Ferulic acid reverses ABCB1-mediated paclitaxel resistance in MDR cell lines.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  European Journal of Pharmacology

• Publication date

  2016-09-05

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.ejphar.2016.05.023PMID 27262378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Campania Preventability Assessment Committee (Italy): A Focus on the Preventability of Non-steroidal Anti-inflammatory Drugs' Adverse Drug Reactions

  2017cited by this paper
• Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y

  2016cited by this paper
• South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy

  2016cited by this paper
• In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment

  2015cited by this paper
• Key factors which concur to the correct therapeutic evaluation of herbal products in free radical-induced diseases

  2015cited by this paper
• NSC23925 prevents the emergence of multidrug resistance in ovarian cancer in vitro and in vivo.

  2015cited by this paper
• Stabilizing versus Destabilizing the Microtubules: A Double-Edge Sword for an Effective Cancer Treatment Option?

  2015cited by this paper
• Ferulic acid: pharmacological and toxicological aspects.

  2014cited by this paper
• Effect of coumarin derivative-mediated inhibition of P-glycoprotein on oral bioavailability and therapeutic efficacy of paclitaxel.

  2014cited by this paper
• P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review

  2014cited by this paper
• Design and Synthesis of Human ABCB1 (P-Glycoprotein) Inhibitors by Peptide Coupling of Diverse Chemical Scaffolds on Carboxyl and Amino Termini of (S)-Valine-Derived Thiazole Amino Acid

  2014cited by this paper
• Combinatorial Measurement of CDKN1A/p21 and KIF20A Expression for Discrimination of DNA Damage-Induced Clastogenicity

  2014cited by this paper
• Bureau of Disease Prevention and Control, Ministry of Health, Beijing 100044, P. R. China

  2013cited by this paper
• Trans-ferulic acid-based solid lipid nanoparticles and their antioxidant effect in rat brain microsomes.

  2013cited by this paper
• BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo.

  2012cited by this paper
• Ferulic acid, a dietary phenolic acid, modulates radiation effects in Swiss albino mice.

  2012cited by this paper
• Antioxidants in cervical cancer: chemopreventive and chemotherapeutic effects of polyphenols.

  2012cited by this paper
• The role of breast cancer stem cells in metastasis and therapeutic implications.

  2011cited by this paper
• Chemosensitization of tumors by resveratrol

  2011cited by this paper
• Radiosensitizing effect of ferulic acid on human cervical carcinoma cells in vitro.

  2011cited by this paper
• Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters

  2011cited by this paper
• Multidrug resistance in cancer.

  2010cited by this paper
• Overcoming multidrug resistance in cancer: clinical studies of p-glycoprotein inhibitors.

  2010cited by this paper
• In vivo protective effect of ferulic acid against noise-induced hearing loss in the guinea-pig.

  2010cited by this paper
• Analysis of cycloheximide‐induced apoptosis in human leukocytes: Fluorescence microscopy using annexin V/propidium iodide versus acridin orange/ethidium bromide

  2006cited by this paper
• Impact of alkyl esters of caffeic and ferulic acids on tumor cell proliferation, cyclooxygenase enzyme, and lipid peroxidation.

  2006cited by this paper
• Clonogenic assay of cells in vitro

  2006cited by this paper
• Inhibitory effects of polyphenols on p-glycoprotein-mediated transport.

  2006cited by this paper
• Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.

  2006cited by this paper
• Resistance to paclitaxel is proportional to cellular total antioxidant capacity.

  2005cited by this paper
• Theoretical prediction of the relationship between phenol function and COX-2/AP-1 inhibition for ferulic acid-related compounds.

  2005cited by this paper
• Inhibition of P‐glycoprotein function by tea catechins in KB‐C2 cells

  2004cited by this paper
• Mechanisms of Taxol resistance related to microtubules

  2003cited by this paper
• Differential effects of cell cycle regulatory protein p21(WAF1/Cip1) on apoptosis and sensitivity to cancer chemotherapy.

  2003cited by this paper
• Multidrug resistance in cancer: role of ATP–dependent transporters

  2002cited by this paper
• Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells.

  2002cited by this paper
• The human ATP-binding cassette (ABC) transporter superfamily.

  2001cited by this paper
• Cell cycle-mediated drug resistance: an emerging concept in cancer therapy.

  2001cited by this paper
• Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides.

  2000cited by this paper
• Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells.

  2000cited by this paper
• Chemopreventive effects of ferulic acid on oral and rice germ on large bowel carcinogenesis.

