muscle of obese Zucker rats.

  2014cites this paper
• Obesity Is Associated with Lower Coronary Microvascular Density

  2013cites this paper
• Effects of ACE inhibition on endothelial progenitor cell mobilization and prognosis after acute myocardial infarction in type 2 diabetic patients

  2013cites this paper
• Hemopexin is up-regulated in plasma from type 1 diabetes mellitus patients: Role of glucose-induced ROS.

  2012cites this paper
• Perindopril protects against streptozotocin-induced hyperglycemic myocardial damage/alterations

  2012cites this paper
• Effects of Aerobic Exercise Training on Cardiac Renin-Angiotensin System in an Obese Zucker Rat Strain

  2012cites this paper
• Cardiovascular medications in angiogenesis—How to avoid the sting in the tail

  2012cites this paper
• The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy

  2011cites this paper
• Angiotensin type I receptor blockade in conjunction with enhanced Akt activation restores coronary collateral growth in the metabolic syndrome.

  2011cites this paper
• Therapeutic neovascularization for coronary disease: current state and future prospects

  2011cites this paper
• Vascular Consequences of Metabolic Syndrome Related Shifts in Cyclooxygenase Mediated Arachidonic Acid Metabolism

  2011cites this paper
• The Effects of G-CSF on Proliferation of Mouse Myocardial Microvascular Endothelial Cells

  2011cites this paper
• Ramipril modulates circadian gene expression in skeletal muscle

  2011cites this paper
• Assessment of Vascular Reactivity

  2010cites this paper
• Differential analyses of angiogenesis and expression of growth factors in micro- and macrovascular endothelial cells of type 2 diabetic rats.

  2009cites this paper
• Are Zucker obese rats a useful model for cardiovascular complications in metabolic syndrome? Physical, biochemical and oxidative stress considerations

  2009cites this paper
• Molecular mechanism of limbs' postischemic revascularization improved by perindopril in diabetic rats.

  2008cites this paper
• Functional and Partial Morphological Regression of Established Renal Injury in the Obese Zucker Rat by Blockade of the Renin-Angiotensin System

  2008cites this paper
• Obesity and vascular dysfunction.

  2008cites this paper
• Cardiac remodeling in obesity.

  2008cites this paper
• Increased vascular thromboxane generation impairs dilation of skeletal muscle arterioles of obese Zucker rats with reduced oxygen tension.

  2008cites this paper
• Changing Prevalence of Obesity and Link to Cardiovascular Disease

  2008cites this paper
• Effects of Antihypertensive Drugs on Capillary Rarefaction in Spontaneously Hypertensive Rats: Intravital Microscopy and Histologic Analysis

  2008cites this paper
• Obesity, Insulin Resistance, and Microvessel Density

  2007cites this paper
• Effects of anti-hypertensive drugs on vessel rarefaction.

  2007cites this paper
• Angiotensin I‐converting enzyme insertion‐related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma

  2007cites this paper
• Angiotensin-converting enzyme inhibition promotes coronary angiogenesis in the failing heart of Dahl salt-sensitive hypertensive rats.

  2007cites this paper
• The Mechanistic Basis for the Disparate Effects of Angiotensin II on Coronary Collateral Growth

  2007cites this paper
• Effects of perindopril in hypertensive patients with or without type 2 diabetes mellitus, and with altered insulin sensitivity

  2007cites this paper
• Interaction of Endothelial Nitric Oxide and Angiotensin in the Circulation

  2007cites this paper
• Vascular function in the metabolic syndrome and the effects on skeletal muscle perfusion: lessons from the obese Zucker rat.

  2006cites this paper
• The in vivo cardiac kinetics of Tc-99m N-NOET are accelerated in obese, hyperlipidemic Zucker rats

  2006cites this paper
• Coronary vascular dysfunction in obese type 2 diabetic mice.

  2006cites this paper
• Regulation of Vascular Endothelial Growth Factor Expression and Vascularization in the Myocardium by Insulin Receptor and PI3K/Akt Pathways in Insulin Resistance and Ischemia

  2006cites this paper
• Neointimal hyperplasia and vascular endothelial growth factor expression are increased in normoglycemic, insulin resistant, obese fatty rats.

  2006cites this paper
• Angiotensin I-converting enzyme ACE 2350*G and ACE-240*T-related genotypes and alleles are associated with higher susceptibility to endometriosis.

  2005cites this paper
• The impact of vascular risk factors on erectile function.

  2005cites this paper
• Antagonism of the renin-angiotensin system can counteract cardiac angiogenic vascular endothelial growth factor gene therapy and myocardial angiogenesis in the normal heart.

  2005cites this paper
• Hypertension‐Independent Microvascular Rarefaction in the Obese Zucker Rat Model of the Metabolic Syndrome

  2005cites this paper
• Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans.

  2005cites this paper
• Effects of nicotine and streptozotocin on the cardiovascular system

  2004cites this paper
• Nutrient Metabolism Calcium and Dairy Products Inhibit Weight and Fat Regain during Ad Libitum Consumption Following Energy Restriction in Ap 2-Agouti Transgenic Mice 1 , 2

  2004cites this paper
• Calcium and dairy products inhibit weight and fat regain during ad libitum consumption following energy restriction in Ap2-agouti transgenic mice.

  2004cites this paper