Analysis and Manipulation of Aspartate Pathway Genes for l-Lysine Overproduction from Methanol by Bacillus methanolicus

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Applied and Environmental Microbiology

• Publication date

  2011-07-01

• Fields of study

  Biology, Chemistry, Engineering, Environmental Science, Medicine

• Identifiers
  DOI 10.1128/AEM.05093-11PMID 21724876PMCID PMC3165430
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Salt-Tolerant and Thermostable Glutaminases of Cryptococcus Species Form a New Glutaminase Family

  2011cited by this paper
• 3.47 – Lysine: Industrial Uses and Production

  2011cited by this paper
• Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for l-lysine production from methanol at 50°C

  2010influential reference
• Methanol-based industrial biotechnology: current status and future perspectives of methylotrophic bacteria.

  2009cited by this paper
• Disruption of metF Increased L-Lysine Production by Methylophilus methylotrophus from Methanol

  2008cited by this paper
• Metabolic regulation and overproduction of primary metabolites

  2008cited by this paper
• Overexpression of Wild-Type Aspartokinase Increases l-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus

  2008influential reference
• The IclR-Type Transcriptional Repressor LtbR Regulates the Expression of Leucine and Tryptophan Biosynthesis Genes in the Amino Acid Producer Corynebacterium glutamicum

  2007cited by this paper
• Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50°C

  2007cited by this paper
• Construction of Lactobacillus plantarum strain with enhanced L‐lysine yield

  2007cited by this paper
• Improving lysine production by Corynebacterium glutamicum through DNA microarray-based identification of novel target genes

  2007cited by this paper
• Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50 degrees C.

  2007cited by this paper
• L-lysine fermentation.

  2007cited by this paper
• Upregulated Transcription of Plasmid and Chromosomal Ribulose Monophosphate Pathway Genes Is Critical for Methanol Assimilation Rate and Methanol Tolerance in the Methylotrophic Bacterium Bacillus methanolicus

  2006cited by this paper
• L-Lysine biosynthetic pathway of Methylophilus methylotrophus and construction of an L-lysine producer.

  2006cited by this paper
• A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient l-lysine production

  2006cited by this paper
• Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus.

  2006cited by this paper
• Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum.

  2006cited by this paper
• Enhancement of L-lysine production in methylotroph Methylophilus methylotrophus by introducing a mutant LysE exporter.

  2006cited by this paper
• Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids.

  2006cited by this paper
• Characterization of the L-Lysine Biosynthetic Pathway in the Obligate Methylotroph Methylophilus methylotrophus

  2004cited by this paper
• Impact of 'ome' analyses on inverse metabolic engineering.

  2004cited by this paper
• Role of the Bacillus methanolicus Citrate Synthase II Gene, citY, in Regulating the Secretion of Glutamate in l-Lysine-Secreting Mutants

  2003cited by this paper
• Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch?

  2003cited by this paper
• The L box regulon: Lysine sensing by leader RNAs of bacterial lysine biosynthesis genes

  2003cited by this paper
• Biosynthesis of Amino Acids of the Glutamate and Aspartate Families, Alanine, and Polyamines

  2002cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutant

  2001cited by this paper
• Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.

  2001cited by this paper
• Elevated Intact Parathyroid Hormone Is Associated with Reduced Biochemical Markers of Bone Formation and Resorption Measured in Blood in Infant Piglets Receiving Oral Dexamethasone for 15 Days

  2001cited by this paper
• Overproduction of l-Lysine from Methanol by Methylobacillus glycogenes Derivatives Carrying a Plasmid with a Mutated dapA Gene

  2001cited by this paper
• Mutational analysis of the feedback sites of lysine-sensitive aspartokinase of Escherichia coli.

  1999cited by this paper
• The leader sequence of the Escherichia coli lysC gene is involved in the regulation of LysC synthesis.

  1998cited by this paper
• Improved L-lysine yield with Corynebacterium glutamicum: use of dapA resulting in increased flux combined with growth limitation

  1998cited by this paper
• Microbial Growth on C1 Compounds

  1996cited by this paper
• Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes.

  1996cited by this paper
• Production of L-Lysine and Some Other Amino Acids by Mutants of B. methanolicus

  1996cited by this paper
• Inverse metabolic engineering: a strategy for directed genetic engineering of useful phenotypes.

