Formula to Correct Left Ventricular Ejection Fraction in Patients with Mitral Valve Regurgitation

Left ventricular ejection fraction is a key measurement for the assessment of systolic function. In case of mitral valve insufficiency,part of the ejected volume regurgitates to the left atrium, the anterograde volume is less than expected, and theejection fraction maintains a value that does not adequately represent the inotropic state. This does not allow certain patientswith heart failure to be correctly classified and treated, especially regarding the indication of devices (resynchronizationtherapy and defibrillator implant). Based on the calculation of the regurgitant fraction, we propose a simple formula to makea “correction” of the ejection fraction in this type of cases. The corrected ejection fraction was tested in a group of consecutiveoutpatients. The study confirmed that 54% of patients have their prognosis and/or treatment modified when applyingthe proposed formula.

• Publication year

  2019

• Venue

  Revista Argentina de Cardiología

• Publication date

  2019-04-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.7775/RAC.87.3.15163
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance.

  2017cited by this paper
• Secondary mitral regurgitation in heart failure: pathophysiology, prognosis, and therapeutic considerations.

  2015cited by this paper
• Roadmap for biomarkers of cancer therapy cardiotoxicity

  2015cited by this paper
• Left ventricular performance is closely related to the physical properties of the arterial system: Landmark clinical investigations in the 1970s and 1980s.

  2014cited by this paper
• Changes in left ventricular function after mitral valve repair for severe organic mitral regurgitation.

  2012cited by this paper
• Epidemiology and risk profile of heart failure

  2011cited by this paper
• Treatment of heart failure with normal ejection fraction: an inconvenient truth!

  2010cited by this paper
• Left ventricular response to mitral regurgitation: implications for management.

  2008cited by this paper
• Aortic Regurgitation

  2006cited by this paper

• No citing papers are available for this paper.