Tight function zonula occludens-3 regulates cyclin D1–dependent cell proliferation

We show here that zonula occludens (ZO)-3 acts to sequester cyclin D1 at intercellular tight junctions. This study highlights an important new role for ZO family proteins in regulating epithelial cell proliferation through stabilization of cyclin D1 during mitosis.

• Publication year

  2011

• Venue

  Molecular Biology of the Cell

• Publication date

  2011-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E10-08-0677PMID 21411630PMCID 3093320
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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