Human neural progenitor cells decrease photoreceptor degeneration, normalize opsin distribution and support synapse structure in cultured porcine retina.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Brain Research

• Publication date

  2016-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.brainres.2016.06.039PMID 27369448
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells

  2016cited by this paper
• Glia-neuron interactions in the mammalian retina.

  2016cited by this paper
• Stem cells in clinical trials for treatment of retinal degeneration

  2016cited by this paper
• Platelet-Derived Growth Factor Preserves Retinal Synapses in a Rat Model of Ocular Hypertension.

  2016cited by this paper
• Extent of Detached Retina and Lens Status Influence Intravitreal Protein Expression in Rhegmatogenous Retinal Detachment.

  2015cited by this paper
• Müller glia as an important source of cytokines and inflammatory factors present in the gliotic retina during proliferative vitreoretinopathy

  2015cited by this paper
• Cellular strategies for retinal repair by photoreceptor replacement.

  2015cited by this paper
• Early Events of Synapse Disassembly in the Damaged Retina

  2015cited by this paper
• Synaptic remodeling of neuronal circuits in early retinal degeneration

  2015cited by this paper
• Müller Glia Activation in Response to Inherited Retinal Degeneration Is Highly Varied and Disease-Specific

  2015cited by this paper
• Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer.

  2015cited by this paper
• Human iPSC‐Derived Neural Progenitors Preserve Vision in an AMD‐Like Model

  2015cited by this paper
• RPE necroptosis in response to oxidative stress and in AMD.

  2015cited by this paper
• Feet on the ground: Physical support of the inner retina is a strong determinant for cell survival and structural preservation in vitro.

  2014cited by this paper
• An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina

  2014cited by this paper
• Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases.

  2014cited by this paper
• A Novel In Vivo Model of Focal Light Emitting Diode-Induced Cone-Photoreceptor Phototoxicity: Neuroprotection Afforded by Brimonidine, BDNF, PEDF or bFGF

  2014cited by this paper
• Photoreceptor degeneration, structural remodeling and glial activation: a morphological study on a genetic mouse model for pericyte deficiency.

  2014cited by this paper
• Autophagy and ER-stress contribute to photoreceptor degeneration in cultured adult porcine retina.

  2014cited by this paper
• Photoreceptor cell death and rescue in retinal detachment and degenerations.

  2013cited by this paper
• Early degeneration of photoreceptor synapse in Ccl2/Cx3cr1‐deficient mice on Crb1rd8 background

  2013cited by this paper
• Effects of Glial Cell Line-derived Neurotrophic Factor on the Cultured Adult Full-thickness Porcine Retina

  2013cited by this paper
• CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells

  2013cited by this paper
• Neural Stem Cells Derived by Small Molecules Preserve Vision.

  2013cited by this paper
• Role of endoplasmic reticulum stress in light‐induced photoreceptor degeneration in mice

  2013cited by this paper
• Explant cultures of Rpe65−/− mouse retina: a model to investigate cone opsin trafficking

  2013cited by this paper
• p38 MAPK signaling acts upstream of LIF-dependent neuroprotection during photoreceptor degeneration

  2013cited by this paper
• Transplantation of human central nervous system stem cells – neuroprotection in retinal degeneration

  2012cited by this paper
• Time course modifications in organotypic culture of human neuroretina.

  2012cited by this paper
• Cone opsin determines the time course of cone photoreceptor degeneration in Leber congenital amaurosis

  2011cited by this paper
• Further assessment of neuropathology in retinal explants and neuroprotection by human neural progenitor cells

  2011cited by this paper
• Ciliary Neurotrophic Factor Induces Genes Associated with Inflammation and Gliosis in the Retina: A Gene Profiling Study of Flow-Sorted, Müller Cells

  2011cited by this paper
• Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina

  2011cited by this paper
• Human neural progenitor cells promote photoreceptor survival in retinal explants.

  2010cited by this paper
• A Battery of Cell- and Structure-specific Markers for the Adult Porcine Retina

  2010cited by this paper
• Cone outer segment morphology and cone function in the Rpe65-/- Nrl-/- mouse retina are amenable to retinoid replacement.

  2009cited by this paper
• Cone degeneration in aging and age-related macular degeneration.

  2009cited by this paper
• Early remodeling in an inducible animal model of retinal degeneration.

  2009cited by this paper
• Maintenance of adult porcine retina and retinal pigment epithelium in perfusion culture: characterisation of an organotypic in vitro model.

  2008cited by this paper
• Long-term vision rescue by human neural progenitors in a rat model of photoreceptor degeneration.

  2008cited by this paper
• Development and characterization of an adult retinal explant organotypic tissue culture system as an in vitro intraocular stem cell transplantation model.

  2008cited by this paper
• Progenitor cell-derived factors enhance photoreceptor survival in rat retinal explants.

  2008cited by this paper
• Trafficking of Membrane-Associated Proteins to Cone Photoreceptor Outer Segments Requires the Chromophore 11-cis-Retinal

  2008cited by this paper
• Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment.

  2008cited by this paper
• Stem cells for neuroprotection in glaucoma.

  2008cited by this paper
• Novel organotypic culture model of adult mammalian neurosensory retina in co-culture with retinal pigment epithelium.

  2008cited by this paper
• Protection of Visual Functions by Human Neural Progenitors in a Rat Model of Retinal Disease

  2007cited by this paper
• Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR

  2007cited by this paper
• Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis

  2007cited by this paper
• Nuclear kinesis, neurite sprouting and abnormal axonal projections of cone photoreceptors in the aged and AMD-afflicted human retina.

