Medical management of langerhans cell histiocytosis from diagnosis to treatment

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Expert Opinion on Pharmacotherapy

• Publication date

  2012-05-21

• Fields of study

  Medicine

• Identifiers
  DOI 10.1517/14656566.2012.688028PMID 22578036
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pulmonary Langerhans cell histiocytosis

  2013cited by this paper
• Pulmonary involvement in pediatric-onset multisystem Langerhans cell histiocytosis: effect on course and outcome.

  2012cited by this paper
• Serial computed tomography and lung function testing in pulmonary Langerhans’ cell histiocytosis

  2012cited by this paper
• Efficacy of vinblastine in central nervous system Langerhans cell histiocytosis: a nationwide retrospective study

  2011influential reference
• Fifteen years of treatment with intravenous immunoglobulin in central nervous system Langerhans cell histiocytosis

  2011cited by this paper
• Langerhans cell histiocytosis with refractory central nervous system involvement responsive to infliximab

  2011cited by this paper
• Central diabetes insipidus as the inaugural manifestation of Langerhans cell histiocytosis: natural history and medical evaluation of 26 children and adolescents.

  2011cited by this paper
• Neurodegenerative central nervous system Langerhans cell histiocytosis and coincident hydrocephalus treated with vincristine/cytosine arabinoside

  2010cited by this paper
• Inhibition of mutated, activated BRAF in metastatic melanoma.

  2010cited by this paper
• Selectively targeting mutant BRAF in thyroid cancer.

  2010cited by this paper
• Central nervous system disease in Langerhans cell histiocytosis.

  2010cited by this paper
• Recurrent BRAF mutations in Langerhans cell histiocytosis.

  2010cited by this paper
• Comparison of FDG‐PET scans to conventional radiography and bone scans in management of Langerhans cell histiocytosis

  2009cited by this paper
• Cholesteatoma Secondary to Temporal Bone Involvement by Langerhans Cell Histiocytosis: A Complication Amenable to Curative Surgery

  2009cited by this paper
• Intradural dirofilariasis mimicking a Langerhans cell histiocytosis tumor

  2009cited by this paper
• 2′‐chlorodeoxyadenosine (2‐CdA) as salvage therapy for Langerhans cell histiocytosis (LCH). results of the LCH‐S‐98 protocol of the histiocyte society

  2009cited by this paper
• Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification.

  2008influential reference
• Immunohistochemical Expression of Langerin in Langerhans Cell Histiocytosis and Non-Langerhans Cell Histiocytic Disorders

  2008cited by this paper
• Neurodegenerative central nervous system disease as late sequelae of Langerhans cell histiocytosis. Report from the Japan LCH Study Group

  2008cited by this paper
• Reactivations in multisystem Langerhans cell histiocytosis: data of the international LCH registry.

  2008cited by this paper
• Correlation between High-Resolution Computed Tomography Findings and Lung Function in Pulmonary Langerhans Cell Histiocytosis

  2007cited by this paper
• MRI features of neurodegenerative Langerhans cell histiocytosis

  2006cited by this paper
• Risk factors for diabetes insipidus in langerhans cell histiocytosis

  2006influential reference
• BRAF and NRAS mutations in melanoma and melanocytic nevi

  2006cited by this paper
• Whole-body MRI of Langerhans cell histiocytosis: comparison with radiography and bone scintigraphy

  2006influential reference
• Improved outcome in the treatment of pediatric multifocal Langerhans cell histiocytosis

  2006influential reference
• Long term morbidity and health related quality of life after multi-system Langerhans cell histiocytosis.

  2006cited by this paper
• Long-term follow-up of Langerhans cell histiocytosis: 39 years' experience at a single centre.

  2005cited by this paper
• Multi-centre pilot study of 2-chlorodeoxyadenosine and cytosine arabinoside combined chemotherapy in refractory Langerhans cell histiocytosis with haematological dysfunction.

