RNA polymerase unveiled.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Cell

• Publication date

  1999-09-17

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0092-8674(00)81483-XPMID 10499791
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999influential reference
• Interactions of Escherichia coli sigma(70) within the transcription elongation complex.

  1999cited by this paper
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  1999influential reference
• Transcription elongation: structural basis and mechanisms.

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• Electron crystal structure of an RNA polymerase II transcription elongation complex.

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