Isonicotinoylhydrazide modified 3-acetylcoumarin scaffold as an efficient chemical reversible sensor to detect Al3+ selectively and its application in live cells imaging

Wenling Wang,Lei Jin,Yangfang Kuang,Zhong-Qing Yuan,Qingming Wang

Published 2019 in Synthetic Communications

ABSTRACT

Abstract A turn-on photochromic sensor based on coumarin was designed and synthesized for selective and sensitive detection of Aluminium(III) (Al3+) in ethanol (C2H5OH)/water (H2O; 1:1, v/v) with the detection limit of 0.126 μM. The mechanism was proposed to form a kind of 1:1-type complex between probe C1 and Al3+ in which the binding constant was 3.11 × 107 M−1. In addition, the sensor was effectively used for the detection of Al3+ in living HEK293T cells. Graphical Abstract A new “turn-on” chemodosimeter exhibited instant / reversible and excellent specificity towards Al3+ in aqueous media and living cells.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-41 of 41 references · Page 1 of 1