Effects of genistein and daidzein on the cell growth, cell cycle, and differentiation of human and murine melanoma cells(1).

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Nutritional Biochemistry

• Publication date

  2002-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0955-2863(02)00184-5PMID 12121829
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21waf/cip1, p27kip1, and Cdc25C expression11Abbreviations: PTK, protein tyrosine kinase; cdk, cyclin-dependent kinase; DMEM, Dulbecco’s Modified Eagle’s Medium; MTT

  2001cited by this paper
• Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression.

  2001cited by this paper
• p21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells.

  2000cited by this paper
• p53‐independent Induction of p21 (WAF1/CIP1), Reduction of Cyclin B1 and G2/M Arrest by the Isoflavone Genistein in Human Prostate Carcinoma Cells

  2000cited by this paper
• Increased induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats fed diets containing purified genistein or genistein-rich soya protein.

  2000cited by this paper
• Isoflavonoids and lignans have different potentials to modulate oxidative genetic damage in human colon cells.

  2000cited by this paper
• Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells.

  2000cited by this paper
• Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice.

  1999cited by this paper
• Dietary phytoestrogens in the prevention of long‐term postmenopausal diseases

  1999cited by this paper
• Effects of genistein and daidzein on membrane characteristics of HCT cells.

  1999cited by this paper
• Effects of isothiocyanates on growth and metastaticity of B16-F10 melanoma cells.

  1999cited by this paper
• Dietary phytoestrogens in the prevention of long-term postmenopausal diseases.

  1999cited by this paper
• Genistein inhibits proliferation similarly in estrogen receptor‐positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis

  1998cited by this paper
• Genistein induces p21(Cip1/WAF1) expression and blocks the G1 to S phase transition in mouse fibroblast and melanoma cells.

  1998cited by this paper
• Synergistic action of tiazofurin and genistein on growth inhibition and differentiation of K-562 human leukemic cells.

  1998cited by this paper
• Genistein exerts multiple suppressive effects on human breast carcinoma cells.

  1998cited by this paper
• Enhancement of immune function in mice fed high doses of soy daidzein.

  1997cited by this paper
• Inhibition of growth and induction of differentiation of metastatic melanoma cells in vitro by genistein: chemosensitivity is regulated by cellular p53.

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• Enhancement of experimental colon cancer by genistein.

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• Individual and combinatory effects of soy isoflavones on the in vitro potentiation of lymphocyte activation.

  1997cited by this paper
• Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the RAS signaling pathway

  1996cited by this paper
• Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis

  1995cited by this paper
• Soy intake and cancer risk: a review of the in vitro and in vivo data.

  1994cited by this paper
• Genistein arrests cell cycle progression at G2-M.

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• Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein.

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• Commonly occurring plant flavonoids have estrogenic activity.

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• Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression.

  1991cited by this paper
• Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II.

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• Genistein, a specific inhibitor of tyrosine-specific protein kinases.

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• Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.

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