Current pharmacotherapy options for type 2 diabetes

S. Habtemariam

Published 2019 in Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

ABSTRACT

Abstract The goal of type 2 diabetes (T2D) therapy is to achieve outcomes that are associated with the diagnosis of the disease itself and centred at reversing the increased levels of blood glucose and glycated haemoglobin. The common approaches in T2D management are lifestyle changes such as dietary control and exercise regimens as well as pharmacotherapy interventions. This chapter outlines the chemical and pharmacological profiles of the current T2D drugs of choices. The various classes of compounds starting from the old drugs of biguanides represented by metformin to new additions in recent years are exhibited. Among the other classes of drugs detailed are the glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) analogues and receptor agonists; dipeptidyl peptidase-4 (DPP-4), sodium–glucose cotransporter-2 (SGL2) and α-glucosidase inhibitors; sulfonylureas and meglitinides; thiazolidinedione; insulin preparations, etc.

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REFERENCES

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