  1999cited by this paper
• Quantitative structure-activity relationship of multidrug resistance reversal agents.

  1997cited by this paper
• Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay.

  1996cited by this paper
• Paclitaxel (taxol)

  1995cited by this paper
• LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions.

  1995cited by this paper
• Drug therapy : paclitaxel (Taxol)

  1995cited by this paper
• The core promoter region of the P-glycoprotein gene is sufficient to confer differential responsiveness to wild-type and mutant p53.

  1993cited by this paper
• Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification.

  1986cited by this paper
• Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

  1981cited by this paper
• A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants.

  1976cited by this paper

• The effects of low-dose X-ray pre-irradiation followed by 4-hydroxybenzoic acid and vanillic acid on P-glycoprotein-mediated efflux pirarubicin in multidrug-resistant K562/Dox cells.

  2026cites this paper
• Intestinal Permeation Characteristics via Non-Everted Gut Sac of Diterpene Lactones from Pure Andrographolide and Three Different Andrographis Extracts: An Investigation into Liqui-Mass with Different Solvents

  2026cites this paper
• 3D printed GelMA/HAMA based mechanical microenvironment boosted PDAC chemoresistance via NRF2-repressed ferroptosis.

  2025cites this paper
• Efficacy and mechanisms of Angelica sinensis in treating endometrial cancer: an integrated study

  2025cites this paper
• Much More than Nutrients: The Protective Effects of Nutraceuticals on the Blood–Brain Barrier in Diseases

  2025cites this paper
• Potential Alteration of Rifampicin's Bioavailability by Phyllanthus niruri Supplementation in Tuberculosis Therapy.

  2025cites this paper
• Ferulic acid inhibiting colon cancer cells at different Duke’s stages

  2025cites this paper
• Research Progress in the Medicine-Food Dual Use of Angelica sinensis in Digestive System Tumors

  2025cites this paper
• Quercetin and Its Metabolites: Mechanistic Insights as the Basis of Their Therapeutic Potential in NAFLD and HCC

  2025cites this paper
• Algerian Propolis from Distinct Geographical Locations: Chemical Profiles, Antioxidant Capacity, Cytotoxicity and Inhibition of 5‐Lipoxygenase Product Biosynthesis

  2024cites this paper
• In Vitro Anticancer Effects of Aqueous Leaf Extract from Nepeta nuda L. ssp. nuda

  2024cites this paper
• Metabolomics and network pharmacology reveal partial insights into the hypolipidemic mechanisms of ferulic acid in a dyslipidemia mouse model

  2024cites this paper
• Corn Husk Ferulic Acid Induces Apoptosis of Breast Cancer Cells via ROS‐Mediated Signaling Pathways

  2024cites this paper
• Molecular Evidence of the Bio-activities of Traditional Home Medicine Ingredients.

  2024cites this paper
• Morin reverses P‐glycoprotein‐mediated multidrug‐resistance in KBChR‐8‐5 cancer cell lines

  2024cites this paper
• Andrographolide reverts multidrug resistance in KBChR 8‐5 cells through AKT signaling pathway

  2024cites this paper
• The Use of an Antioxidant Enables Accurate Evaluation of the Interaction of Curcumin on Organic Anion-Transporting Polypeptides 4C1 by Preventing Auto-Oxidation

  2024cites this paper
• Chemosensitizing potential of andrographolide in P-glycoprotein overexpressing multidrug-resistant cancer cell lines

  2023cites this paper
• POTENTIAL HERB-DRUG INTERACTION OF DECALEPIS HAMILTONII VIA P-GP MEDIATED PHARMACOKINETIC INTERACTION WITH FEXOFENADINE IN RATS: AN IN SITU AND IN VIVO STUDY

  2023cites this paper
• Resveratrol as sensitizer in colorectal cancer plasticity

  2023cites this paper
• Molecular mechanism of ferulic acid and its derivatives in tumor progression

  2023cites this paper
• Enhanced delivery of quercetin and doxorubicin using β-cyclodextrin polymer to overcome P-glycoprotein mediated multidrug resistance.

  2023cites this paper
• Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review

  2022cites this paper
• Computational Modeling on Binding Interactions of Cyclodextrins with the Human Multidrug Resistance P-glycoprotein Toward Efficient Drug-Delivery System Applications.

