ERK and p38 pathways regulate amino acid signalling.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Biochimica et Biophysica Acta

• Publication date

  2008-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.bbamcr.2008.08.011PMID 18809440
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MEK Signaling Is Required for Phosphorylation of eIF2α following Amino Acid Limitation of HepG2 Human Hepatoma Cells*

  2008cited by this paper
• Control of the Autophagy Maturation Step by the MAPK ERK and p38: Lessons from Environmental Carcinogens

  2007cited by this paper
• A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

  2007cited by this paper
• MAP kinase pathways: the first twenty years.

  2007cited by this paper
• Autophagy: from phenomenology to molecular understanding in less than a decade

  2007influential reference
• Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

  2007cited by this paper
• Regulation of MAPKs by growth factors and receptor tyrosine kinases.

  2007cited by this paper
• A clickable inhibitor reveals context-dependent autoactivation of p90 RSK.

  2007cited by this paper
• The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

  2007cited by this paper
• RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation*

  2007influential reference
• RSK and MSK in MAP kinase signalling

  2006cited by this paper
• Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity.

  2006cited by this paper
• Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase

  2006cited by this paper
• Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

  2006cited by this paper
• Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

  2006cited by this paper
• TSC1 Stabilizes TSC2 by Inhibiting the Interaction between TSC2 and the HERC1 Ubiquitin Ligase*

  2006cited by this paper
• Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low‐percentage acrylamide gel and a gradient SDS‐PAGE gel

  2006cited by this paper
• TOR signaling in growth and metabolism.

  2006influential reference
• Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

  2005influential reference
• Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins

  2005cited by this paper
• hVps34 Is a Nutrient-regulated Lipid Kinase Required for Activation of p70 S6 Kinase*

  2005cited by this paper
• Structure of S6 Kinase 1 Determines whether Raptor-mTOR or Rictor-mTOR Phosphorylates Its Hydrophobic Motif Site*♦

  2005cited by this paper
• Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage

  2005cited by this paper
• Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth.

  2005cited by this paper
• The giant protein HERC1 is recruited to aluminum fluoride‐induced actin‐rich surface protrusions in HeLa cells

  2004cited by this paper
• S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

  2004cited by this paper
• Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells.

  2004cited by this paper
• Activation of p90Rsk1 Is Sufficient for Differentiation of PC12 Cells

  2004cited by this paper
• Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase.

  2003cited by this paper
• The Mammalian Target of Rapamycin (mTOR) Partner, Raptor, Binds the mTOR Substrates p70 S6 Kinase and 4E-BP1 through Their TOR Signaling (TOS) Motif*

  2003cited by this paper
• mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

  2002cited by this paper
• Ribosomal S6 Kinase 2 Inhibition by a Potent C-terminal Repressor Domain Is Relieved by Mitogen-activated Protein-Extracellular Signal-regulated Kinase Kinase-regulated Phosphorylation*

  2001cited by this paper
• Stress-induced Inhibition of ERK1 and ERK2 by Direct Interaction with p38 MAP Kinase*

  2001cited by this paper
• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  2000cited by this paper
• Farnesyltransferase Inhibitor Induces Rapid Growth Arrest and Blocks p70s6k Activation by Multiple Stimuli*

  2000cited by this paper
• Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation.

  1999cited by this paper
• Amino Acid-dependent Control of p70s6k

  1999cited by this paper
• Requirement of activation of JNK and p38 for environmental stress-induced erythroid differentiation and apoptosis and of inhibition of ERK for apoptosis.

  1999cited by this paper
• Regulation of the p70 S6 Kinase by Phosphorylation in Vivo

  1998cited by this paper
• Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism*

  1998influential reference
• The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

  1996cited by this paper
• p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.

  1996cited by this paper
• Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002.

  1996cited by this paper
• Phosphorylation of Ribosomal Protein S6 Is Inhibitory for Autophagy in Isolated Rat Hepatocytes (*)

  1995cited by this paper
• Nuclear localization of p85s6k: functional requirement for entry into S phase.

  1994cited by this paper
• Differential subcellular localisation of two isoforms of p70 S6 protein kinase.

  1994cited by this paper
• Induction of autophagy by amino-acid deprivation in perfused rat liver

  1977cited by this paper
• ReviewNutrient overload , insulin resistance , and ribosomal protein S 6 kinase 1 , S 6 K 1

  year unknowncited by this paper

• Anti-inflammatory role of extracellular l-arginine through calcium sensing receptor in human renal proximal tubular epithelial (HK-2) cells.

