Skin repair technology

Abstract Most wounds heal in a few days to a few weeks. However, even with the vast advances in today's healthcare technology, some wounds do not heal as expected and become chronic. Both acute and chronic wounds can have a significant impact on patients' quality of life and high demand on healthcare services. Reducing this burden and improving the outcome for patients is the aim of wound treatment. There are many different treatment options currently available, which can be broadly classified into dressings, drugs, devices, surgery, and biologic therapies, and patients may require a combination of these to achieve healing. This chapter describes the causes of wounds, the factors that can affect healing, and the principles of wound management.

• Publication year

  2019

• Venue

  Biomaterials for Skin Repair and Regeneration

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1016/B978-0-08-102546-8.00002-9
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus.

  2018cited by this paper
• Use of Oxygen Therapies in Wound Healing.

  2017cited by this paper
• Epidermal grafting versus split-thickness skin grafting for wound healing (EPIGRAAFT): study protocol for a randomised controlled trial

  2016cited by this paper
• Negative-Pressure Wound Therapy: A Comprehensive Review of the Evidence

  2016cited by this paper
• Antimicrobial stewardship in wound care: a Position Paper from the British Society for Antimicrobial Chemotherapy and European Wound Management Association.

  2016cited by this paper
• A prospective, multicentre study on the use of epidermal grafts to optimise outpatient wound management

  2016cited by this paper
• Estimating the costs associated with the management of patients with chronic wounds using linked routine data

  2016cited by this paper
• Debridement for venous leg ulcers.

  2015cited by this paper
• Challenges in the Treatment of Chronic Wounds

  2015cited by this paper
• Lower‐extremity ulcers: diagnosis and management

  2015cited by this paper
• A review of the international Burn Injury Database (iBID) for England and Wales: descriptive analysis of burn injuries 2003–2011

  2015cited by this paper
• Health economic burden that wounds impose on the National Health Service in the UK

  2015cited by this paper
• Negative pressure wound therapy for treating leg ulcers.

  2015cited by this paper
• Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity

  2014cited by this paper
• Antibacterial Efficacy Testing of a Bioelectric Wound Dressing Against Clinical Wound Pathogens

  2014cited by this paper
• Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention.

  2014cited by this paper
• Negative pressure wound therapy for treating pressure ulcers.

  2014cited by this paper
• Clinical application of growth factors and cytokines in wound healing

  2014cited by this paper
• Autologous platelet-rich plasma for treating chronic wounds.

  2013cited by this paper
• EWMA document: Antimicrobials and non-healing wounds. Evidence, controversies and suggestions.

  2013cited by this paper
• Attenuation of the Transforming Growth Factor β-Signaling Pathway in Chronic Venous Ulcers

  2010cited by this paper
• Factors Affecting Wound Healing

  2010cited by this paper
• Antibiotics and antiseptics for venous leg ulcers.

  2010cited by this paper
• Assessment of a patient with a wound

  2009cited by this paper
• The resource impact of wounds on health-care providers in Europe.

  2009cited by this paper
• Human skin wounds: A major and snowballing threat to public health and the economy

  2009cited by this paper
• A review of gene and stem cell therapy in cutaneous wound healing.

  2009cited by this paper
• Deregulation of keratinocyte differentiation and activation: a hallmark of venous ulcers

  2008cited by this paper
• Debridement for surgical wounds.

  2008cited by this paper
• Progress and opportunities for tissue-engineered skin

  2007cited by this paper
• Chronic Wound Pathogenesis and Current Treatment Strategies: A Unifying Hypothesis

  2006cited by this paper
• Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

  2006cited by this paper
• Wound assessment

  2006cited by this paper
• Excessive neutrophils characterize chronic pressure ulcers

  2003cited by this paper
• Wound bed preparation: a systematic approach to wound management

  2003cited by this paper
• Debridement of diabetic foot ulcers.

  2002cited by this paper
• Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors

  1999cited by this paper
• A small, physiological electric field orients cell division.

  1999cited by this paper
• Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds.

  1998cited by this paper
• Vacuum‐Assisted Closure: A New Method for Wound Control and Treatment: Clinical Experience

  1997cited by this paper
• Vacuum‐Assisted Closure: A New Method for Wound Control and Treatment: Animal Studies and Basic Foundation

  1997cited by this paper
• Human keratinocytes migrate to the negative pole in direct current electric fields comparable to those measured in mammalian wounds.

  1996cited by this paper
• Inhibition of cell proliferation by chronic wound fluid

  1993cited by this paper
• Human skin battery potentials and their possible role in wound healing

  1983cited by this paper
• Formation of the Scab and the Rate of Epithelization of Superficial Wounds in the Skin of the Young Domestic Pig

  1962cited by this paper

• Towards the Development of a Novel Ex Ovo Model of Infection to Pre-Screen Biomaterials Intended for Treating Chronic Wounds

  2020influential citation
• Molecular Docking Analysis of Chlorogenic Acid Against Matrix Metalloproteinases (MMPs)

  2020cites this paper