Dephosphorylation of fetal-tau and paired helical filaments-tau by protein phosphatases 1 and 2A and calcineurin.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Journal of Biochemistry (Tokyo)

• Publication date

  1995-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/OXFORDJOURNALS.JBCHEM.A125011PMID 8720139
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dephosphorylation of abnormal sites of tau factor by protein phosphatases and its implication for Alzheimer's disease.

  1995cited by this paper
• Dephosphorylation of Alzheimer Paired Helical Filaments by Protein Phosphatase-2A and −2B (*)

  1995cited by this paper
• Alzheimer's Disease Abnormally Phosphorylated τ Is Dephosphorylated by Protein Phosphatase‐2B (Calcineurin)

  1994cited by this paper
• Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

  1994cited by this paper
• Dephosphorylation of microtubule‐associated protein tau by protein phosphatase‐1 and ‐2C and its implication in Alzheimer disease

  1994cited by this paper
• Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

  1993cited by this paper
• Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase‐2A

  1993cited by this paper
• The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.

  1993cited by this paper
• In vivo phosphorylation sites in fetal and adult rat tau.

  1993cited by this paper
• Characterization of Two Distinct Monoclonal Antibodies to Paired Helical Filaments: Further Evidence for Fetal‐Type Phosphorylation of the τ in Paired Helical Filaments

  1993cited by this paper
• Protein Kinase FA/GSK‐3 Phosphorylates on Ser235‐Pro and Ser404‐Pro that Are Abnormally Phosphorylated in Alzheimer's Disease Brain

  1993cited by this paper
• Fetal-type phosphorylation of the tau in paired helical filaments.

  1992cited by this paper
• Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

  1992cited by this paper
• Purification and characterization of a novel proline-directed protein kinase from bovine brain.

  1992cited by this paper
• Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments.

  1992cited by this paper
• Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain.

  1992cited by this paper
• Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer‐like state.

  1992cited by this paper
• p42 map kinase phosphorylation sites in microtubule‐associated protein tau are dephosphorylated by protein phosphatase 2A1 Implications for Alzheimer's disease

  1992cited by this paper
• Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

  1992cited by this paper
• A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

  1991cited by this paper
• Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease.

  1989cited by this paper
• Expression of rat protein phosphatase 2C (IA) in Escherichia coli.

  1989cited by this paper
• Dephosphorylation of Microtubule Proteins by Brain Protein Phosphatases 1 and 2A, and Its Effect on Microtubule Assembly

  1988cited by this paper
• Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease.

  1986cited by this paper
• Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

  1986cited by this paper
• Dephosphorylation of Microtubule‐Associated Protein 2, τ Factor, and Tubulin by Calcineurin

  1985cited by this paper
• Ca2+-induced hydrophobic site on calmodulin: application for purification of calmodulin by phenyl-Sepharose affinity chromatography.

  1982cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Calcineurin in cancer signaling networks

  2025cites this paper
• Distinct tau folds initiate templated seeding and alter the post-translational modification profile

  2023cites this paper
• Prion-Like Propagation Mechanisms in Tauopathies and Traumatic Brain Injury: Challenges and Prospects

  2020cites this paper
• Pore-former enabled seeding of tau in rats: Alleviation by memantine and lithium chloride.

  2019cites this paper
• Structure of NFT: Biochemical Approach.

  2019cites this paper
• Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders.

  2017cites this paper
• Fonctions atypiques de la protéine Tau : rôles dans la protection des acides nucléiques et le métabolisme des ARN

  2016cites this paper
• Molecular Mechanisms in the Pathogenesis of Alzheimer’s disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation

  2016cites this paper
• Aberrant Expression of RCAN1 in Alzheimer’s Pathogenesis: A New Molecular Mechanism and a Novel Drug Target

  2014cites this paper
• Nmnat2 Attenuates Tau Phosphorylation Through Activation of PP2A

  2013cites this paper
• Isomerase Pin1 Stimulates Dephosphorylation of Tau Protein at Cyclin-dependent Kinase (Cdk5)-dependent Alzheimer Phosphorylation Sites*

  2013cites this paper
• PTPA activates protein phosphatase-2A through reducing its phosphorylation at tyrosine-307 with upregulation of protein tyrosine phosphatase 1B.