  2005cited by this paper
• Histiocytic disorders of children and adults

  2005cited by this paper
• Improved outcome of treatment-resistant high-risk Langerhans cell histiocytosis after allogeneic stem cell transplantation with reduced-intensity conditioning

  2005cited by this paper
• Endocrine involvement in pediatric-onset Langerhans' cell histiocytosis: a population-based study.

  2004influential reference
• MR imaging presentation of intracranial disease associated with Langerhans cell histiocytosis.

  2004cited by this paper
• BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment

  2004cited by this paper
• Retinoic acid therapy in “degenerative‐like” neuro‐langerhans cell histiocytosis: A prospective pilot study

  2004cited by this paper
• Outcome in children with pulmonary Langerhans cell histiocytosis

  2004cited by this paper
• Langerin (CD207) Staining in Normal Pediatric Tissues, Reactive Lymph Nodes, and Childhood Histiocytic Disorders

  2004cited by this paper
• Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment.

  2004cited by this paper
• A New clinical score for disease activity in Langerhans cell histiocytosis

  2004influential reference
• Permanent consequences in Langerhans cell histiocytosis patients: A pilot study from the Histiocyte Society—Late Effects Study Group

  2004influential reference
• Diabetes insipidus and Langerhans cell histiocytosis: a case report of reversibility with 2-chlorodeoxyadenosine.

  2003cited by this paper
• Langerhans cell histiocytosis in adults. Report from the International Registry of the Histiocyte Society.

  2003cited by this paper
• Response to initial treatment of multisystem Langerhans cell histiocytosis: an important prognostic indicator.

  2002cited by this paper
• Macrophage Activation and Hemophagocytic Syndrome in Langerhans Cell Histiocytosis: Report of 30 Cases

  2002cited by this paper
• Accumulation of Immature Langerhans Cells in Human Lymph Nodes Draining Chronically Inflamed Skin

  2002cited by this paper
• Mutations of the BRAF gene in human cancer

  2002cited by this paper
• A randomized trial of treatment for multisystem Langerhans' cell histiocytosis.

  2001influential reference
• Pulmonary Langerhans'-cell histiocytosis.

  2000cited by this paper
• Central diabetes insipidus in children and young adults.

  2000cited by this paper
• Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.

  2000cited by this paper
• Treatment of Multisystem Langerhans Cell Histiocytosis. Results of the DAL-HX 83 and DAL-HX 90 Studies

  2000cited by this paper
• Treatment of multisystem Langerhans cell histiocytosis. Results of the DAL-HX 83 and DAL-HX 90 studies. DAL-HX Study Group.

  2000cited by this paper
• Adult pulmonary Langerhans' cell histiocytosis

  2000cited by this paper
• Langerhans Cell Histiocytosis and the Central Nervous System in Childhood: Evolution and Prognostic Factors. Results of a Collaborative Study

  2000cited by this paper
• Use of indomethacin in Langerhans cell histiocytosis.

  1999cited by this paper
• Langerhans cell histiocytosis in adults.

  1998cited by this paper
• International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology.

  1997cited by this paper
• Langerhans'-cell histiocytosis in adults.

  1997cited by this paper
• Diabetes insipidus associated with Langerhans cell histiocytosis: is it reversible?

  1997cited by this paper
• Bone scintigraphy evaluated in diagnosing and staging Langerhans' cell histiocytosis and related disorders.

  1996cited by this paper
• A multicentre retrospective survey of Langerhans' cell histiocytosis: 348 cases observed between 1983 and 1993. The French Langerhans' Cell Histiocytosis Study Group.

  1996cited by this paper
• Cutaneous Histiocytosis with Langerhans Cell eatures Induced by Scabies: A Case Report

  1994cited by this paper
• Central nervous system disease in Langerhans cell histiocytosis.

  1994cited by this paper
• Treatment strategy for disseminated langerhans cell histiocytosis

  1994cited by this paper
• Treatment strategy for disseminated Langerhans cell histiocytosis. DAL HX-83 Study Group.

  1994cited by this paper
• Otitis externa in Langerhans' cell histiocytosis--the successful use of topical nitrogen mustard.