  2023cites this paper
• Carnosine Synthase 1 Contributes to Interferon Gamma-Induced Arginine Depletion via Mitogen-activated Protein Kinase 11 Signaling in Bovine Mammary Epithelial Cells

  2022cites this paper
• HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

  2022cites this paper
• Harnessing the Co-vulnerabilities of Amino Acid-Restricted Cancers.

  2021cites this paper
• Environmental Exposures around Conception: Developmental Pathways Leading to Lifetime Disease Risk

  2021cites this paper
• Human Skin Keratinocytes on Sustained TGF-β Stimulation Reveal Partial EMT Features and Weaken Growth Arrest Responses

  2020cites this paper
• mTORC2 Is Involved in the Induction of RSK Phosphorylation by Serum or Nutrient Starvation

  2020cites this paper
• p38-Mitogen Activated Kinases Mediate a Developmental Regulatory Response to Amino Acid Depletion and Associated Oxidative Stress in Mouse Blastocyst Embryos

  2019cites this paper
• Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart

  2019cites this paper
• Electromyostimulation with blood flow restriction enhances activation of mTOR and MAPK signaling pathways in rat gastrocnemius muscles.

  2019cites this paper
• Asiatic Acid Induces Apoptosis and Autophagy and Reduces MiR-17 and MiR-21 Expression in Pancreatic Cancer Cell Lines

  2019cites this paper
• Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation

  2018influential citation
• Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

  2017cites this paper
• Mesenchymal stem cells improves survival in LPS‐induced acute lung injury acting through inhibition of NETs formation

  2017cites this paper
• Nutrient sensing signaling integrates nutrient metabolism and intestinal immunity in grass carp, Ctenopharyngodon idellus after prolonged starvation

  2017cites this paper
• Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways

  2017cites this paper
• The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor‐Mediated Proliferation of SNU‐407 Colon Cancer Cells

  2016cites this paper
• The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons*

  2016cites this paper
• Big vs powerful : molecular signalling responses to hypertrophic and power resistance exercise modalities

  2015cites this paper
• TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling

  2015cites this paper
• Amino Acids Attenuate Insulin Action on Gluconeogenesis and Promote Fatty Acid Biosynthesis via mTORC1 Signaling Pathway in trout Hepatocytes

  2015cites this paper
• Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells

  2015cites this paper
• A Mycobacterial Phosphoribosyltransferase Promotes Bacillary Survival by Inhibiting Oxidative Stress and Autophagy Pathways in Macrophages and Zebrafish*

  2015cites this paper
• Rapid analyses of proteomes and interactomes using an integrated solid-phase extraction-liquid chromatography-MS/MS system.

  2015cites this paper
• The E3 Ubiquitin Protein Ligase HERC2 Modulates the Activity of Tumor Protein p53 by Regulating Its Oligomerization*

  2014cites this paper
• Caracterización funcional de la interacción de la proteïna p53 con la ubiquitina ligasa HERC2

  2014cites this paper
• Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells.

  2014cites this paper
• Role of mTOR Downstream Effector Signaling Molecules in Francisella Tularensis Internalization by Murine Macrophages

  2013cites this paper
• Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids*

  2013cites this paper
• Molecular Characterization and Expression Analysis of S6K1 in Cashmere Goats (Capra hircus)

  2013cites this paper
• Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide

  2013cites this paper
• Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates mTOR signal pathways and protein translation in the rat frontal cortex.

  2013influential citation
• Effects of time of day on resistance exercise-induced anabolic signaling in skeletal muscle

  2013cites this paper
• CD98 Increases Renal Epithelial Cell Proliferation by Activating MAPKs

  2012cites this paper
• Arf6 promotes cell proliferation via the PLD‐mTORC1 and p38MAPK pathways

  2012cites this paper
• Early postmortem gene expression and its relationship to composition and quality traits in pig Longissimus dorsi muscle.

  2012cites this paper
• Survival by self-destruction: a role for autophagy in the placenta?

  2012cites this paper
• p38 MAPK regulates calcium signal-mediated lipid accumulation through changing VDR expression in primary preadipocytes of mice

  2012cites this paper
• Atg9 cycling: The molecular mechanisms of anterograde and retrograde Atg9 trafficking

  2011cites this paper
• Age-Associated Alterations in the F344XBN Rat Heart and the Efficacy of Chronic Acetaminophen Ingestion as a Therapeutic Approach

  2011cites this paper
• Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling*

  2010cites this paper
• New insights into the function of Atg9

  2010cites this paper
• Chronic acetaminophen attenuates age-associated increases in cardiac ROS and apoptosis in the Fischer Brown Norway rat

  2010influential citation
• Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

  2010cites this paper
• Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis

  2010cites this paper
• A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1

  2009cites this paper