Local Interleukin-1beta in Pregnant Women with Bacterial Vaginosis and Adverse Pregnancy Outcomes

S. Cauci,J. Culhane

Published 2016 in Obstetrics & Gynecology International Journal

ABSTRACT

Objective: To assess if vaginal interleukin-(IL)-1beta in early pregnancy is associated with adverse outcome among BV-positive women. Study Design: 1,806 women were enrolled at 66th percentile) and lower (<33rd percentile) tertiles of IL-1beta concentrations were compared with the middle tertile (33rd to 66th percentile). Results: None of the IL-1beta tertiles was associated with increased risk for any adverse preterm outcome, nor preterm birth and miscarriage with or without exclusion of women with concurrent STDs. Conclusion: IL-1beta is not a risk marker for preterm birth among BV-positive women in early gestation.

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