Modulation of lamellipodial structure and dynamics by NO-dependent phosphorylation of VASP Ser239

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Cell Science

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1242/jcs.003061PMID 17684063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• AMP-activated Protein Kinase Impairs Endothelial Actin Cytoskeleton Assembly by Phosphorylating Vasodilator-stimulated Phosphoprotein*

  2007cited by this paper
• The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation

  2006cited by this paper
• NO-dependent osteoclast motility: reliance on cGMP-dependent protein kinase I and VASP

  2005cited by this paper
• Subsecond reorganization of the actin network in cell motility and chemotaxis.

  2005cited by this paper
• Ena/VASP Proteins Enhance Actin Polymerization in the Presence of Barbed End Capping Proteins*[boxs]

  2005influential reference
• STOP and GO with NO: Nitric oxide as a regulator of cell motility in simple brains

  2005cited by this paper
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  2004cited by this paper
• Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.

  2004cited by this paper
• Vasodilator-stimulated Phosphoprotein Activation of Serum-response Element-dependent Transcription Occurs Downstream of RhoA and Is Inhibited by cGMP-dependent Protein Kinase Phosphorylation*

  2004cited by this paper
• Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.

  2004cited by this paper
• Dynamic actin patterns and Arp2/3 assembly at the substrate-attached surface of motile cells.

  2004cited by this paper
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  2003cited by this paper
• How VASP enhances actin-based motility

  2003cited by this paper
• Nitric oxide and cyclic nucleotides are regulators of neuronal migration in an insect embryo

  2003cited by this paper
• Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility.

  2002cited by this paper
• Epithelial Inducible Nitric-oxide Synthase Is an Apical EBP50-binding Protein That Directs Vectorial Nitric Oxide Output*

  2002cited by this paper
• Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.

  2002cited by this paper
• Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration.

  2002cited by this paper
• Actin dynamics and cell-cell adhesion in epithelia.

  2001cited by this paper
• Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.

  2001cited by this paper
• The Vasodilator-Stimulated Phosphoprotein Is Regulated by Cyclic GMP-Dependent Protein Kinase During Neutrophil Spreading1

  2001cited by this paper
• Coexpressed nitric oxide synthase and apical beta(1) integrins influence tubule cell adhesion after cytokine-induced injury.

  2001cited by this paper
• Phosphorylation of the Vasodilator-stimulated Phosphoprotein Regulates Its Interaction with Actin*

  2000cited by this paper
• Rising behind NO: cGMP-dependent protein kinases.

  2000cited by this paper
• Vasodilator-Stimulated Phosphoprotein Serine 239 Phosphorylation as a Sensitive Monitor of Defective Nitric Oxide/cGMP Signaling and Endothelial Dysfunction

  2000cited by this paper
• Fyn-Binding Protein (Fyb)/Slp-76–Associated Protein (Slap), Ena/Vasodilator-Stimulated Phosphoprotein (Vasp) Proteins and the Arp2/3 Complex Link T Cell Receptor (Tcr) Signaling to the Actin Cytoskeleton

  2000cited by this paper
• Negative regulation of fibroblast motility by Ena/VASP proteins.

  2000influential reference
• cAMP-dependent Protein Kinase Phosphorylation of EVL, a Mena/VASP Relative, Regulates Its Interaction with Actin and SH3 Domains*

  2000cited by this paper
• The clutch hypothesis revisited: ascribing the roles of actin-associated proteins in filopodial protrusion in the nerve growth cone.

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• Regulation of Human Endothelial Cell Focal Adhesion Sites and Migration by cGMP-dependent Protein Kinase I*

  2000influential reference
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• The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation*

  1999cited by this paper
• VASP dynamics during lamellipodia protrusion

  1999cited by this paper
• Characterization of the actin binding properties of the vasodilator‐stimulated phosphoprotein VASP

  1999cited by this paper
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• Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis.

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• The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts.

  1992cited by this paper

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  2024cites this paper
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  2020cites this paper
• Differential Ser phosphorylation of vasodilator-stimulated phosphoprotein regulates colon tumor formation and growth.

  2020cites this paper
• Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling

  2019cites this paper
• The VASP–profilin1 (Pfn1) interaction is critical for efficient cell migration and is regulated by cell–substrate adhesion in a PKA-dependent manner

  2019cites this paper
• Alpha4‐overexpressing HL7702 cells can counteract microcystin‐LR effects on cytoskeletal structure

  2018cites this paper
• Protein phosphatase 2A inhibition and subsequent cytoskeleton reorganization contributes to cell migration caused by microcystin‐LR in human laryngeal epithelial cells (Hep‐2)

  2017cites this paper
• Extracellular superoxide dismutase is necessary to maintain renal blood flow during sepsis development

  2017cites this paper
• S-nitrosylation of VASP at cysteine 64 mediates the inflammation-stimulated increase in microvascular permeability.

  2017cites this paper
• Microcystin‐LR induces a wide variety of biochemical changes in the A549 human non‐small cell lung cancer cell line: Roles for protein phosphatase 2A and its substrates

  2017cites this paper
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• Nitric Oxide Modulates Postnatal Bone Marrow-Derived Mesenchymal Stem Cell Migration

  2016influential citation
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• Vasodilator-stimulated phosphoprotein restricts cell-to-cell spread of Shigella flexneri at the cell periphery.

  2015cites this paper
• New agents for thromboprotection

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• Serine phosphorylation of vasodilator-stimulated phosphoprotein (VASP) regulates colon cancer cell survival and apoptosis.

  2015cites this paper
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  2014cites this paper
• Homocysteine Disrupts Outgrowth of Microvascular Endothelium by an iNOS‐Dependent Mechanism

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