Opportunities and challenges of personalized therapy of patients with HR ALL

S. Izraeli

Published 2019 in HemaSphere

ABSTRACT

The opportunities: Novel genomic diagnostics and availability of multiple new drugs create opportunities for personalized adjustment of therapy for HR ALL patients. The major challenges: Lack of reliable efficacy data and of specific clinical trials. Recommendations: Be conservative minimize deviations from clinical protocols; Whenever possible enroll the patient in a specific clinical trial for the novel therapy; If not available–maximize local and central prospective collection of clinical and biological data on each patient.

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