  2022cites this paper
• Sesamol Augments Paclitaxel-Induced Apoptosis in Human Cervical Cancer Cell Lines

  2022cites this paper
• Modulation of p-glycoprotein-mediated efflux pirarubicin in living multidrug-resistant K562/Dox cell lines by 4-hydroxybenzoic acid and 4-hydroxy-3-methoxybenzoic acid via impairment of the cellular energetic state

  2022cites this paper
• Advances in Dietary Phenolic Compounds to Improve Chemosensitivity of Anticancer Drugs

  2022cites this paper
• Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review

  2022cites this paper
• Potentiation of Cell Death and DNA damage through 5-Fluorouracil and Ferulic acid Coadministration in p53 Mutant HT-29 Cell Lines

  2022cites this paper
• Supramolecular self-assembly and perfected in vitro/vivo property of 5-fluorouracil and ferulic acid on the strength of double optimized strategy: the first 5-fluorouracial-phenolic acid nutraceutical cocrystal with synergistic antitumor efficacy.

  2021cites this paper
• Nobiletin Enhances the Chemotherapeutic Efficacy of Docetaxel through Inhibition of Phosphatidylinositol 3-Kinase/Protein Kinase B and Induction of Apoptosis in Colon Cancer Cells

  2021cites this paper
• Therapeutic strategies to overcome taxane resistance in cancer.

  2021cites this paper
• Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction

  2021cites this paper
• Artichoke Polyphenols Sensitize Human Breast Cancer Cells to Chemotherapeutic Drugs via a ROS-Mediated Downregulation of Flap Endonuclease 1

  2020cites this paper
• PAMAM G4.5 dendrimers for targeted delivery of ferulic acid and paclitaxel to overcome P‐glycoprotein‐mediated multidrug resistance

  2020cites this paper
• Cytotoxic and Apoptotic Effects of Ferulic Acid on Renal Carcinoma Cell Line (ACHN)

  2020cites this paper
• Ferulic acid reverses P-glycoprotein-mediated multidrug resistance via inhibition of PI3K/Akt/NF-κB signaling pathway.

  2019cites this paper
• Pharmacokinetic Alteration of Paclitaxel by Ferulic Acid Derivative

  2019influential citation
• A New Ferulic Acid-Nicotinamide Cocrystal With Improved Solubility and Dissolution Performance.

  2019cites this paper
• Folate–Gold–Bilirubin Nanoconjugate Induces Apoptotic Death in Multidrug-Resistant Oral Carcinoma Cells

  2019cites this paper
• Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction

  2018cites this paper
• How to make P-glycoprotein (ABCB1, MDR1) harbor mutations and measure its expression and activity in cell cultures?

  2018cites this paper
• Anthocyanins and their gut metabolites attenuate monocyte adhesion and transendothelial migration through nutrigenomic mechanisms regulating endothelial cell permeability

  2018cites this paper
• Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays.

  2018cites this paper
• Retraction Note: Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines

  2018cites this paper
• Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines

  2018cites this paper
• A novel serum-stable liver targeted cytotoxic system using valerate-conjugated chitosan nanoparticles surface decorated with glycyrrhizin.

  2017cites this paper
• Drug resistance reversal in ovarian cancer cells of paclitaxel and borneol combination therapy mediated by PEG-PAMAM nanoparticles

  2017cites this paper
• Chemical characterization and cytotoxic activity evaluation of Lebanese propolis.

  2017cites this paper
• RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel.

  2017cites this paper
• Alzheimer's and Parkinson's Disease Novel Therapeutic Target: The Mitochondrial Pyruvate Carrier - Ligand Docking to Screen Natural Compounds Related to Classic Inhibitors

  2017cites this paper
• New insights into the ameliorative effects of ferulic acid in pathophysiological conditions.

  2017cites this paper
• Assessing the anticancer effects associated with food products and/or nutraceuticals using in vitro and in vivo preclinical development-related pharmacological tests.

  2017cites this paper
• Ferulic acid in Lolium multiflorum inhibits adipogenesis in 3T3-L1 cells and reduced high-fat-diet-induced obesity in Swiss albino mice via regulating p38MAPK and p44/42 signal pathways

  2017cites this paper
• Ferulic acid relaxed rat aortic, small mesenteric and coronary arteries by blocking voltage‐gated calcium channel and calcium desensitization via dephosphorylation of ERK1/2 and MYPT1

  2017cites this paper
• MicroRNA-595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1

  2016cites this paper
• Retro-Curcuminoids as Mimics of Dehydrozingerone and Curcumin: Synthesis, NMR, X-ray, and Cytotoxic Activity

  2016influential citation
• Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible

  year unknowncites this paper