  1994cited by this paper
• Intralesional Infiltration of Corticosteroids in Localized Langerhans' Cell Histiocytosis

  1992cited by this paper
• Topical nitrogen mustard: an effective treatment for cutaneous Langerhans cell histiocytosis.

  1991cited by this paper
• Healing rates of treated and untreated bone lesions in histiocytosis X.

  1985cited by this paper
• Histiocytosis X: rate and pattern of resolution of osseous lesions.

  1984cited by this paper

• Unveiling Langerhans cell histiocytosis: A rare cause of scalp lesions in pediatrics

  2025cites this paper
• Langerhans cell histiocytosis of the jaw: clinical analysis of 68 cases

  2025cites this paper
• Isolated Langerhans cell histiocytosis of the stomach in adults: An analysis of clinicopathologic characteristics and molecular genetics

  2024cites this paper
• Molecular Mutations in Histiocytosis: A Comprehensive Survey of Genetic Alterations

  2024cites this paper
• Adult-onset Langerhans cell histiocytosis – A Trojan horse of oral cavity: A case report with rare clinical presentation

  2023cites this paper
• Langerhans Cell Histiocytosis in Children: Literature Review

  2023cites this paper
• Modern approaches to the treatment of relapses and refractory forms of Langerhans cell histiocytosis. Literature review

  2023cites this paper
• Multifocal Langerhans' Cell Histiocytosis in an Adult

  2023cites this paper
• Pediatric pulmonary multisystem langerhans cell histiocytosis: does lung lesion severity affect the outcome?

  2023cites this paper
• Thyroid Langerhans cell histiocytosis concurrent with papillary thyroid carcinoma: A case report and literature review

  2023cites this paper
• Resolution and Re-ossification of Orbital-Wall Langerhans Cell Histiocytosis Following Stereotactic Needle Biopsy

  2022cites this paper
• Recurrent eosinophilic granuloma of the maxilla in an adult female: About a rare case report

  2022cites this paper
• Liver transplantation in a child with liver cirrhosis caused by langerhans cell histiocytosis: a case report

  2022cites this paper
• Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis

  2022cites this paper
• Secondary Acquired Cholesteatoma in Langerhans Cell Histiocytosis Patient

  2022cites this paper
• Gastrointestinal Langerhans cell histiocytosis with unifocal, single‐system involvement in adults: Cases report and literature review

  2022cites this paper
• Langerhans cell histiocytosis. Advances in pathogenesis and clinical practice.

  2022cites this paper
• Histiocitosis de células de Langerhans. Avances en la patogenia y práctica clínica

  2022cites this paper
• Integrated imaging of systemic Langerhans cell histiocytosis in an infant

  2022cites this paper
• An Extremely Rare Cause of an Obstructive Jaundice in Adults: Limited Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct

  2022cites this paper
• Langerhan’s cell histiocytosis with oral manifestation in a 3-year-old child: a case report

  2021cites this paper
• Histiocytosis and the nervous system: from diagnosis to targeted therapies

  2021cites this paper
• High prevalence of BRAFV600E in patients with cholestasis, sclerosing cholangitis or liver fibrosis secondary to Langerhans cell histiocytosis

  2021cites this paper
• Imagerie de l’histiocytose langerhansienne chez l’enfant

  2021cites this paper
• Case Report: Multisystem Langerhans Cell Histiocytosis (LCH) and Myelodysplastic Syndrome (MDS) in a 13-Month-Old Female

  2021cites this paper
• BRAFV600E Mutation in Cell-Free DNA, Rather than in Lesion Tissues, at Diagnosis Is An Independent Prognostic Factor in Children with Langerhans Cell Histiocytosis

  2021cites this paper
• Langerhans Cell Histiocytosis and Diabetes Insipidus

  2021cites this paper
• Langerhans Cell Histiocytosis (LCH)

  2021cites this paper
• Langerhans Hücreli Histiositozis Olgularında Flor-18 Florodeoksiglukoz PET/BT’nin Rolü

  2020influential citation
• Congenital Unilesional Cutaneous Langerhans Cell Histiocytosis: A Case Report.

