Selective Proteolytic Processing of Rat Hepatic Sterol Regulatory Element Binding Protein-1 (SREBP-1) and SREBP–2 During Postnatal Development*

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Biological Chemistry

• Publication date

  2003-02-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1074/jbc.M212846200PMID 12488438
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1997cited by this paper
• The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.

  1997cited by this paper
• Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis.

  1995cited by this paper
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  1993cited by this paper
• Hormonal control of fatty acid oxidation during the neonatal period.

  1992cited by this paper
• Dietary polyunsaturated fats uniquely suppress rat liver fatty acid synthase and S14 mRNA content.

  1990cited by this paper
• Binding of zinc and calcium to inositol phosphates (phytate) in vitro

  1990cited by this paper
• Insulin rapidly induces rat liver S14 gene transcription.

  1990cited by this paper
• Transcriptional activation of the rat liver S14 gene during postnatal development.

  1988cited by this paper
• Rat hepatic mRNA-S14 and lipogenic enzymes during weaning: role of S14 in lipogenesis.

  1987cited by this paper
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  1986cited by this paper
• High basal expression and 3,5,3'-triiodothyronine regulation of messenger ribonucleic acid S14 in lipogenic tissues.

  1985cited by this paper
• Postnatal development: coordination of feeding, digestion, and metabolism.

  1981cited by this paper

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  2013cites this paper
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  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2010cites this paper
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  2009cites this paper
• Reverse modulation of the HDL anionic peptide factor and phospholipid transfer protein activity in coronary artery disease and type 2 diabetes mellitus.

  2009cites this paper
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  2009cites this paper
• Docosahexaenoic Acid (DHA) and Hepatic Gene Transcription, 1,3

  2009influential citation
• Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin.

  2009cites this paper
• Docosahexaenoic acid (DHA) and hepatic gene transcription.

  2008cites this paper
• N-3 polyunsaturated fatty acid regulation of hepatic gene transcription

  2008cites this paper
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  2007cites this paper
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  2007cites this paper
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  2006cites this paper
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  2006cites this paper
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  2005cites this paper
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  2005influential citation
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  2005cites this paper
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  2003cites this paper