  2013cites this paper
• Human fetal tau protein isoform: possibilities for Alzheimer's disease treatment.

  2012influential citation
• Glycogen synthase kinase-3β regulates Tyr307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src.

  2011cites this paper
• Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau

  2011cites this paper
• Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome.

  2010cites this paper
• Effect of Pin1 or Microtubule Binding on Dephosphorylation of FTDP-17 Mutant Tau*

  2009cites this paper
• Gene Expression Profiles in the Olfactory Bulb from a Rat Model of Alzheimer's Disease

  2009cites this paper
• FTDP-17 missense mutations site-specifically inhibit as well as promote dephosphorylation of microtubule-associated protein tau by protein phosphatases of HEK-293 cell extract.

  2009cites this paper
• Tau in neurodegenerative diseases: Tau phosphorylation and assembly

  2009cites this paper
• The localization of c-Abl in Alzheimer's disease

  2008cites this paper
• Specificity and Regulation of Casein Kinase-Mediated Phosphorylation of &agr;-Synuclein

  2008cites this paper
• Regulation of vascular endothelial cell barrier function and cytoskeleton structure by protein phosphatases of the PPP family.

  2007cites this paper
• Tauopathies

  2007cites this paper
• Tau and tauopathies.

  2007cites this paper
• Implication de la protéine tau dans la dégénérescence neuronale in vitro

  2006cites this paper
• Hyperphosphorylation of tau and protein phosphatases in Alzheimer disease.

  2006cites this paper
• PP2B isolated from human brain preferentially dephosphorylates Ser-262 and Ser-396 of the Alzheimer disease abnormally hyperphosphorylated tau

  2006cites this paper
• Hyperphosphorylation at serine 199/202 of tau factor in the gerbil hippocampus after transient forebrain ischemia.

  2006cites this paper
• Regulation of the kinase MARK from Rattus norvegicus (Berkenhout, 1769): activation by MARKK and inhibition by PAK5

  2006cites this paper
• Regulation of the kinase MARK from

  2006cites this paper
• [Regulation of phosphorylation of tau by insulin and Ca2+ signals].

  2005cites this paper
• Effect of melatonin on calyculin A-induced tau hyperphosphorylation.

  2005cites this paper
• The role of GSK‐3β in the formation of neurofibrillary tangles

  2004cites this paper
• Role of tau protein in both physiological and pathological conditions.

  2004cites this paper
• Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent‐insoluble membrane fraction in Niemann–Pick C1‐deficient cells

  2003cites this paper
• Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats.

  2003cites this paper
• Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites.

  2002cites this paper
• [Neurofibrillary tangles and neurodegenerative disease].

  2002cites this paper
• Enhancement by cyclosporin A of taxol-induced apoptosis of human urinary bladder cancer cells

  2002cites this paper
• Tau protein isoforms, phosphorylation and role in neurodegenerative disorders.

  2000cites this paper
• Phosphorylation of Microtubule-associated Protein Tau Is Regulated by Protein Phosphatase 2A in Mammalian Brain

  2000cites this paper
• Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.

  2000cites this paper
• The expression of casein kinase 2α′ and phosphatase 2A activity

  1999cites this paper
• Sequence of neurodegeneration and accumulation of phosphorylated tau in cultured neurons after okadaic acid treatment.

  1999cites this paper
• The expression of casein kinase 2alpha' and phosphatase 2A activity.

  1999cites this paper
• Subcellular distribution of protein phosphatases and abnormally phosphorylated τ in the temporal cortex from Alzheimer's disease and control brains

  1998cites this paper
• Familial multiple system degeneration associated with iron deposition: determination of subcellular localization of elementary iron by energy-dispersive X-ray analysis.

  1998cites this paper
• Microtubule-stimulated phosphorylation of tau at Ser202 and Thr205 by cdk5 decreases its microtubule nucleation activity.

  1998cites this paper
• The interrelationship between selective tau phosphorylation and microtubule association.

  1998cites this paper
• The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.

  1997cites this paper
• Normal and pathological Tau proteins as factors for microtubule assembly.

  1997cites this paper
• Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

  1996cites this paper