  2020cites this paper
• A mutation in POLR3E impairs antiviral immune response and RNA polymerase III

  2020cites this paper
• Pediatric langerhans cell histiocytosis of the temporal bone: A rare case report and review of literature

  2020cites this paper
• Long‐term efficacy and safety of 2CdA (cladribine) in extra‐pulmonary adult‐onset Langerhans cell histiocytosis: analysis of 23 cases from the French Histiocytosis Group and systematic literature review

  2020cites this paper
• Langerhans cell histiocytosis of the thyroid together with papillary thyroid carcinoma

  2020cites this paper
• Childhood Langerhans cell histiocytosis: a disease with many faces

  2019cites this paper
• Histiocytic Neoplasma

  2019cites this paper
• Outcome of High-risk Langerhans Cell Histiocytosis (LCH) in Egyptian Children, Does Intermediate-dose Methotrexate Improve the Outcome?

  2019cites this paper
• [Langerhans cell histiocytosis revealed by a temporomandibular joint disorder: Report of a case and review of the craniofacial expressions].

  2019cites this paper
• Histiocytose langerhansienne révélée par un désordre de l’appareil manducateur : rapport d’un cas et revue de la littérature des atteintes crâniofaciales

  2019cites this paper
• MESTRADO INTEGRADO EM MEDICINA – TRABALHO FINAL

  2019cites this paper
• Steroid Induced Cataract in Langerhans Cell Histiocytosis Patient

  2019cites this paper
• Childhood pulmonary Langerhans cell histiocytosis: a comprehensive clinical-histopathological and BRAFV600E mutation study from the French national cohort.

  2019cites this paper
• Primary Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct Occurring in an Adult Patient

  2018cites this paper
• First-Line Treatment of Pediatric Langerhans Cell Histiocytosis

  2018cites this paper
• A 17-month-old girl presented with jaundice, hepatosplenomegaly, ascites and scaly erythematous skin lesion

  2018cites this paper
• Histiocitose das células de Langerhans no sistema nervoso central: relato de caso incomum

  2018cites this paper
• Ninety-year-old man with hypereosinophilia, lymphadenopathies and pruritus

  2018cites this paper
• An update on the treatment of pediatric-onset Langerhans cell histiocytosis through pharmacotherapy

  2018cites this paper
• Langerhans cell histiocytosis in children – a disease with many faces. Recent advances in pathogenesis, diagnostic examinations and treatment

  2018influential citation
• Étude rétrospective des effets indésirables cutanés du vemurafenib dans une cohorte européenne d’enfants traités pour histiocytose langerhansienne réfractaire

  2018influential citation
• Otic Langerhans Cell Histiocytosis in Adults: A Report of Two Cases

  2018cites this paper
• Multisystemic Langerhans cell histiocytosis in an adult

  2017influential citation
• Histiocytoses: emerging neoplasia behind inflammation.

  2017cites this paper
• Histiocytose langerhansienne de l’enfant

  2017cites this paper
• Quand une histiocytose langerhansienne passe pour une atteinte extradigestive de la rectocolite hémorragique : à propos d’un cas

  2017cites this paper
• [Child Langerhans cell histiocytosis].

  2017cites this paper
• Langerhans Cell Histiocytosis Mimicking Periapical Pathology in a 39-year-old Man.

  2017cites this paper
• BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.

  2016cites this paper
• An unusual case of an anterior mediastinal mass in a child with cystic lung disease

  2016cites this paper
• Spontaneous remission of eosinophilic granuloma of the maxilla after incisional biopsy: a case report

  2016cites this paper
• Langerhans cell histiocytosis: therapeutic strategy and outcome in a 30‐year nationwide cohort of 1478 patients under 18 years of age

  2016cites this paper
• Two Unusual Cases of Human Immunodeficiency Virus-Negative Patients with Talaromyces marneffei Infection.

  2016cites this paper
• A case of Langerhans cell histiocytosis mimicking child abuse.

  2016cites this paper
• Thyroid Langerhans cell histiocytosis and papillary thyroid carcinoma.