  1996cited by this paper
• Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants

  1995cited by this paper
• Cloning and nucleotide sequences of the homoserine dehydrogenase genes (hom) and the threonine synthase genes (thrC) of the gram-negative obligate methylotroph Methylobacillus glycogenes

  1994cited by this paper
• Cloning and sequence analysis of the meso-diaminopimelate decarboxylase gene from Bacillus methanolicus MGA3 and comparison to other decarboxylase genes

  1993cited by this paper
• Control of the Lysine Biosynthesis Sequence in Corynebacterium glutamicum as Analyzed by Overexpression of the Individual Corresponding Genes

  1991cited by this paper
• L-lysine production at 50 degrees C by mutants of a newly isolated and characterized methylotrophic Bacillus sp

  1990cited by this paper
• Desensitization of Bacillus subtilis aspartokinase I to allosteric inhibition by meso-diaminopimelate allows aspartokinase I to function in amino acid biosynthesis during exponential growth

  1990cited by this paper
• The effect of restriction on shotgun cloning and plasmid stability in Bacillus subtilis Marburg

  1987cited by this paper
• Genetic Analysis of Diaminopimelic Acid- and Lysine-Requiring Mutants of Escherichia coli

  1971cited by this paper
• Genetic Analysis of the Maltose A Region in Escherichia coli

  1969cited by this paper

• Development of a Novel Process Towards an l-Malate Biorefinery Using Methanol as Feedstock

  2024cites this paper
• Identification and Combinatorial Overexpression of Key Genes for Enhancing ε-Poly-L-lysine Biosynthesis in Streptomyces albulus

  2024cites this paper
• Giving a signal: How protein phosphorylation helps Bacillus navigate through different life stages.

  2023cites this paper
• Efficient cell factories for the production of N‐methylated amino acids and for methanol‐based amino acid production

  2022influential citation
• Discovery of Early-Branching Wolbachia Reveals Functional Enrichment on Horizontally Transferred Genes

  2022cites this paper
• Aerobic Utilization of Methanol for Microbial Growth and Production.

  2021cites this paper
• Developing a Riboswitch-Mediated Regulatory System for Metabolic Flux Control in Thermophilic Bacillus methanolicus

  2021cites this paper
• Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus

  2021cites this paper
• Chemical Production from Methanol Using Natural and Synthetic Methylotrophs

  2020cites this paper
• Progress in the metabolic engineering of bio-based lactams and their ω-amino acids precursors.

  2020cites this paper
• Identification of a cytosine methyltransferase that improves transformation efficiency in Methylomonas sp. DH-1

  2020cites this paper
• Host engineering for improved valerolactam production in Pseudomonas putida

  2019cites this paper
• Omics-driven identification and elimination of valerolactam catabolism in Pseudomonas putida KT2440 for increased product titer

  2019cites this paper
• Enzymatic characterization and molecular mechanism of a novel aspartokinase mutant M372I/T379W from Corynebacterium pekinense

  2019cites this paper
• Amino acid excretion from Euglena gracilis cells in dark and anaerobic conditions

  2019cites this paper
• Methanol as carbon substrate in the bio‐economy: Metabolic engineering of aerobic methylotrophic bacteria for production of value‐added chemicals

  2017cites this paper
• l-lysine production by Bacillus methanolicus: Genome-based mutational analysis and l-lysine secretion engineering.

  2017cites this paper
• Mutagenesis of Key Residues in the Binding Center of l‐Aspartate‐β‐Semialdehyde Dehydrogenase from Escherichia coli Enhances Utilization of the Cofactor NAD(H)

  2016cites this paper
• Finding approximate gene clusters with Gecko 3

  2016cites this paper
• Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains

  2015influential citation
• Metabolic engineering of Bacillus methanolicus and Corynebacterium glutamicum for the production of cadaverine from methanol

  2015cites this paper
• Methylotrophy in the thermophilic Bacillus methanolicus, basic insights and application for commodity production from methanol

  2014cites this paper
• Functional Characterization of Key Enzymes involved in l-Glutamate Synthesis and Degradation in the Thermotolerant and Methylotrophic Bacterium Bacillus methanolicus

  2013cites this paper
• Methylotrophic Bacillus methanolicus Encodes Two Chromosomal and One Plasmid Born NAD+ Dependent Methanol Dehydrogenase Paralogs with Different Catalytic and Biochemical Properties

  2013cites this paper
• Methanol oxidation by temperate soils and environmental determinants of associated methylotrophs

  2012cites this paper
• Genome Sequence of Thermotolerant Bacillus methanolicus: Features and Regulation Related to Methylotrophy and Production of l-Lysine and l-Glutamate from Methanol

  2012cites this paper
• Expression of recombinant green fluorescent protein in Bacillus methanolicus

  2012cites this paper
• Methanol fromProduction of l-Lysine and l-Glutamate Regulation Related to Methylotrophy and Bacillus methanolicus : Features and Genome Sequence of Thermotolerant

  2012cites this paper