Gap-junctional single-channel permeability for fluorescent tracers in mammalian cell cultures.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biophysical Journal

• Publication date

  2006-07-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1529/BIOPHYSJ.105.072306PMID 16632504PMCID PMC1483098
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2005influential reference
• The permeability of gap junction channels to probes of different size is dependent on connexin composition and permeant-pore affinities.

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• Selective permeability of gap junction channels.

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• A transient diffusion model yields unitary gap junctional permeabilities from images of cell-to-cell fluorescent dye transfer between Xenopus oocytes.

  2004influential reference
• Function of the voltage gate of gap junction channels: Selective exclusion of molecules

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• Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome

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• Conductance and Permeability of the Residual State of Connexin43 Gap Junction Channels

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• Cardiac Gap Junction Channels Show Quantitative Differences in Selectivity

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• Emerging issues of connexin channels: biophysics fills the gap

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• Three-dimensional structure of a recombinant gap junction membrane channel.

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  1997cited by this paper
• Monovalent Ion Selectivity Sequences of the Rat Connexin43 Gap Junction Channel

  1997cited by this paper
• Gap junction channels: new roles in disease.

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  1995cited by this paper
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• Dynamic gap junctional communication: a delimiting model for tissue responses.

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  1994cited by this paper
• Microelectrode techniques : the Plymouth Workshop handbook

  1994cited by this paper
• Exact solution of a model of diffusion in an infinite chain or monolayer of cells coupled by gap junctions.

  1990cited by this paper
• Relative roles of gap junction channels and cytoplasm in cell-to-cell diffusion of fluorescent tracers.

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• Gap junctional conductance and permeability are linearly related.

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• A model for the diffusion of fluorescent probes in the septate giant axon of earthworm. Axoplasmic diffusion and junctional membrane permeability.

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• Rates of diffusion of fluorescent molecules via cell-to-cell membrane channels in a developing tissue

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  1981cited by this paper
• Permeability of the cell-to-cell membrane channels in mammalian cell juncton.

  1979cited by this paper
• Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer.

  1978cited by this paper
• Size limit of molecules permeating the junctional membrane channels.

  1977cited by this paper

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