  2007cited by this paper
• Structural and functional remodeling in the retina of a mouse with a photoreceptor synaptopathy: plasticity in the rod and degeneration in the cone system

  2007cited by this paper
• Dendritic and synaptic plasticity of neurons in the human age-related macular degeneration retina.

  2007cited by this paper
• bFGF promotes photoreceptor cell survival in vitro by PKA‐mediated inactivation of glycogen synthase kinase 3β and CREB‐dependent Bcl‐2 up‐regulation

  2007cited by this paper
• Activation of signaling pathways and stress-response genes in an experimental model of retinal detachment.

  2006cited by this paper
• Cellular remodeling in mammalian retina: results from studies of experimental retinal detachment.

  2005cited by this paper
• Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.

  2005cited by this paper
• Retinal remodeling during retinal degeneration.

  2005cited by this paper
• Regressive and reactive changes in the connectivity patterns of rod and cone pathways of P23H transgenic rat retina.

  2004cited by this paper
• Remodeling of second-order neurons in the retina of rd/rd mutant mice.

  2003cited by this paper
• Synaptic plasticity in mammalian photoreceptors prepared as sheets for retinal transplantation.

  2003cited by this paper
• Basic fibroblast and epidermal growth factors stimulate survival in adult porcine photoreceptor cell cultures.

  2003cited by this paper
• Retinal remodeling triggered by photoreceptor degenerations

  2003cited by this paper
• Cellular and cytoskeletal dynamics within organ cultures of porcine neuroretina.

  2002cited by this paper
• Microglia–Müller Glia Cell Interactions Control Neurotrophic Factor Production during Light-Induced Retinal Degeneration

  2002cited by this paper
• Distribution and density of medium- and short-wavelength selective cones in the domestic pig retina.

  2002cited by this paper
• Interleukin-6 increases the survival of retinal ganglion cells in vitro.

  2001cited by this paper
• The role of the retinal pigment epithelium: Topographical variation and ageing changes

  2001cited by this paper
• HSV-1 vector-delivered FGF2 to the retina is neuroprotective but does not preserve functional responses.

  2001cited by this paper
• Growth factors in combination, but not individually, rescue rd mouse photoreceptors in organ culture.

  2000cited by this paper
• Early loss of synaptic protein PSD-95 from rod terminals of rhodopsin P347L transgenic porcine retina.

  2000cited by this paper
• Photoreceptor density of the domestic pig retina.

  1999cited by this paper
• Immunocytochemical Localization of the Postsynaptic Density Protein PSD-95 in the Mammalian Retina

  1998cited by this paper
• Opsin distribution and synthesis in degenerating photoreceptors of rd mutant mice.

  1989cited by this paper
• DEVELOPMENTAL NEUROSCIENCE: Interleukin-2 and interleukin-4 increase the survival of retinal ganglion cells in culture

  year unknowncited by this paper
• © 2009 Molecular Vision Immunohistochemical study of pig retinal development

  year unknowncited by this paper

• Investigating Retinal Explant Models Cultured in Static and Perfused Systems to Test the Performance of Exosomes Secreted from Retinal Organoids.

  2024cites this paper
• Retinal debris triggers cytotoxic damage in cocultivated primary porcine RPE cells

  2024cites this paper
• Qualitative evaluations of reactive microglial heterogeneity in cultured porcine retina.

  2024cites this paper
• Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina

  2023cites this paper
• Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death

  2022cites this paper
• Stem cell transplantation as a progressing treatment for retinitis pigmentosa

  2022cites this paper
• Effects of interaction between stem cells and degenerative retinal

  2021cites this paper
• Human Retinal Progenitor Cells Derived Small Extracellular Vesicles Delay Retinal Degeneration: A Paradigm for Cell-free Therapy

  2021cites this paper
• Ex Vivo Model of Spontaneous Neuroretinal Degeneration for Evaluating Stem Cells' Paracrine Properties.

  2021cites this paper
• Cyclosporine A Protects Retinal Explants against Hypoxia

  2021cites this paper
• Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina.

  2020cites this paper
• Oxidative stress‐induced retinal damage is prevented by mild hypothermia in an ex vivo model of cultivated porcine retinas

  2020cites this paper
• Protective effects of human iPS-derived retinal pigmented epithelial cells on retinal degenerative disease

  2020cites this paper
• Intravitreal stem cell paracrine properties as a potential neuroprotective therapy for retinal photoreceptor neurodegenerative diseases

  2020cites this paper
• Human Mesenchymal Stem Cell Secretome Exhibits a Neuroprotective Effect over In Vitro Retinal Photoreceptor Degeneration

  2020cites this paper
• Morphological analyzes of microglia heterogeneity and dynamics during photoreceptor degeneration in vitro: presumptive dark microglia in porcine retina.

  2020cites this paper
• In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell‐Induced Photoreceptor Survival

  2019cites this paper
• Diminished apoptosis in hypoxic porcine retina explant cultures through hypothermia

  2019cites this paper
• Current Advancements in the Development and Characterization of Full-Thickness Adult Neuroretina Organotypic Culture Systems

  2019cites this paper
• RETRACTED ARTICLE: Role of oxidative stress in Retinitis pigmentosa: new involved pathways by an RNA-Seq analysis

  2019cites this paper
• Evaluation of Congo Red Staining in Degenerating Porcine Photoreceptors In Vitro: Protective Effects by Structural and Trophic Support

  2018cites this paper
• Quantitative Assessment of Retina Explant Viability in a Porcine Ex Vivo Neuroretina Model

  2018cites this paper
• A model to study complement involvement in experimental retinal degeneration

  2018cites this paper
• Effects of the neuroprotective drugs somatostatin and brimonidine on retinal cell models of diabetic retinopathy

  2016cites this paper