Kinase-interacting substrate screening is a novel method to identify kinase substrates

A novel method called kinase-interacting substrate screening based on affinity beads coated with the kinase of interest identifies phosphorylation sites for Rho-kinase and others, which reveals that Rho-kinase substrate Scrib plays a crucial role in the regulation of subcellular contractility by assembling with Rho-kinase and Shroom2.

• Publication year

  2015

• Venue

  Journal of Cell Biology

• Publication date

  2015-06-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201412008PMID 26101221PMCID 4477863
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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