The molecular genetics of Wilms tumor.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Cancer Investigation

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/07357909409021393PMID 8281465
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chromosome 11 Putative Tumor Suppressor Regions , Is Limited to Loss of Heterozygosity in Wilms ' Tumors , Studied for Six Updated

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• Genetics of Wilms' tumor

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• Trisomy 11p15 and Beckwith-Wiedemann syndrome. A report of two cases

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• Results of the Sixth International Society of Pediatric Oncology Wilms' Tumor Trial and Study: a risk-adapted therapeutic approach in Wilms' tumor.

  1993cited by this paper
• Homozygous somatic Wt1 point mutations in sporadic unilateral Wilms tumor.

  1993cited by this paper
• Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome.

  1992cited by this paper
• A third Wilms' tumor locus on chromosome 16q.

  1992cited by this paper
• Loss of heterozygosity mapping in Wilms tumor indicates the involvement of three distinct regions and a limited role for nondisjunction or mitotic recombination

  1992cited by this paper
• Genetics and epidemiology of Wilms' tumor: the French Wilms' tumor study.

  1992cited by this paper
• RNA expression of the WT1 gene in Wilms' tumors in relation to histology.

  1992cited by this paper
• Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development

  1992cited by this paper
• Nonlinkage of 16q markers to familial predisposition to Wilms' tumor.

  1992cited by this paper
• Beckwith-Wiedemann syndrome, tumourigenesis and imprinting.

  1992cited by this paper
• Coordinate expression of Wilms' tumor genes correlates with Wilms' tumor phenotypes.

  1992cited by this paper
• Equivalent expression of paternally and maternally inherited WT1 alleles in normal fetal tissue and Wilms' tumours.

  1992cited by this paper
• Inherited WT1 mutation in Denys-Drash syndrome.

  1992cited by this paper
• Zinc finger point mutations within the WT1 gene in Wilms tumor patients.

  1992cited by this paper
• Expression of the 11p13 Wilms' tumor gene, WT1, correlates with histologic category of Wilms' tumor.

  1992cited by this paper
• Uniparental paternal disomy in a genetic cancer-predisposing syndrome

  1991cited by this paper
• The p53 tumour suppressor gene

  1991cited by this paper
• Alternative splicing and genomic structure of the Wilms tumor gene WT1.

  1991cited by this paper
• Chromosome 11 uniparental isodisomy predisposing to embryonal neoplasms.

  1991cited by this paper
• A tumor chromosome rearrangement further defines the 11p13 Wilms tumor locus.

  1991cited by this paper
• Regional mapping of the parathyroid hormone gene (PTH) by cytogenetic and molecular studies.

  1991cited by this paper
• Familial predisposition to Wilms tumor does not segregate with the WT1 gene.

  1991cited by this paper
• Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT.

  1991cited by this paper
• Smallest region of overlap in Wilms tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus.

  1991cited by this paper
• WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour

  1991cited by this paper
• Molecular, Cytogenetic and Linkage Analysis of Chromosome 11p Regions Involved in Wilms’ Tumour and Associated Congenital Diseases

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• Direct pulsed field gel electrophoresis of Wilms' tumors shows that dna deletions in 11 p 13 are rare

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• Structural rearrangements of the WT1 gene in Wilms' tumour cells.

  1991cited by this paper
• Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome.

  1991cited by this paper
• Parental imprinting of the mouse insulin-like growth factor II gene.

  1991cited by this paper
• Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development

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• Parental imprinting of the mouse H19 gene

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• Wilms tumor locus on 11p13 defined by multiple CpG island-associated transcripts.

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• Genomic imprinting: review and relevance to human diseases.

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• Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

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• The candidate Wilms' tumour gene is involved in genitourinary development

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• An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.

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• Loss of heterozygosity in Wilms' tumour involves two distinct regions of chromosome 11.

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  1990cited by this paper
• Genomic imprinting and the Beckwith-Wiedemann syndrome.

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• Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence.

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• Role for the Wilms tumor gene in genital development?

  1990cited by this paper
• Constitutional and somatic deletions of two different regions of maternal chromosome 11 in Wilms tumor.

  1990cited by this paper
• Clinicopathologic review of twelve children with nephropathy, Wilms tumor, and genital abnormalities (Drash syndrome).

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• Treatment of Wilms' tumor. Results of the third national Wilms' tumor study

  1989cited by this paper
• Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.

  1989cited by this paper
• Unequal parental contributions: genomic imprinting in mammals.

  1989cited by this paper
• Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells

  1989cited by this paper
• Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma.

  1989cited by this paper
• Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein.

  1989cited by this paper
• Bilateral Wilms' tumor: long-term survival and some epidemiological features.

  1989cited by this paper
• Unequal parental contributions: genomic imprinting in mammals.

  1989cited by this paper
• Maternal allele loss in Wilms' tumour.

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• Molecular definition of the 11p15.5 region involved in Beckwith-Wiedemann syndrome and probably in predisposition to adrenocortical carcinoma

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• Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.

  1989cited by this paper
• Genomic imprinting and embryonal tumours

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• Genomic imprinting and genetic disorders in man.

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• Cancer genetics. Genomic imprinting and embryonal tumours.

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• Familial predisposition to Wilms' tumour does not map to the short arm of chromosome 11

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• Age distribution of Wilms' tumor: report from the National Wilms' Tumor Study.

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• Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13

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• Homozygous deletion of a DNA marker from chromosome 11p13 in sporadic Wilms tumor.

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• Genomic imprinting and carcinogenesis.

  1988cited by this paper
• Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumours

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• Experimental reconstruction of mouse eggs and embryos: an analysis of mammalian development.

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• Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors.

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• [Association of an anatomo-pathological syndrome of male pseudohermaphroditism, Wilms' tumor, parenchymatous nephropathy and XX/XY mosaicism].

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