Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Mutation research

• Publication date

  1988-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0167-8817(88)90042-9PMID 3347205
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells

  1988cited by this paper
• Identification of nucleotide-excision-repair genes on human chromosomes 2 and 13 by functional complementation in hamster-human hybrids

  1987cited by this paper
• Biological and biochemical consequences of the human ERCC-1 repair gene after transfection into a repair-deficient CHO cell line.

  1987cited by this paper
• Differences between rodent and human cell lines in the amount of integrated DNA after transfection.

  1987cited by this paper
• Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.

  1986cited by this paper
• Recent Progress with the DNA Repair Mutants of Chinese Hamster Ovary Cells

  1986cited by this paper
• Assignment of a human DNA-repair gene associated with sister-chromatid exchange to chromosome 19.

  1986cited by this paper
• Correction of a nucleotide-excision-repair mutation by human chromosome 19 in hamster-human hybrid cells

  1985cited by this paper
• Genetic complementation of UV-induced DNA repair in Chinese hamster ovary cells by the denV gene of phage T4.

  1985cited by this paper
• Genetic complementation between UV-sensitive CHO mutants and xeroderma pigmentosum fibroblasts.

  1985cited by this paper
• Molecular cloning and chromosomal localization of DNA sequences associated with a human DNA repair gene

  1985cited by this paper
• Interspecies complementation analysis of xeroderma pigmentosum and UV-sensitive Chinese hamster cells.

  1985cited by this paper
• Microinjection of Micrococcus luteus UV-endonuclease restores UV-induced unscheduled DNA synthesis in cells of 9 xeroderma pigmentosum complementation groups.

  1985cited by this paper
• A ninth complementation group in xeroderma pigmentosum, XP I.

  1985cited by this paper
• Molecular cloning of a human DNA repair gene

  1984cited by this paper
• DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135

  1984cited by this paper
• Analysis of mammalian-cell mutagenesis and DNA repair using in-vitro selected CHO cell mutants

  1983cited by this paper
• Molecular identification of a human DNA repair gene following DNA-mediated gene transfer

  1983cited by this paper
• Isolation of Chinese hamster ovary cells with reduced unscheduled DNA synthesis after UV irradiation

  1982cited by this paper
• Repair capability and the cellular age response for killing and mutation induction after UV.

  1982cited by this paper
• The construction of cosmid libraries which can be used to transform eukaryotic cells.

  1982cited by this paper
• Hypersensitivity to mutation and sister-chromatid-exchange induction in CHO cell mutants defective in incising DNA containing UV lesions

  1982cited by this paper
• Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

  1981cited by this paper
• Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

  1981cited by this paper
• Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells.

  1980cited by this paper
• UV-light-induced mutations in synchronous CHO cells.

  1980cited by this paper
• Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

  1977cited by this paper
• A physical map of the DNA regions flanking the rabbit beta-globin gene.

  1977cited by this paper
• A physical map of the DNA regions flanking the rabbit β-globin gene

  1977cited by this paper
• Specific action of T4 endonuclease V on damaged DNA in xeroderma pigmentosum cells in vivo.

  1977cited by this paper
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.

  1975cited by this paper
• A new technique for the assay of infectivity of human adenovirus 5 DNA.

  1973cited by this paper
• Genetic heterogeneity of xeroderma pigmentosum demonstrated by somatic cell hybridization.

  1972cited by this paper

• First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure.

  2007cites this paper
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  2005cites this paper
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  2005cites this paper
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  2004cites this paper
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  2004cites this paper
• DNA repair in resistance to bifunctional alkylating and platinating agents.

  2002cites this paper
• Nucleotide excision repair gene (ERCC1) deficiency causes G2 arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21

  2000cites this paper
• Mechanism of cell cycle arrest in the ERCC1-deficient mouse model

  1999cites this paper
• Characterization and analysis of Chinese hamster ovary cell ERCC1 mutant alleles.

  1998cites this paper
• Plant homologue of human excision repair gene ERCC1 points to conservation of DNA repair mechanisms.

  1998cites this paper
• Transcription and mismatch repair in the mechanism of action of the anticancer drug cisplatin

  1997cites this paper
• ERCC1/ERCC4 5'-endonuclease activity as a determinant of hypoxic cell radiosensitivity.

  1996cites this paper
• DNA adducts of cis-diamminedichloroplatinum(II) and its trans isomer inhibit RNA polymerase II differentially in vivo.

  1995cites this paper
• Human DNA Repair Excision Nuclease

  1995cites this paper
• Comparison of common gene mutation tests in mammalian cells in culture: a position paper of the GUM Commission for the Development of Guidelines for Genotoxicity Testing.

  1994cites this paper
• Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.

  1993cites this paper
• Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics.

  1993cites this paper
• Expression of excision repair genes in non-malignant bone marrow from cancer patients.

  1993cites this paper
• Mouse chromosome 7.

  1992cites this paper
• UV-induced hprt mutations in a UV-sensitive hamster cell line from complementation group 3 are biased towards the transcribed strand.

  1992cites this paper
• Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

  1992cites this paper
• Increased resistance to the toxic effects of alkylating agents in tobacco expressing the E. coli DNA repair gene ada.

  1992cites this paper
• Requirement for ERCC-1 and ERCC-3 gene products in DNA excision repair in vitro. Complementation using rodent and human cell extracts.

  1992cites this paper
• Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines.

  1991cites this paper
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  1991cites this paper
• Identification of human genes involved in repair and tolerance of DNA damage

  1991cites this paper
• Cyclobutane-pyrimidine dimer excision in UV-sensitive CHO mutants and the effect of the human ERCC2 repair gene.

  1990cites this paper
• A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome.

  1990cites this paper
• Clues to the Organization of DNA Repair Systems Gained from Studies of Intragenomic Repair Heterogeneity

  1990cites this paper
• ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.

  1990cites this paper
• Molecular characterization of an Indian muntjac cell line deficient in aspects of DNA repair

  1990cites this paper
• Increased UV resistance in xeroderma pigmentosum group A cells after transformation with a human genomic DNA clone.

  1990cites this paper
• Molecular cloning and biological characterization of the human excision repair gene ERCC-3

  1990cites this paper
• Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.

  1989cites this paper
• Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening.

  1989cites this paper
• Molecular cloning and characterization of a mammalian excision repair gene that partially restores UV resistance to xeroderma pigmentosum complementation group D cells.

  1989cites this paper
• The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I.

  1989cites this paper
• Molecular Genetic Dissection of Mammalian Excision Repair

  1989cites this paper
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  1989cites this paper
• Human DNA Repair and Recombination Genes

  1989cites this paper
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  1989cites this paper
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  1989cites this paper
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  1988cites this paper
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  1988cites this paper
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  1988cites this paper