  2016cites this paper
• Langerhans Cell Histiocytosis (LCH) in Egyptian Children: Does Reactivation Affect the Outcome?

  2016cites this paper
• Conjunctival langerhans cell histiocytosis: a case report.

  2015cites this paper
• [Langerhans cell histiocytosis in adults].

  2015cites this paper
• Management and Outcome of Patients With Langerhans Cell Histiocytosis and Single‐Bone CNS‐Risk Lesions: A Multi‐Institutional Retrospective Study

  2015influential citation
• Cutaneous langerhans cell histiocytosis : A diagnostic challenge , two case reports and review of literature

  2015cites this paper
• Langerhans Cell Histiocytosis Presenting as Endocrine Disorders in an Adult Patient: A Case Report

  2015cites this paper
• Langerhans cell histiocytosis: Differences and similarities in long-term outcome of paediatric and adult patients at a single institutional centre

  2015cites this paper
• istiocytose langerhansienne de l ’ adulte angerhans cell histiocytosis in adults

  2015cites this paper
• Rhabdomyosarcoma and other pediatric temporal bone malignancies.

  2015cites this paper
• Langerhans Cell Histiocytosis in an Adult - a rare, life-threatening and not to be missed.

  2014cites this paper
• Narrowband Ultraviolet B Light in Langerhans Cell Histiocytosis: A Case Report

  2014cites this paper
• Involvement of occipital bone in langerhans cell histiocytosis: A case report

  2014cites this paper
• A Case of Langerhans Cell Histiocytosis With Risk Organ Involvement in a Young Adult

  2014cites this paper
• Heparanase expression in Langerhans cell histiocytosis

  2014cites this paper
• Langerhans cell histiocytosis in IPEX syndrome: Possible role for natural regulatory T cells?

  2014cites this paper
• Solitary Langerhans cell histiocytosis of frontal lobe: a case report and literature review.

  2014cites this paper
• Activating BRAF V600E Mutation in Aggressive Pediatric Langerhans Cell Histiocytosis: Demonstration by Allele-specific PCR/Direct Sequencing and Immunohistochemistry

  2014cites this paper
• Langerhans cell histiocytosis of the urinary bladder in a patient with bladder cancer previously treated with intravesical Bacillus Calmette-Guérin therapy.

  2014cites this paper
• Swelling of bilateral parotid glands: An unusual symptom of multisystem Langerhans cell histiocytosis

  2014cites this paper
• Cladribine improves lung cysts and pulmonary function in a child with histiocytosis

  2014cites this paper
• Oksipital kemik yerleşimli langerhans hücreli histiyositozis: Olgu sunumu Involvement of occipital bone in langerhans cell histiocytosis: A case report

  2014cites this paper
• Clonally Related Follicular Lymphomas and Langerhans Cell Neoplasms: Expanding the Spectrum of Transdifferentiation

  2013cites this paper
• A tale of two histiocytic disorders.

  2013cites this paper
• Langerhans Cell Sarcoma in Two Young Children: Imaging Findings on Initial Presentation and Recurrence

  2013influential citation
• Histiocytose agressive à cellules de Langerhans 20 ans après un cancer du sein : à propos d’un cas

  2013cites this paper
• Chronic right-sided otorrhea. Langerhans cell histiocytosis (LCH).

  2013cites this paper
• Soft tissue Langerhans cell histiocytosis with secondary bone involvement in extremities: evolution of lesions in two patients

  2013cites this paper
• Langerhans Cell Histiocytosis of the Orbit

  2013cites this paper
• Histiocytose langerhansienne : place actuelle de l’imagerie☆

  2013cites this paper
• Otic Langerhans' Cell Histiocytosis in an Adult: A Case Report and Review of the Literature

  2013cites this paper
• Langerhans cell histiocytosis: pragmatic empirism on the road to rational cure

  2012influential citation
• Oral manifestations of chronic disseminated langerhans cell histiocytosis: a case report

  2012cites this paper
• [Langerhans cell histiocytosis].

  2010cites this paper
• Sage Open Medical Case Reports

  year unknowncites this paper