Saliva Aspartate Aminotransferase in Acute Myocardial Infarction

Mohammad-Reza Mirzaii-Dizgah,Mohammad-Hossein Mirzaii-Dizgah,I. Mirzaii-Dizgah

Published 2019 in Annals of Military and Health Sciences Research

ABSTRACT

Background: Precise and quick diagnosis of AMI is of main medical and pecuniary concerns. Objectives: The aim of this study was to detect saliva total aspartate aminotransferase (AST) activity -as an available guideline- in patients suffering from acute myocardial infarction (AMI). Methods: Acase-controlstudywasperformedin31subjectsasthecontrolgroupand31onesastheAMIgroup. Salivaandserumtotal AST activities were measured in the first and second mornings following the AMI by IFCC method. Mann-Whitney U and Spearman rho tests were performed as statistical analyses. Results: AST activities in both serum and saliva in the resting and stimulated conditions were significantly greater in the AMI than thehealthycontrols(P< 0.05). Furthermore,serumASTshowedasignificantpartialcorrelationwithrestingsalivaASTinbothfirst andsecondmorningsfollowingtheAMI(rho=0.368,P=0.017andrho=0.352,P=0.024,respectively)andalsowithstimulatedsaliva AST (rho = 0.331, P = 0.034, rho = 0.443, P = 0.003, respectively). Conclusions: It presumes that saliva AST may be used as a biomarker in the patients suffering from acute myocardial infarction.

PUBLICATION RECORD

  • Publication year

    2019

  • Venue

    Annals of Military and Health Sciences Research

  • Publication date

    2019-07-08

  • Fields of study

    Medicine

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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